Results 121 to 130 of about 52,757 (299)

Association Between FTO rs1558902 Polymorphism, Age‐Related Hypogonadism, and Central Obesity in Japanese Men

Andrology, EarlyView.
ABSTRACT Background Obesity and low testosterone levels are closely interconnected, with the FTO gene being the most robust genetic determinant of body mass index (BMI). However, whether this primary genetic driver of obesity directly influences the hypothalamic‐pituitary‐testicular (HPT) axis remains unclear.
Takahiro Tsutsumi, Hideyuki Okuma, Fuminori Kazama, Masumi Endo, Yuna Takato, Hitomi Nara, Asako Miyazaki, Nozomi Harai, Kyoichiro Tsuchiya   +8 more
wiley   +1 more source

Neoplastic Risk in Patients With Klinefelter Syndrome

Andrology, EarlyView.
ABSTRACT Background Besides gonadal involvement (hypogonadism, male factor infertility, and testicular hypotrophy), patients with Klinefelter syndrome (KS) may suffer from several extra‐gonadic complications, including neoplastic events. Objective The aim of this review is to summarize all major clinical evidence dealing with the association between KS
Andrea Graziani, Giuseppe Grande, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +4 more
wiley   +1 more source

Variants in ZZS Complex‐Associated Genes TEX11 and M1AP Are Responsible for Male Infertility and Nonobstructive Azoospermia

Andrology, EarlyView.
ABSTRACT Background Nonobstructive azoospermia (NOA) is the most severe form of male infertility, with genetic factors contributing to approximately 30% of cases. However, only a small fraction of all NOA cases can be explained by the current genetic findings.
Ao Ma, Hongyi Wang, Shengwei Ke, Ziqi Yu, Xun Wang, Zhiran Li, Yuhang Li, Lv Yao, Fuxing Zhang, Feifei Kong, Lingying Jiang, Xiaozhi Zhao, Beibei Zhang   +12 more
wiley   +1 more source

Prostate morcellation devices: a systematic review and meta‐analysis of clinical outcomes and efficiency

BJU International, EarlyView.
Objective To systematically evaluate the efficiency and safety of different prostate morcellators used during prostate enucleation for benign prostatic hyperplasia (BPH). Methods A systematic review was performed according to the Preferred Reporting Items for Systematic Review and Meta‐analyses guidelines.
Stessy Kutchukian, Pietro Scilipoti, Mikael Abi Abdallah, Astrid La Rosa, Tristan Filler, Frédéric Panthier, Marie Chicaud, Stefano Moretto, Steeve Doizi   +8 more
wiley   +1 more source

The Benign Prostatic Hyperplasia and Its Aetiologies [PDF]

, 2018
This study aimed at investigating the Benign Prostatic Hyperplasia and Its Aetiologies, therefore th prostatic hyperplasia predominantly involves the stromal compartment of the gland and affects more than 70% of men of 70 years or older with or without ...
ALHARBI, MOAZ HASSAN H, ALHARTHI, MOHAMMED ABDULLAH M, NAWAF S, ALOTAIBI SAUD, ALSHAMMARI, MASOUD BASHEER O, ALENZI, AHMAD ENAD J, ALMISTAREHI, ABDEL HAMEED WASFI M, ALHAZMI, ALMOTASEM BLLAH ALI Y   +6 more
core   +1 more source

Health‐related quality of life and patient‐reported outcome measures in economic evaluation of urological technologies: challenges and opportunities

BJU International, EarlyView.
Objective To examine the role of health‐related quality of life (HRQoL) assessments and patient‐reported outcome measures (PROMs) in the economic evaluation of urological interventions, highlighting methodological challenges, and identifying areas for future development.
Mohammed El Bahnasawi, Charlotte Moss, Netty Kinsella, Kathie Alexina Wong, Mieke Van Hemelrijck   +4 more
wiley   +1 more source

Urinary cholesterol in follow-up of patients with urologic carcinomas or benign prostatic hyperplasia [PDF]

, 1981
Tauber, R., Lazik, E., Jüngst, Dieter, Karl, Hans Josef   +3 more
core   +1 more source

Envolvimento da via do óxido nítrico no tratamento e na patogenia da hiperplasia prostática benigna [PDF]

, 2001
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas.As evidências da participação do óxido nítrico (NO) na função prostática nos levaram a estudar o envolvimento deste na Hiperplasia Prostática Benigna (HPB). Na
Cordova, Clarissa Amorim Silva de
core  

Serum sex steroids, gonadotrophins and sex hormone-binding globulin in prostatic hyperplasia

Annals of Saudi Medicine, 2008
Background: Benign prostatic hyperplasia (BPH) develops in elderly males when serum androgens are relatively lower than in healthy younger males, but it is not well understood whether and how sex steroids are altered in prostatic hyperplasia. It is also
Ansari Mohammad Abdul, Begum Dilruba, Islam Fakhrul   +2 more
doaj  

An intracellular recombinant single‐chain variable antibody fragment as a new class of phosphodiesterase type 5 inhibitors

British Journal of Pharmacology, EarlyView.
Background and Purpose Cyclic guanosine monophosphate (cGMP) is a ubiquitous second messenger involved in human (patho‐)physiology. Phosphodiesterase 5 (PDE5) is a major cGMP hydrolyzing enzyme in many cell types including vascular smooth muscle cells (VSMCs). Several highly selective PDE5 inhibitors are in clinical use. However, there are currently no
Kürsat Kirkgöz, Sophie Sprenger, Olga Schweigert, Sanika Mohagaonkar, Matti Walsdorff, Tanja Zeller, Filip Berisha, Viacheslav O. Nikolaev, Sergei D. Rybalkin   +8 more
wiley   +1 more source