Results 81 to 90 of about 207,050 (299)

Editor’s Pick: PSMA-Specific Ligands in Prostate Cancer Diagnosis and Therapy [PDF]

open access: yesEuropean Medical Journal Urology, 2016
Prostate-specific membrane antigen (PSMA) is the most extensively studied biomarker and antigen of prostate cancer. It is overexpressed in almost all prostate cancers, and the expression level increases with prostate cancer progression.
Wei Jin, Ashutosh Barve, Kun Cheng
doaj  

Seminal Plasma Proteins [PDF]

open access: yes, 2012
The ejaculated semen consists of two major components viz. sperm cells (spermatozoa) and the fluid part obtained after centrifugation called seminal plasma.
P Perumal
core   +2 more sources

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

open access: yesAdvanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang   +10 more
wiley   +1 more source

Human prostate sphere-forming cells represent a subset of basal epithelial cells capable of glandular regeneration in vivo. [PDF]

open access: yes, 2009
BackgroundProstate stem/progenitor cells function in glandular development and maintenance. They may be targets for tumor initiation, so characterization of these cells may have therapeutic implications.
Garraway, Isla P   +11 more
core   +1 more source

Phase Separation of NFIB Suppresses SLC3A2‐Mediated Ferroptosis in Castration‐Resistant Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Castration‐resistant prostate cancer (CRPC) remains sensitive to ferroptosis, but its intrinsic resistance is poorly understood. Here, we identify NFIB as a master suppressor. SIRT7‐mediated NFIB acetylation drives its liquid–liquid phase separation, which promotes SLC3A2 transcription to inhibit ferroptosis.
Qiunuo Li   +11 more
wiley   +1 more source

Practice patterns and outcomes of equivocal bone scans for patients with castration-resistant prostate cancer: Results from SEARCH. [PDF]

open access: yes, 2019
ObjectiveTo review follow-up imaging after equivocal bone scans in men with castration resistant prostate cancer (CRPC) and examine the characteristics of equivocal bone scans that are associated with positive follow-up imaging.MethodsWe identified 639 ...
Amling, Christopher L   +9 more
core   +1 more source

Identification and validation of targets for cancer immunotherapy: from the bench-to-bedside [PDF]

open access: yes, 2013
Chapter 12 in Novel Gene Therapy ...
Brooks, Suzanne E.   +4 more
core   +3 more sources

An Artificial Antibody‐Based Toolbox Accelerates Validation of Hidden Microproteins Encoded by the Dark Genome

open access: yesAdvanced Science, EarlyView.
Microproteins are hidden treasures encoded by the “dark proteome” but remain largely underexplored due to the lack of highly efficient tools. We developed a molecularly imprinted polymers (MIPs)‐based toolbox (CLAIMID) to achieve accelerated and ultrasensitive microproteins validation at multiple biological scales (single living cells, cell populations,
Hui He   +10 more
wiley   +1 more source

Renal-type clear cell carcinoma of prostate: A case report and review of literature

open access: yesIndian Journal of Pathology and Microbiology, 2018
We analyzed the clinicopathological features of renal-type clear cell carcinoma (RTCCC) in the prostate and its diagnosis according to the example in our hospital and review of the literature.
Guangjie Liao   +5 more
doaj   +1 more source

Beyond the immune suppression: the immunotherapy in prostate cancer [PDF]

open access: yes, 2015
Prostate cancer (PCa) is the second most common cancer in men.Aswell in many other human cancers, inflammation and immune suppression have an important role in their development.We briefly describe the host components that interact with the tumor to ...
Agliano', Anna Maria   +4 more
core   +3 more sources

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