Results 161 to 170 of about 82,034 (275)

A Simple Cell Culture Assay for Human Prostatic Branching Morphogenesis Spotlights Bone Morphogenetic Protein Signaling as a Therapeutic Target in Benign Prostatic Hyperplasia

The Prostate, Volume 86, Issue 13, Page 1332-1340, September 15, 2026.
ABSTRACT Background Benign prostatic hyperplasia (BPH) leads to prostate enlargement and lower urinary tract symptoms that can resist treatment. A histologic hallmark of BPH is glandular epithelial hyperplasia with new ductal branching morphogenesis. The stromal inductive factors driving tissue morphogenesis may provide new therapeutic targets, but are
Anna S. Pollack, James D. Brooks, Jonathan R. Pollack   +2 more
wiley   +1 more source

Editorial Comment to Validation of the NCCN Subclassification for Intermediate-Risk Prostate Cancer in a Japanese Radical Prostatectomy Cohort: Results From the MICAN Study. [PDF]

Int J Urol
Kobayashi S.
europepmc   +1 more source

Years of Life Lost in Incidental Prostate Cancer

The Prostate, Volume 86, Issue 13, Page 1375-1381, September 15, 2026.
ABSTRACT Background It is unknown how survival is prematurely curtailed by incidental prostate cancer (IPCa). We aimed to quantify the average years of life lost (YLL) due to IPCa. Methods Within the SEER database 2004–2021, IPCa patients aged 45–75 were identified.
Fabian Falkenbach, Mattia Longoni, Andrea Marmiroli, Quynh Chi Le, Calogero Catanzaro, Michele Nicolazzini, Federico Polverino, Jordan A. Goyal, Riccardo Schiavina, Alessandro Volpe, Gennaro Musi, Felix K. H. Chun, Alberto Briganti, Francesco Montorsi, Fred Saad, Shahrokh F. Shariat, Lars Budäus, Markus Graefen, Pierre I. Karakiewicz   +18 more
wiley   +1 more source

Artificial Intelligence in Patient Education: ChatGPT for Penile Prosthesis Surgery Counseling, a Likert Scale Analysis

Andrology, Volume 14, Issue 6, Page 1684-1700, September 2026.
ABSTRACT Introduction Erectile dysfunction (ED) significantly impacts quality of life. For patients unresponsive to conservative treatments, penile prosthesis implantation represents an effective solution with high satisfaction rates. However, the complexity and sensitive nature of the procedure often generate multiple patient concerns.
Gabriele Tulone, Nicola Pavan, Rosa Giaimo, Alchiede Franco Simonato, Alfonzo Salzano, Davide Cosentino, Francesco Claps, Alchiede Simonato   +7 more
wiley   +1 more source

Retrograde robot-assisted radical prostatectomy in a patient with localized prostate cancer: a case report. [PDF]

Front Surg
Harizanova Z, Ahmed-Popova F, Pavlov V, Bozhikova E.   +3 more
europepmc   +1 more source

Expanding the Taxonomy of Ethical Issues in Surgical Innovation

Bioethics, Volume 40, Issue 7, Page 679-687, September 2026.
ABSTRACT Surgical innovation poses significant ethical challenges. Previous work has grouped these challenges under four categories: potential harms to patients; compromised informed consent; unfair allocation of healthcare resources; and conflicts of interest. We argue that recent technological developments in surgery warrant the addition of three new
Jane Johnson, Katrina Hutchison, Wendy Rogers   +2 more
wiley   +1 more source

Intermediate clinical endpoints as surrogates for overall survival after salvage prostatectomy

BJU International, Volume 138, Issue 3, Page 430-437, September 2026.
Objectives To evaluate biochemical recurrence‐free survival (BRFS) and metastasis‐free survival (MFS) as potential intermediate clinical endpoints (ICEs) for overall survival (OS) in patients undergoing salvage radical prostatectomy (sRP). Patients and Methods Evaluable patients were selected from a retrospective dataset, resulting in a cohort of 879 ...
Navid Roessler, Zuzanna Nowicka, Marcin Miszczyk, Giorgio Calleris, Alessandro Dematteis, Malte W. Vetterlein, Simone Albisinni, Henk G Van Der Poel, Paul Cathcart, Giovanni E. Cacciamani, Inderbir S. Gill, Raj A. Persad, Steven Joniau, Rafael Sanchez‐Salas, Joseph A. Smith Jr, Robert Jeffrey Karnes, Mohamed E. Ahmed, Pawel Rajwa, Derya Tilki, Shahrokh F. Shariat, Paolo Gontero, Giancarlo Marra, on behalf of the Young Academic Urologists Prostate Cancer Working Party   +22 more
wiley   +1 more source

Validation of the NCCN Subclassification for Intermediate-Risk Prostate Cancer in a Japanese Radical Prostatectomy Cohort: Results From the MICAN Study. [PDF]

Int J Urol
Oono T, Terashita M, Mori S, Oka A, Matsuzaki S, Yano A, Matsumura M, Ninomiya I, Shinomori K, Ogawa T, Onishi T, Shirato A, Watanabe Y, Hashine K, Yamashita N, Watanabe R, Miura N, Saika T.   +17 more
europepmc   +1 more source

Spatial transcriptomics reveals clonal relationships between intraductal carcinoma and adjacent invasive prostate cancer

Histopathology, Volume 89, Issue 3, Page 429-441, September 2026.
Spatial transcriptomics of six prostate samples reveals a close clonal relationship between high‐grade Prostatic Intraepithelial Neoplasia (HGPIN), Intraductal carcinoma (IDC) and adjacent invasive glands. In three samples, adjacent invasive glands had more copy number variants than HGPIN and IDC. Adjacent invasive glands were also placed at the end of
Hridya Harikumar, Myrthe de Waard‐van Baardwijk, Marit de Haan, Gregory van Beek, Karishma Lila, Martin E van Royen, Thierry PP van den Bosch, Mathijs A Sanders, Eric Bindels, Andrew Stubbs, Geert JLH van Leenders   +10 more
wiley   +1 more source

De-escalation surgery for localized prostate cancer: rationale and future direction of precision prostatectomy. [PDF]

Curr Opin Urol
Franke J, Rogers CG, Zuluaga L, Badani K, Menon M.   +4 more
europepmc   +1 more source