Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary +5 more
wiley +1 more source
Diagnostic accuracy of prostate-specific antigen and prostate-specific antigen density in patients suspected of having prostate cancer in South Korea: A large, multi-institutional registry. [PDF]
Yun JE +8 more
europepmc +1 more source
Implantable electrochemical sensors for continuous blood monitoring
Implantable electrochemical sensors enable direct, in situ, and continuous blood monitoring, shifting diagnosis from population‐based averages to dynamic, individualized analysis. This review systematically examines the influence of the unique blood properties on sensor design.
Kuangyi Zou +3 more
wiley +1 more source
Integrating Prostate-Specific Antigen Density With Magnetic Resonance Imaging (MRI) Likert Scoring to Minimize Overdiagnosis: A Retrospective Cohort Study at Blackpool Teaching Hospitals. [PDF]
Khalil W, Sheikh M, Rao P, Islam JU.
europepmc +1 more source
Stratifying the initial prostate cancer suspicion to avoid magnetic resonance exams by sequencing men according to serum prostate-specific antigen, digital rectal examination and the prostate-specific antigen density based on digital rectal prostate volume category. [PDF]
Morote J +5 more
europepmc +1 more source
Illuminating point‐of‐care diagnostics with aggregation‐induced emission biosensors
This review highlights the application of aggregation‐induced emission luminogens (AIEgens) in point‐of‐care (POC) diagnostics for disease biomarker detection. It systematically examines a range of biosensing platforms, including lateral flow immunoassays, microfluidic chips, and electrochemiluminescence sensors, alongside their utility in detecting ...
Danni Hu +3 more
wiley +1 more source
Association of Prostate Imaging Reporting and Data System (PI-RADS) Score and Prostate-Specific Antigen Density (PSAD) With Prostate Biopsy Histology Outcomes: A Retrospective Study. [PDF]
Balasubaramaniam V +8 more
europepmc +1 more source
An independent practice validation of the Prostate Imaging Reporting and Data System version 2 scoring system and the introduction of PDP (prostate-specific antigen density × PI-RADSv2) score to assist with further risk assessment. [PDF]
Patel PU, Bock D, Hettinger CA.
europepmc +1 more source
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley +1 more source
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia +4 more
wiley +1 more source

