Results 31 to 40 of about 10,722,374 (289)
The Multifaceted Role of Osteopontin in Prostate Pathologies
Biomedicines, 2023 The prostate gland, located beneath the bladder and surrounding the proximal urethra in men, plays a vital role in reproductive physiology and sexual health. Despite its importance, the prostate is vulnerable to various pathologies, including prostatitis,
Samara V. Silver, Petra Popovics
doaj +1 more source
Nigerian Journal of Surgery, 2013 Aims and Objective: This study aims at correlating different digital rectal examination (DRE) abnormalities with histopathological results in patients with prostatic diseases.
R. Ojewola +4 more
semanticscholar +1 more source
Frequency and Trends of Prostatic Diseases in a Subset of Karachi Population: A Retrospective Study
Pakistan Journal of Medicine and DentistryBackground: Prostatic diseases are a leading cause of frequent urinary complaints in elderly males. The most common diseases include prostatitis, benign prostatic hyperplasia, and prostate cancer.
Asma Shabbir +6 more
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Recent advances in prostate development and links to prostatic diseases
Wiley Interdisciplinary Reviews: Systems Biology and Medicine, 2013 The prostate is a branched ductal‐acinar gland that is part of the male reproductive tract. Prostate development depends upon the integration of steroid hormone signals, paracrine interactions between the stromal and epithelial tissue layers, and the ...
Ginny L. Powers, Paul C. Marker
semanticscholar +1 more source
Looking to the metabolic landscapes for prostate health monitoring
Prostate International, 2017 Abnormal metabolism is a widely accepted biological signature of prostatic diseases, including prostate cancer and benign prostate hyperplasia. Recently accumulated epidemiological and experimental evidence illustrate that the metabolic syndrome ...
Wun-Jae Kim, Jayoung Kim
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Use of Epilobium parviflorum in the Treatment of Benign Prostatic Hyperplasia in Canines
Veterinary Medicine and ScienceThe objective of the study was to evaluate the effect of Epilobium parviflorum (EP) as a treatment for benign prostatic hyperplasia (BPH) in dogs based on two clinical case reports. Two dogs with BPH were treated for 2 months with EP extract.
Guillermo Cazzuli +5 more
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COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells
Molecular Oncology, EarlyView.This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos +6 more
wiley +1 more source
CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3
Molecular Oncology, EarlyView.PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh +12 more
wiley +1 more source
Molecular Oncology, EarlyView.Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau +8 more
wiley +1 more source