Results 211 to 220 of about 91,007 (250)

Mapping the Radiopharmaceutical Therapy Landscape for Prostate Cancer: Insights Into Global Clinical Trial Trends and Future Directions

Med Research, EarlyView.
Zhiwu Dong, Sixiang Yan, Xiaodong Liu, Peng Gu   +3 more
wiley   +1 more source

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Prostate specific antigen and prostate specific antigen density. Roles in patient evaluation and management

Cancer, 1994
Prostate specific antigen (PSA) is the most accurate serum marker for prostate cancer. However, sensitivity and specificity are suboptimal, especially at the intermediate levels between 4.1 and 10.0 ng/ml (monoclonal). For intermediate PSA levels, PSA density (PSAD) provides unique information regarding the need for biopsy and the likelihood of ...
Mitchell C Benson, Carl A Olsson
exaly   +3 more sources

The use of prostate specific antigen density to improve the sensitivity of prostate specific antigen in detecting prostate carcinoma

Cancer, 1994
Prostate specific antigen (PSA) is useful as a tumor marker for monitoring patients with prostate cancer after definitive therapy. Limitations have been noted when PSA was used for the early detection of prostate cancer. The use of prostate specific antigen density [PSAD = PSA (ng/ml)/prostate volume (cc)] has been suggested to differentiate benign ...
W P Evans
exaly   +3 more sources

The Performance of Prostate Specific Antigen, Prostate Specific Antigen Density and Transition Zone Density in the Era of Extended Biopsy Schemes

Journal of Urology, 2008
Prostate specific antigen, prostate specific antigen density and transition zone density have been previously identified as prostate cancer detection tools. Recent studies suggest that prostate specific antigen may be increasingly accurate for detecting clinically significant high grade prostate cancer (Gleason grade 7 or greater).
Christopher S Elliott, Rajesh Shinghal
exaly   +3 more sources

Prostate Specific Antigen Density Correlates With Features of Prostate Cancer Aggressiveness

Journal of Urology, 2007
An increased prostate specific antigen density (serum prostate specific antigen divided by prostate volume) is an established parameter to help determine the need to perform prostate biopsies. A man with a high prostate specific antigen and a normal size prostate gland is more likely to have cancer than a man with the same prostate specific antigen and
Shilajit D Kundu, Kimberly A Roehl, Jo Ann V Antenor   +2 more
exaly   +3 more sources

Prostate specific antigen density in patients with histologically proven prostate carcinoma

Cancer, 1994
Prostate specific antigen (PSA) does not appear to have the specificity to distinguish between benign prostate hyperplasia and cancer when the PSA is low. PSA density is thought by many to improve the specificity for cancer; however, this theory remains controversial.The authors retrospectively reviewed 220 carcinomas in radical prostatectomy specimens
Gary J Miller, E David Crawford, E D Crawford   +2 more
exaly   +3 more sources

PROSTATE-SPECIFIC ANTIGEN DENSITY

Urologic Clinics of North America, 1997
Nearly 20 years have passed since PSA was definitively identified. Throughout this period, its clinical application as a tumor marker has expanded significantly. Today, besides monitoring prostate cancer therapy, PSA is being used extensively in mass screening programs for early detection of adenocarcinoma of the prostate and has become the most ...
M C, Beduschi, J E, Oesterling
openaire   +2 more sources

Correlation of prostate-specific antigen and prostate-specific antigen density with outcome of prostate biopsy

Urology, 1994
We attempt to correlate prebiopsy serum prostate-specific antigen (PSA) concentration and prostate-specific antigen density (PSAD) with histologic results of prostate biopsy.Sixty-two consecutive patients underwent prostate biopsy because of elevated PSA greater than 4 ng/mL and/or abnormal findings on digital rectal examination (DRE).
R, Bare, L, Hart, D L, McCullough
openaire   +2 more sources

Comparison of Prostate Specific Antigen with Prostate Specific Antigen Density for 3 Clinical Applications

Journal of Urology, 1994
We compared prostate specific antigen (PSA) to PSA density for 3 clinical uses: detection of nonpalpable prostate cancer, staging of clinically localized prostate cancer and prediction of PSA detectability following radical prostatectomy. Of 153 men with normal digital rectal examinations undergoing prostate biopsy 25% had prostate cancer.
K, Shinohara, J S, Wolf, P, Narayan, P R, Carroll   +3 more
openaire   +2 more sources

An algorithm for prostate cancer detection in a patient population using prostate-specific antigen and prostate-specific antigen density

World Journal of Urology, 1993
Prostate-specific antigen (PSA) is the most accurate serum marker for cancer of the prostate (CaP). However, its sensitivity and specificity are suboptimal, especially at values ranging between 4.1 and 10.0 ng/ml (monoclonal), because benign prostatic hypertrophy and hyperplasia (BPH) and CaP frequently coexist in this range.
M C, Benson, D J, McMahon, W H, Cooner, C A, Olsson   +3 more
openaire   +2 more sources