Results 11 to 20 of about 804,092 (296)

Prostatitis [PDF]

open access: yesCanadian Urological Association Journal, 2001
Prostatitis is a common condition that accounts for a significant number of visits to both the emergency department and the urologist. The precise pathogenic mechanism of prostatitis is not known. The most prevalent theory is that reflux of urine from the urethra into the intraprostatic ducts promotes ascending infection and leads to chemical or ...
W E, Lummus, I, Thompson
  +9 more sources

Androgen receptor (AR) antagonism triggers acute succinate‐mediated adaptive responses to reactivate AR signaling

open access: yesEMBO Molecular Medicine, 2021
Treatment‐induced adaptive pathways converge to support androgen receptor (AR) reactivation and emergence of castration‐resistant prostate cancer (PCa) after AR pathway inhibition (ARPI). We set out to explore poorly defined acute adaptive responses that
Neetu Saxena   +15 more
doaj   +1 more source

Translating the prostate cancer survivorship essentials framework into clinical practice: a participatory research process analysis

open access: yesCancer Survivorship Research & Care, 2023
Purpose: Accessible cancer survivorship care is a key tenet of quality cancer care. However, prostate cancer survivorship care is often fragmented with best practice models of care largely undefined. The Prostate Cancer Survivorship Essentials Framework (
Nicole Heneka   +10 more
doaj   +1 more source

Examining the influence of illness perception and financial toxicity on the quality of life of prostate cancer patients

open access: yesAfrican Journal of Urology, 2021
Background Cancer of the prostate (CaP) is a public health problem that affects the male genitourinary system causing a significant threat to men’s quality of life (QoL).
Elizabeth O. Akin-Odanye   +5 more
doaj   +1 more source

Dependency of Tamoxifen Sensitive and Resistant ER+ Breast Cancer Cells on Semaphorin 3C (SEMA3C) for Growth

open access: yesCells, 2023
Estrogen receptor positive (ER+) breast cancer (BCa) accounts for the highest proportion of breast cancer-related deaths. While endocrine therapy is highly effective for this subpopulation, endocrine resistance remains a major challenge and the ...
Satyam Bhasin   +6 more
doaj   +1 more source

The diagnostic accuracy of multiparametric MRI for detection and localization of prostate cancer depends on the affected region

open access: yesBJUI Compass, 2021
Objectives To determine the diagnostic accuracy of 3T multiparametric magnetic resonance imaging (mpMRI) for detecting and locating prostate cancer (PCa) on Dickinson's 27‐sector map, using histopathology specimens from radical prostatectomy (RP) as the ...
Martina Martins   +8 more
doaj   +1 more source

BAP1 haploinsufficiency predicts a distinct immunogenic class of malignant peritoneal mesothelioma

open access: yesGenome Medicine, 2019
Background Malignant peritoneal mesothelioma (PeM) is a rare and fatal cancer that originates from the peritoneal lining of the abdomen. Standard treatment of PeM is limited to cytoreductive surgery and/or chemotherapy, and no effective targeted ...
Raunak Shrestha   +32 more
doaj   +1 more source

The relationship between biochemical recurrence and number of lymph nodes removed during surgery for localized prostate cancer

open access: yesBMC Urology, 2023
Purpose To assess whether completeness of pelvic lymph node dissection (PLND) as measured by lymph node yield reduces biochemical recurrence (BCR) in men undergoing radical prostatectomy (RP) for prostate cancer (PCa), stratified according to Briganti ...
Paul Doan   +13 more
doaj   +1 more source

Prostatitis [PDF]

open access: yesHospital Medicine, 1999
Prostatitis, especially chronic prostatitis, is sometimes regarded as an obscure, ill-defined condition, perhaps because the anatomical location of the gland and ill-defined symptoms make diagnosis difficult. Treatment may appear time consuming and tiresome for doctor and patient, but by following established principles, diagnosis is often simple and ...
Ch, Theodorou, Th, Becopoulos
openaire   +4 more sources

SEMA3C drives cancer growth by transactivating multiple receptor tyrosine kinases via Plexin B1

open access: yesEMBO Molecular Medicine, 2018
Growth factor receptor tyrosine kinase (RTK) pathway activation is a key mechanism for mediating cancer growth, survival, and treatment resistance. Cognate ligands play crucial roles in autocrine or paracrine stimulation of these RTK pathways.
James W Peacock   +24 more
doaj   +1 more source

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