Results 121 to 130 of about 150,306 (248)

Neuropsychiatric Outcomes Associated With GLP‐1 Receptor Agonist Use in Medicare Beneficiaries With Type 2 Diabetes: Variation by Treatment Pattern and Obesity Status

Diabetes, Obesity and Metabolism, EarlyView.
ABSTRACT Aims Glucagon‐like peptide‐1 (GLP‐1) receptors are expressed in brain regions governing mood, reward and stress, yet the neuropsychiatric effects of GLP‐1 receptor agonist (GLP‐1 RA) therapy remain poorly characterized. We estimated associations between GLP‐1 RA use and neuropsychiatric disorders and variation by obesity status and treatment ...
Seo Hyon Baik, Fitsum Baye, Haotian Xian, Kin Wah Fung, Clement J. McDonald   +4 more
wiley   +1 more source

Prostatic hyperplasia in Italian mummies (XV-XIX century)

, 2011
We report three ancient cases of prostatic hyperplasia recently observed in natural and artificial mummies from central ...
GRAVINA GL, GIUFFRA, VALENTINA, MERCURIO C, VENTURA L, MARAMPON F, FORNACIARI, GINO   +5 more
core  

CD36‐mediated lipid rewiring in the metabolic adaptation of tumour ecosystems

The FEBS Journal, EarlyView.
Nutrient deprivation drives a lipid‐centric shift in tumour metabolic symbiosis and signalling network. CD36 functions as a bidirectional bridge, transferring fatty acids from stromal donors (adipocytes, CAFs) to the ecosystem tumour‐ and microenvironment‐dependently.
Anna Sebestyén, Viktória Varga, Fatime Szalai, Risa Miyaura, Nóra Förhécz, Bálint Csikós, Rebeka Gelencsér, Zsófia Gábriel, Timea Komlódi, Katalin Dezső, Ildikó Krencz, Dorottya Moldvai   +11 more
wiley   +1 more source

Analysis of Notch1 and Notch3 Signaling Pathway Components in Benign Prostatic Hyperplasia and Prostate Cancer Patients. [PDF]

J Clin Lab Anal
This study evaluates the association between Notch1 and Notch3 genetic variations and serum protein levels in patients with benign prostatic hyperplasia and prostate cancer. While genetic variations showed no significant link to disease risk, serum protein levels were significantly lower in prostate cancer and metastatic groups compared to healthy ...
Yagci E, Ozbayer C, Ozen A, Zengin G, Kurt H.   +4 more
europepmc   +2 more sources

A guide to transcriptional cyclin‐dependent kinases in cancer

The FEBS Journal, EarlyView.
Transcriptional cyclin‐dependent‐kinases (tCDKs) facilitate gene expression by promoting RNA polymerase II (RNAPII) progression through discrete phases of the transcription cycle. Aberrant tCDK activity is detectable in different human cancers, thereby contributing to de‐regulated gene expression programs that drive oncogenic phenotypes.
Jennifer R. Devlin, Salla Kyheröinen, Ricky W. Johnstone   +2 more
wiley   +1 more source

Ureteral: Prostatic Hyperplasia

, 1900
Prostatic hyperplasia with urethral obstruction and massive bladder hypertrophy and dilatation. Note the projecting median bar of the prostate which acted as a ball valve to obstruct the urethra (arrow).
MUSC Department of Pathology and Laboratory Medicine
core  

Learning Curve of Pentaspline Pulsed‐Field Ablation With Posterior Wall Isolation for Persistent Atrial Fibrillation

Journal of Cardiovascular Electrophysiology, EarlyView.
ABSTRACT Background Pentaspline pulsed‐field ablation (PFA) has emerged as a novel modality for pulmonary vein isolation (PVI) and posterior wall isolation (PWI) in persistent atrial fibrillation (AF). However, the learning curve associated with combined PVI + PWI and the contribution of anatomical factors to acute lesion completeness remain ...
Atsuhiko Yagishita, Kazuma Iimura, Aika Iijima, Mari Amino, Yuji Ikari, Koichiro Yoshioka   +5 more
wiley   +1 more source

Management and Treatment of Benign Prostatic Hyperplasia Symptoms: Current Insights [PDF]

Othmane Zekraoui,1 Naeem Bhojani,1,2 Kevin C Zorn,3 Dean Elterman,4 Bilal Chughtai5,6 1Faculty of Medicine, Université de Montréal, Montreal, QC, Canada; 2Division of Urology, Department of Surgery, Université de Montréal Health Center, Montreal, QC ...
Zorn KC, Chughtai B, Bhojani N, Elterman D, Zekraoui O   +4 more
core  

European S2k guidelines for hidradenitis suppurativa/acne inversa Part 1. Epidemiology, diagnosis and clinical assessment

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Updated S2k hidradenitis suppurativa (HS) guidelines provide expert consensus on diagnosis, assessment and comorbidities. Expanded substantially since the 2015 version, they reflect rapid growth in HS literature and aim to improve generalist‐level patient care through evidence‐informed, consensus‐based guidance.
G. B. E. Jemec, B. Villumsen, K. R. van Straalen, H. H. van der Zee, S. Valiukevičienė, T. Tzellos, J. C. Szepietowski, A. Szegedi, D. M. L. Saunte, M. Romanelli, H. Raynal, F. Prignano, E. P. Prens, M. Podda, A. Nassif, A. Molina‐Leyva, Ł. Matusiak, A. V. Marzano, B. M. McGrath, A. I. Liakou, B. Kirby, L. Kemény, E. Just, D. Ioannidis, J. R. Ingram, R. E. Hunger, B. Horváth, P. Guillem, Ø. Grimstad, E. J. Giamarellos‐Bourboulis, M. Dolenc‐Voljč, V. Del Marmol, Z. Bukvić Mokos, V. Bettoli, F. Benhadou, F. G. Bechara, C. C. Zouboulis   +36 more
wiley   +1 more source

Prevalence and Characteristics of Urinary Catheter Blockage in Patients With Long‐Term Urinary Catheterization: A Cross‐Sectional Study

Journal of Clinical Nursing, EarlyView.
ABSTRACT Aims To determine the prevalence and characteristics of urinary catheter blockage in older patients using objective indicators and to characterize obstructive materials and microbiota. Design A cross‐sectional study. Methods Patients aged ≥ 65 years with an indwelling catheter for ≥ 24 h were recruited from a long‐term care hospital.
Natsumi Hirose, Mao Kunimitsu, Chihiro Takizawa, Yukie Kataoka, Minami Shinkawa, Chika Takada, Atsuo Kawamoto, Jun Kamei, Haruki Kume, Chizuko Konya, Hiromi Sanada, Gojiro Nakagami   +11 more
wiley   +1 more source