Results 161 to 170 of about 75,257 (296)

The first United States prospective trial using the Hugo™ robot‐assisted surgery system

open access: yesBJU International, Volume 138, Issue 1, Page 85-91, July 2026.
Objective To describe the safety and effectiveness of the Hugo™ robot‐assisted surgery (RAS) system (Medtronic, Minneapolis, MN, USA) when used for three urological procedures. Patients and Methods The Expand URO (ClinicalTrials.gov identifier: NCT05696444) was the first investigational study for the Hugo RAS system based in the United States. It was a
Michael R. Abern   +14 more
wiley   +1 more source

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, Volume 20, Issue 6, Page 1429-1452, June 2026.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Combined robot-assisted simple prostatectomy and laparoscopic nephrectomy: a case series. [PDF]

open access: yesJ Med Case Rep
Khanmammadova N   +10 more
europepmc   +1 more source

Hepatocyte growth factor/c‐Met signaling axis in human diseases: Mechanistic insights and therapeutic potential

open access: yesJournal of Cell Communication and Signaling, Volume 20, Issue 2, June 2026.
Figure 1 visually summarizes the core biological functions and therapeutic potential of the HGF/c‐Met signaling axis. Abstract Hepatocyte growth factor (HGF) is a multifunctional cytokine that activates the tyrosine kinase activity of its specific receptor, c‐Met (mesenchymal–epithelial transition factor).
Hongqin Sun   +7 more
wiley   +1 more source

Testosterone and docetaxel treatment effect on mortality risk in nonmetastatic high‐risk prostate cancer: A predictive biomarker analysis

open access: yesCancer, Volume 132, Issue 11, 1 June 2026.
Abstract Background Prostate cancer (PC) arising in patients with low testosterone is often more aggressive and less responsive to androgen deprivation therapy (ADT). This study evaluated whether baseline testosterone group (low vs. normal) modifies the mortality benefit of adding docetaxel to radiation therapy (RT) and ADT in nonmetastatic high‐risk ...
Johnathan Zeng   +7 more
wiley   +1 more source

Dynamic Profiling of Circulating Tumor Cells and MYC/PTEN Alterations in Prostate Cancer Patients Undergoing Radical Prostatectomy in Amazon Population

open access: yesMolecular Carcinogenesis, Volume 65, Issue 6, Page 665-676, June 2026.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed malignancy among men and the sixth leading cause of cancer‐related mortality worldwide. Radical prostatectomy remains the standard treatment for localized disease; however, approximately one‐third of patients develop biochemical recurrence within 10 years. Although prostate‐specific
Juliana Ramos Chaves   +7 more
wiley   +1 more source

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