Results 161 to 170 of about 2,211,291 (297)

Spatiotemporal Multi‐Omic Mapping Reveals Liver‐Muscle Metabolic Crosstalk in Cancer Cachexia

Advanced Science, EarlyView.
The interactive CCAtlas platform delineates cross‐species, spatiotemporal, and sex‐specific molecular dynamics and metabolic rewiring across organs during cancer cachexia. Hepatic Gamt downregulation curtails hepatic creatine synthesis to trigger systemic creatine insufficiency and consequent skeletal muscle atrophy in LLC tumour‐bearing mice ...
Zihan Tian, Qianyu Wang, Wenyan Gao, Xianfeng Li, Jiawen Fan, Xiaoliang Wu, Siqi Liu, Xiangdong Ming, Danna Yeerken, Mutian Shen, Qingjie Min, Qimin Zhan, Yan Wang   +12 more
wiley   +1 more source

Prostatic diseases in transgender women: A systematic review of diagnosis, risk, and management. [PDF]

Int J Transgend Health
Bourillon A, Guillot-Tantay C, Freton L, Zhao L, Mesnard B, Morel-Journel N, Mathieu R, Neuville P, Schirmann A, Peyronnet B, Madec FX.   +10 more
europepmc   +1 more source

Characterization a model of prostatic diseases and obstructive voiding induced by sex hormone imbalance in the Wistar and Noble rats. [PDF]

Transl Androl Urol, 2019
Konkol Y, Vuorikoski H, Streng T, Tuomela J, Bernoulli J.   +4 more
europepmc   +1 more source

DLST Succinylation‐Mediated Mitochondrial Metabolic Remodeling and Cuproptosis Resistance Promote Malignant Progression of Lung Adenocarcinoma

Advanced Science, EarlyView.
The DLST K409 succinylation mediated by CPT1A promotes OXPHOS and redox homeostasis through regulating enzyme activity, thereby promoting the malignant progression of LUAD. Notably, the succinylation of DLST can enhance the cuproptosis resistance by inhibiting its lipoylation.
Xuanxuan Li, Peijun Zhou, Xingzhi Peng, Qixin Liu, Wenhui Zeng, Rui Wang, Liangfang Shen, Jinwu Peng, Qin Zhou, Lifang Yang   +9 more
wiley   +1 more source

Association between two single nucleotide polymorphisms of the Prostaglandin-Endoperoxide Synthase 1 and 2 genes and cell proliferative prostatic diseases in Lebanon. [PDF]

Oncotarget
Sheehan BJ, Edwards B, Medrano IS, El-Saidi MA, Zaidan WR, El-Ezzi AA, Kuddus RH.   +6 more
europepmc   +1 more source

Fatigue, depression, and quality of life in patients with prostatic diseases. [PDF]

Cent European J Urol, 2017
Engl T, Drescher D, Bickeböller R, Grabhorn R.   +3 more
europepmc   +1 more source

Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy

Advanced Science, EarlyView.
Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao, Markus Isfeld Diehl, Caroline N. Jones   +2 more
wiley   +1 more source

Causal relationship between prostatic diseases and prostate cancer: a mendelian randomization study. [PDF]

BMC Cancer
Huang J, Sun J, Wang K, Zheng L, Fan Y, Qian B.   +5 more
europepmc   +1 more source

Histopathological Spectrum of Prostatic Diseases

, 2015
Prostatic lesions are a common presenting problem in men. Benign prostatic hyperplasia (BPH) and carcinoma prostate are increasingly frequent with advancing age especially after forty years.
Ajay Kumar Arora, Ranjan Agrawal and Parbodh Kumar
core  

Dual‐Target Nectin‐4/FAP Heterobivalent Probe 68Ga/177Lu‐FZ‐NF‐1 for Triple‐Negative Breast Cancer: Preclinical Theranostic Evaluation and First‐in‐Human Translation

Advanced Science, EarlyView.
A novel hetero‐bivalent agent, 68Ga/177Lu‐FZ‐NF‐1, concurrently targets Nectin‐4 and FAP in triple‐negative breast cancer. It yields significant preclinical tumor regression and clinically identifies additional metastatic lesions missed by 18F‐FDG PET, demonstrating promising theranostic potential for personalized management.
Ye Li, Li Sun, Xiaoyu Pan, Shuyi Lin, Dongliang Wang, Jianping Zhang, Fengshuang Qiu, Bin Zhu, Lingzhou Zhao, Fengsheng Zhang, Liyan Bai, Bingxin Gu, Xiaoping Xu, Shaoli Song   +13 more
wiley   +1 more source