Results 161 to 170 of about 1,460,729 (292)
Advanced Healthcare Materials, EarlyView.Decellularized liver extracellular matrix scaffolds provide a platform to study dormant liver‐metastatic colorectal cancer. They induce reversible dormancy, in combination with nutrient depletion and low dose chemotherapy, through cell cycle arrest and chemotherapy resistance.
Sabrina N. VandenHeuvel +13 more
wiley +1 more source
At the Pointy End of Mechanobiology: AFM for Transient Biomechanical Analysis
Advanced Healthcare Materials, EarlyView.Stem cell mechanosensitivity governs lineage commitment through mechanotransduction, but capturing these transient changes in living cells remains challenging. Advanced atomic force microscopy enables high‐resolution analysis of mechanical properties, real‐time protein distribution, and gene expression, offering fresh insights into cell‐environment ...
Kaiwen Zhang +5 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.Six stereoisomeric ruthenium‐peptide conjugates were synthesized and characterized, which showed high potential in photoactivated chemotherapy (PACT) and proximity protein labeling. Abstract Amino acid chirality is known to influence the biological properties of peptide‐containing prodrugs.
Liyan Zhang +7 more
wiley +1 more source
Transforming Cancer Diagnosis and Therapy Through Fluorescent Hydrogels: A Review
Advanced Healthcare Materials, EarlyView.This article reviews fluorescent hydrogel systems for cancer detection, monitoring, and therapy. Mimicking the tumor microenvironment, these hydrogels enable real‐time imaging and targeted drug delivery. The review discusses design strategies, labeling techniques, and applications, highlighting challenges and future opportunities in cancer diagnostics ...
Elahe Masaeli +2 more
wiley +1 more source
Deep Docking: A Deep Learning Platform for Augmentation of Structure Based Drug Discovery
ACS Central Science, 2020 Francesco Gentile +7 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.Recent advances in diagnostics have accelerated the development of miniaturized wearable technologies for the continuous monitoring of diseases. This paradigm is shifting healthcare away from invasive, centralized blood tests toward decentralized monitoring, using alternative body biofluids.
Lanka Tata Rao +2 more
wiley +1 more source
Impact of intrafraction fiducial tracking on planning target margins during prostate stereotactic body radiotherapy using Brainlab ExacTrac Dynamic with robotic couch correction. [PDF]
J Appl Clin Med PhysWorth M, Brancato DC, Lo J, Kole TP.
europepmc +1 more source
Harnessing Next‐Generation 3D Cancer Models to Elucidate Tumor‐Microbiome Crosstalk
Advanced Healthcare Materials, EarlyView.Centralizes the microbiome within 3D tumor‐microbiome model platforms, including spheroids, organoids, 3D‐bioprinted constructs, and microfluidic chips, each enabling structured host‐tumor‐microbe studies. These systems support bacterial colonization, facilitating investigation of microbial impacts on tumor growth, immunity, and therapy. The microbiome
Marina Green Buzhor +12 more
wiley +1 more source
Trajectories and predictors of frailty in older patients undergoing radical prostatectomy: A longitudinal study. [PDF]
Asia Pac J Oncol NursLiu Y +8 more
europepmc +1 more source