Results 11 to 20 of about 77,703 (269)

Hepsin immunohistochemical expression in prostate cancer in relation to Gleason′s grade and serum prostate specific antigen

open access: yesIndian Journal of Pathology and Microbiology, 2011
Background: Hepsin (HPN), a type II trans-membrane serine protease, has been reported to be one of the most up regulated genes in prostate cancer. The aim of the present study was to find out immuno-histochemistry based phenotypic expression of HPN in ...
Madhu Mati Goel   +3 more
doaj   +1 more source

Prostate-Associated Gene 4 (PAGE4): Leveraging the Conformational Dynamics of a Dancing Protein Cloud as a Therapeutic Target. [PDF]

open access: yes, 2018
Prostate cancer (PCa) is a leading cause of mortality and morbidity globally. While genomic alterations have been identified in PCa, in contrast to some other cancers, use of such information to personalize treatment is still in its infancy.
Dorff, Tanya   +6 more
core   +3 more sources

Juvenile prostatic hyperplasia

open access: yesUrology, 2005
Benign prostatic hyperplasia is common in aging men, but rare in childhood. We report a case of juvenile prostatic hyperplasia in a 10-year-old boy, who visited our clinic for hematuria and voiding symptoms. Radiologic studies revealed a huge prostate protruding into the bladder. The prostate was 33 g.
Young Deuk, Choi   +5 more
openaire   +3 more sources

Treatment options in benign prostate hyperplasia associated with lower urinary tract symptoms

open access: yesUrology Research and Practice, 2019
Benign prostatic hyperplasia is a common cause of lower urinary tract symptoms. Men who are treated for benign prostatic hyperplasia potentially reduce their lifetime risk of acute urinary retention and the need for benign prostatic hyperplasia-related ...
Ali Atan, Altuğ Tuncel
doaj   +1 more source

Coupling of alpha(1)-Adrenoceptors to ERK1/2 in the Human Prostate [PDF]

open access: yes, 2011
Introduction: alpha(1)-Adrenoceptors are considered critical for the regulation of prostatic smooth muscle tone. However, previous studies suggested further alpha(1)-adrenoceptor functions besides contraction.
Anglin IE   +39 more
core   +1 more source

A case of giant prostatic hyperplasia

open access: yesAsian Journal of Urology, 2016
Benign prostatic hyperplasia (BPH) is one of the most common conditions experienced by aging males and a frequent cause of bladder outlet obstruction and macroscopic haematuria.
Luke Wang, Paul Davis, Kevin McMillan
doaj   +1 more source

The Influencing Role of Diabetes Mellitus and Hypertension in the Establishment of Benign Prostatic Hyperplasia

open access: yesJournal of Nobel Medical College, 2020
Background: Benign prostatic hyperplasia is regarded as non-malignant growth of prostatic tissueIt is the most common benign tumor in men, and the incidence is age related. In men aged more than 50 years, it is the fourth most prevalent disease.
Ram Sagar Shah, Rabindra Tamang
doaj   +1 more source

The postfinasteride syndrome; an overview [PDF]

open access: yes, 2016
As a 5-α reductase inhibitor, Finasteride has proven effective in ameliorating two conditions documented to be androgen dependent, namely male androgenic alopecia and benign prostatic hyperplasia. Therapeutic results are maintained as long as the drug is
Banu, Petrisor   +9 more
core   +4 more sources

Short-term pretreatment with a dual 5α-reductase inhibitor before bipolar transurethral resection of the prostate (b-turp): evaluation of prostate vascularity and decreased surgical blood loss in large prostates [PDF]

open access: yes, 2015
Objective: To investigate if short-term treatment with dutasteride (8 weeks) before bipolar transurethral resection of the prostate (B-TURP) can reduce intraoperative bleeding, as dutasteride a dual 5α-reductase inhibitor (5-ARI) blocks the conversion of
Amory   +28 more
core   +1 more source

Studies on Chromatographic Fingerprint and Fingerprinting Profile-Efficacy Relationship of Saxifraga stolonifera Meerb.

open access: yesMolecules, 2015
This work investigated the spectrum-effect relationships between high performance liquid chromatography (HPLC) fingerprints and the anti-benign prostatic hyperplasia activities of aqueous extracts from Saxifraga stolonifera.
Xing-Dong Wu   +8 more
doaj   +1 more source

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