Results 171 to 180 of about 75,257 (296)

Possible Role of Diffusion-Weighted Imaging in Prediction of Prostate Cancer Grade Group Upgrading: Insights from Biopsy to Radical Prostatectomy. [PDF]

Medicina (Kaunas)
Żurowska A, Skrobisz K, Sowa M, Pęksa R, Panas D, Grzywińska M, Matuszewski M, Szurowska E.   +7 more
europepmc   +1 more source

Single‐Cell and Spatial Transcriptomics Uncover Immune Dynamics and Cellular Heterogeneity in Benign Prostatic Hyperplasia and Prostate Cancer Transition

MedComm, Volume 7, Issue 6, June 2026.
Leveraging integrated single‐cell and spatial transcriptomics, we delineated the sustained immunosuppressive landscape during prostate disease progression. Based on this, we have developed a precise gene‐based diagnostic classifier and a multimodal prognostic model.
Yuanyuan Luo, Haitao Zhong, Tongrui Shang, Bin Hu, Dongbo Yuan, Xueyuan Jia, Ruichong Lin, Zehua Wang, Yinyi Fang, Guohua Zhu, Jukun Song, Zhangcheng Liu, Bo Yan, Fa Sun, Zhenyu Jia, Yunfang Yu, Luhui Mao, Hai Huang, Jianguo Zhu   +18 more
wiley   +1 more source

The evolution of radical prostatectomy: a scoping review on surgical techniques and integration of surgeon-assisting concepts into the surgical workflow. [PDF]

Front Surg
Nick P, Tokas T, Guven S, Kallidonis P, Barret E, Ballesta Martínez B, Ismail Abdelrahman MF, Gallioli A, Nagele U, Ortner G.   +9 more
europepmc   +1 more source

A Pilot Study of 18F‐rhPSMA‐7.3‐PET/MRI to Reduce Mischaracterization of Active Surveillance and Focal Therapy Candidates With Occult Higher Risk Disease

The Prostate, Volume 86, Issue 8, Page 865-871, June 2026.
ABSTRACT Introduction PSMA‐PET offers an opportunity to reduce the mischaracterization of disease in active surveillance (AS) and focal therapy (FT) candidates. We describe the results of a pilot clinical trial evaluating 18F‐radiohybrid(rh)PSMA‐7.3‐PET/MRI to detect occult adverse pathology among potential AS and FT candidates (NCT05852041).
Ridwan Alam, Derek Hesse, Nikki Hubbard, Emma McGarrity, Sai Kumar, Clayton Neill, Yutai Li, Nicole Handa, Hiten D. Patel, Edward M. Schaeffer, Hatice Savas, Ashley E. Ross   +11 more
wiley   +1 more source

MRI radiomics predicting cribriform growth informs active surveillance decision in intermediate-risk prostate cancer. [PDF]

Eur Radiol Exp
Fernandez Salamanca M, Simões R, Deręgowska-Cylke M, Pais Pooch E, van Leeuwen PJ, van der Poel HG, Guimaraes MAS, van der Heide UA, Schoots IG.   +8 more
europepmc   +1 more source

A Feasibility Study of the Repurposing of Prazosin to Improve Treatment Outcomes in Men Receiving Radiotherapy for Prostate Cancer (MiniRaP‐00)

The Prostate, Volume 86, Issue 8, Page 891-899, June 2026.
ABSTRACT Background Further work is needed to improve treatment outcomes for prostate cancer (PCa), with the repurposing of the α1‐adrenoreceptor antagonists presenting a potential solution. This feasibility clinical trial presents the first prospective data of the use of an α1‐adrenoreceptor antagonist in men undergoing radiotherapy for PCa.
Liam D. King, David Christie, Daniel Cehic, Wendy Dare, Russ Chess‐Williams, Donna Sellers, Catherine McDermott, Alexandra McCarthy, Shailendra Anoopkumar‐Dukie   +8 more
wiley   +1 more source

Understanding randomized controlled trial generalizability through an embedded molecular diagnostics trial. [PDF]

JNCI Cancer Spectr
Lewicki P, Srivastava A, Jiang R, Johnson A, Ghani K, Ginsburg K, Borza T, Stensland K, Salami SS, Davicioni E, Dunn RL, Daignault-Newton S, Palapattu GS, Spratt DE, Cher M, Schipper M, Dess RT, Morgan TM, Singhal U.   +18 more
europepmc   +1 more source

Is Saturation Biopsy Still a Viable Alternative to Fusion Biopsy in the Era of Multiparametric MRI? A Comparative Analysis in Patients With Prior Negative Biopsy

The Prostate, Volume 86, Issue 9, Page 990-996, June 15, 2026.
ABSTRACT Background We aimed to compare the diagnostic accuracy of transrectal ultrasound (TRUS)‐guided saturation biopsy (SB) and multiparametric MRI (mpMRI)‐TRUS fusion‐guided combined biopsy (CB) in patients with prior negative prostate biopsies. Methods We retrospectively analyzed data from 160 patients who underwent transrectal prostate biopsy ...
Arda Taşkın Taşkıran, Yusuf Şenoğlu   +1 more
wiley   +1 more source

Perineal Prostatectomy

International Journal of Clinical Practice, 1973
openaire   +2 more sources

Castration Resistance Accelerates Prostate Cancer Kinetics

The Prostate, Volume 86, Issue 9, Page 1021-1027, June 15, 2026.
ABSTRACT Background Prostate cancer can be an indolent disease with which patients can live for many years. Thus, an understanding of how therapy and its ensuing resistance affect prostate cancer kinetics may guide efforts to determine optimal timing of therapy initiation.
Sheila Jonnatan, Luka Cavka, Angelo M. De Marzo, Samuel R. Denmeade, Mark C. Markowski, Emmanuel S. Antonarakis, Bruce J. Trock, Catherine H. Marshall, Ravi A. Madan, David J. Einstein, Laura A. Sena   +10 more
wiley   +1 more source