Results 11 to 20 of about 1,273,410 (345)

Prostatitis [PDF]

Canadian Urological Association Journal, 2001
Prostatitis is a common condition that accounts for a significant number of visits to both the emergency department and the urologist. The precise pathogenic mechanism of prostatitis is not known. The most prevalent theory is that reflux of urine from the urethra into the intraprostatic ducts promotes ascending infection and leads to chemical or ...
W E, Lummus, I, Thompson
  +9 more sources

Prostatitis [PDF]

Hospital Medicine, 1999
Prostatitis, especially chronic prostatitis, is sometimes regarded as an obscure, ill-defined condition, perhaps because the anatomical location of the gland and ill-defined symptoms make diagnosis difficult. Treatment may appear time consuming and tiresome for doctor and patient, but by following established principles, diagnosis is often simple and ...
Ch, Theodorou, Th, Becopoulos
openaire   +4 more sources

Sipuleucel-T immunotherapy for castration-resistant prostate cancer.

New England Journal of Medicine, 2010
BACKGROUND Sipuleucel-T, an autologous active cellular immunotherapy, has shown evidence of efficacy in reducing the risk of death among men with metastatic castration-resistant prostate cancer.
P. Kantoff, C. Higano, N. Shore, E. Berger, E. Small, D. Penson, C. Redfern, A. Ferrari, R. Dreicer, R. Sims, Yi Xu, M. Frohlich, P. Schellhammer   +12 more
semanticscholar   +1 more source

SEMA3C drives cancer growth by transactivating multiple receptor tyrosine kinases via Plexin B1

EMBO Molecular Medicine, 2018
Growth factor receptor tyrosine kinase (RTK) pathway activation is a key mechanism for mediating cancer growth, survival, and treatment resistance. Cognate ligands play crucial roles in autocrine or paracrine stimulation of these RTK pathways.
James W Peacock, Ario Takeuchi, Norihiro Hayashi, Liangliang Liu, Kevin J Tam, Nader Al Nakouzi, Nastaran Khazamipour, Tabitha Tombe, Takashi Dejima, Kevin CK Lee, Masaki Shiota, Daksh Thaper, Wilson CW Lee, Daniel HF Hui, Hidetoshi Kuruma, Larissa Ivanova, Parvin Yenki, Ivy ZF Jiao, Shahram Khosravi, Alice L‐F Mui, Ladan Fazli, Amina Zoubeidi, Mads Daugaard, Martin E Gleave, Christopher J Ong   +24 more
doaj   +1 more source

Small extracellular vesicle-mediated ITGB6 siRNA delivery downregulates the αVβ6 integrin and inhibits adhesion and migration of recipient prostate cancer cells

Cancer Biology & Therapy, 2022
The αVβ6 integrin, an epithelial-specific cell surface receptor absent in normal prostate and expressed during prostate cancer (PrCa) progression, is a therapeutic target in many cancers.
Shiv Ram Krishn, Vaughn Garcia, Nicole M. Naranjo, Fabio Quaglia, Christopher D. Shields, Maisha A. Harris, Andrew V. Kossenkov, Qin Liu, Eva Corey, Dario C. Altieri, Lucia R. Languino   +10 more
doaj   +1 more source

10-Year Outcomes after Monitoring, Surgery, or Radiotherapy for Localized Prostate Cancer.

New England Journal of Medicine, 2017
BACKGROUND The comparative effectiveness of treatments for prostate cancer that is detected by prostate-specific antigen (PSA) testing remains uncertain.
F. C. Hamdy, J. Donovan, J. Lane, M. Mason, C. Metcalfe, P. Holding, M. Davis, T. Peters, E. Turner, Richard M. Martin, J. Oxley, M. Robinson, J. Staffurth, E. Walsh, P. Bollina, J. Catto, A. Doble, A. Doherty, D. Gillatt, R. Kockelbergh, H. Kynaston, A. Paul, P. Powell, S. Prescott, D. Rosario, E. Rowe, D. E. Neal, D. E. Neal   +27 more
semanticscholar   +1 more source

NCCN Guidelines Insights: Prostate Cancer, Version 1.2021.

The Journal of the National Comprehensive Cancer Network, 2021
The NCCN Guidelines for Prostate Cancer address staging and risk assessment after a prostate cancer diagnosis and include management options for localized, regional, and metastatic disease.
E. Schaeffer, S. Srinivas, E. Antonarakis, A. Armstrong, J. Bekelman, Heather H. Cheng, A. D'Amico, B. Davis, N. Desai, T. Dorff, J. Eastham, T. Farrington, Xin Gao, E. Horwitz, J. Ippolito, M. Kuettel, J. Lang, R. McKay, J. McKenney, G. Netto, D. Penson, J. Pow-Sang, R. Reiter, Sylvia S. Richey, Mack Roach Iii, Stan Rosenfeld, A. Shabsigh, D. Spratt, Benjamin A. Teply, J. Tward, Dorothy Shead, Deborah A. Freedman-Cass   +31 more
semanticscholar   +1 more source

Cellular Adaptation to VEGF-Targeted Antiangiogenic Therapy Induces Evasive Resistance by Overproduction of Alternative Endothelial Cell Growth Factors in Renal Cell Carcinoma

Neoplasia: An International Journal for Oncology Research, 2015
Vascular endothelial growth factor (VEGF)–targeted antiangiogenic therapy significantly inhibits the growth of clear cell renal cell carcinoma (RCC).
Kyung Seok Han, Peter A. Raven, Sebastian Frees, Kilian Gust, Ladan Fazli, Susan Ettinger, Sung Joon Hong, Cristian Kollmannsberger, Martin E. Gleave, Alan I. So   +9 more
doaj   +1 more source

Initial Longitudinal Outcomes of Risk-Stratified Men in Their Forties Screened for Prostate Cancer Following Implementation of a Baseline Prostate-Specific Antigen

The World Journal of Men's Health, 2023
Purpose: Prostate cancer (PCa) screening can lead to potential over-diagnosis/over-treatment of indolent cancers. There is a need to optimize practices to better risk-stratify patients.
Zoe D. Michael, Srinath Kotamarti, Rohith Arcot, Kostantinos Morris, Anand Shah, John Anderson, Andrew J. Armstrong, Rajan T. Gupta, Steven Patierno, Nadine J. Barrett, Daniel J. George, Glenn M. Preminger, Judd W. Moul, Kevin C. Oeffinger, Kevin Shah, Thomas J. Polascik   +15 more
doaj   +1 more source

Two-year quality of life after robot-assisted radical prostatectomy according to pentafecta criteria and cancer of the prostate risk assessment (CAPRA-S)

Scientific Reports, 2022
The quality of life (QoL) of men with optimal outcomes after robot-assisted radical prostatectomy (RARP) is largely unexplored. Thus we assessed meaningful changes of QoL measured with the EORTC QLQ-C30 24 months after RARP according to postsurgical ...
Theodoros Karagiotis, Jorn H. Witt, Thomas Jankowski, Mikolaj Mendrek, Christian Wagner, Andreas Schuette, Nikolaos Liakos, Pawel Rachubinski, Katarina Urbanova, Matthias Oelke, Mykyta Kachanov, Sami-Ramzi Leyh-Bannurah   +11 more
doaj   +1 more source