Results 121 to 130 of about 96,603 (330)

Aquablation for benign prostatic hyperplasia: real‐world prostate size relevance and bleeding events across 6 years

BJU International, EarlyView.
Objective To present large‐scale safety outcomes, with a particular focus on postoperative bleeding following Aquablation for benign prostatic hyperplasia. Patients and Methods Patients who underwent Aquablation between 2019 and 2024 across Asia, Europe, and North America were assessed to evaluate trends in treated prostate sizes, which were visualised
Mario Bitar, Roseanne Ferreira, Sagi Shprits, Omar Buksh, Naeem Bhojani, Bilal Chughtai, Kevin C. Zorn, Dean Elterman   +7 more
wiley   +1 more source

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source

Tumor‐Associated Macrophage‐Derived CXCL1 Promotes Endometrial Cancer Progression Through the CXCR2/NF‐κB Pathway

Cancer Science, EarlyView.
CXCL1 secreted by M2 macrophages induced EMT of EC cells through the CXCR2/NF‐κB pathway; CXCR2 expression was predominantly observed in the epithelial compartment, whereas CXCL1 expression was primarily localized in the stromal region; Neutralization of M2 macrophage‐secreted CXCL1 and inhibiting the NF‐κB pathway can inhibit EC progression in vivo ...
Ruiqi Xia, Dingtian Qi, Boshu Ji, Yisheng Dai, Xianchao Kong   +4 more
wiley   +1 more source

Serum sex steroids, gonadotrophins and sex hormone-binding globulin in prostatic hyperplasia

Annals of Saudi Medicine, 2008
Background: Benign prostatic hyperplasia (BPH) develops in elderly males when serum androgens are relatively lower than in healthy younger males, but it is not well understood whether and how sex steroids are altered in prostatic hyperplasia. It is also
Ansari Mohammad Abdul, Begum Dilruba, Islam Fakhrul   +2 more
doaj  

PERBEDAAN ANGKA KEJADIAN BENIGN PROSTATIC HYPERPLASIA PADA USIA ANTARA 50-59 TAHUN DENGAN USIA DIATAS 60 TAHUN PADA PEMERIKSAAN ULTRASONOGRAFI DI RS. PKU (PEMBINA KESEJAHTERAAN UMAT) MUHAMMADIYAH SURAKARTA [PDF]

, 2010
Farida kumala sari 2010. Perbedaan angka kejadian benign prostatic hyperplasia pada usia antara 50-59 tahun dengan usia diatas 60 tahun pada pemeriksaan ultrasonografi di RS. PKU (Pembina Kesejahteraan Umat) Muhammadiyah Surakarta.
SARI, FARIDA KUMALA
core  

Gene Expression Analysis of Patients with Prostate Cancer vs Benign Prostate Hyperplasia [PDF]

, 2022
Mahdi Saeedi
openalex   +1 more source

Targeting ROCK1/YAP1 Axis Ameliorates Inflammation‐Induced Prostatic Hyperplasia via Stabilising SIRT1‐Dependent Mitochondrial Dynamics

Cell Proliferation, EarlyView.
Prostate‐specific YAP1 overexpression induces pathological BPH phenogenesis. Targeting ROCK1/YAP1 with fasudil and verteporfin alleviates inflammatory BPH lesions. YAP1 orchestrates mitochondrial dysfunction and oxidative stress via suppressing SIRT1 function.
Dongxu Lin, Pengyu Wei, Mengyang Zhang, Kang Li, Lina Li, Zhipeng Li, Changcheng Luo, Wenbo Kuang, Kai Cui, Zhong Chen   +9 more
wiley   +1 more source

Behind the scenes: how the EMILIN/Multimerin family shapes the cancer landscape

The FEBS Journal, EarlyView.
The EMILIN/Multimerin family members regulate key hallmarks of cancer—including apoptosis, angiogenesis, metastasis, and tumor microenvironment remodeling. As indicated, their function in immune evasion, drug resistance, and metabolic reprogramming remains largely unexplored.
Evelina Poletto, Naike Casagrande, Emanuele Di Siena, Greta Carobolante, Lucrezia Camicia, Giorgia Schinello, Samanta Muzzin, Enrica Timis, Paola Spessotto, Maurizio Mongiat   +9 more
wiley   +1 more source

Ethanol Extract of Chaenomeles sinensis Inhibits the Development of Benign Prostatic Hyperplasia by Exhibiting Anti-oxidant and Anti-inflammatory Effects

, 2022
Jong-Su Kang, Xin Yi Zhao, Jeong Ho Lee, Jeong‐Sang Lee, Young‐Sam Keum   +4 more
openalex   +1 more source

Variable selection via thresholding

Scandinavian Journal of Statistics, EarlyView.
Abstract Variable selection comprises an important step in many modern statistical inference procedures. In the regression setting, when estimators cannot shrink irrelevant signals to zero, covariates without relationships to the response often manifest small but nonzero regression coefficients.
Ka Long Keith Ho, Hien Duy Nguyen
wiley   +1 more source