Results 31 to 40 of about 150,306 (248)

Role of gangliosides in prostate pathology [PDF]

open access: yesRomanian Journal of Infectious Diseases, 2016
Molecular pathology of benign prostatic hyperplasia is multifactorial and involves endocrine, biochemical, immunological interactions. The mechanisms involved in the onset and progression of benign prostatic hyperplasia are: infections, 50 years of age ...
Ilinca Nicolae   +2 more
doaj   +1 more source

Physiological variables and molecular study of KLK2 and KLK3 among patient with benign prostatic hyperplasia

open access: yesAlexandria Journal of Medicine, 2018
Prostatic hyperplasia is benign tumor occur in prostate. Benign prostatic hyperplasia is common disease in old men. The incidence of disease arises with increase in age.
Mustafa F. Dawood   +2 more
doaj   +1 more source

Silodosin in the treatment of benign prostatic hyperplasia. [PDF]

open access: yes, 2010
Benign prostatic hyperplasia (BPH)-associated lower urinary tract symptoms (LUTS) are highly prevalent in older men. Medical therapy is the first-line treatment for LUTS due to BPH.
Rossi, Maxime   +5 more
core   +1 more source

Canonical Wnt signaling in the regulation of prostate cancer stem cells: a key driver of castration-resistant prostate cancer and a therapeutic opportunity

open access: yesJournal of Translational Medicine
Prostate cancer (PCa) is the second leading cause of cancer-related death among men worldwide. Although androgen deprivation therapy (ADT) effectively suppresses tumor growth, most patients eventually progress to castration-resistant prostate cancer ...
Haoze Li   +7 more
doaj   +1 more source

Optimization of seminal extracellular vesicle isolation protocols for cancer biomarker analysis using proteomic profiling

open access: yesMolecular Oncology, EarlyView.
This paper shows that size‐exclusion chromatography and sequential centrifugation applied to seminal plasma enrich for different populations of extracellular vesicles. This may significantly affect the detection and analysis of extracellular vesicle‐associated cancer biomarkers.
Elen Telumyan   +8 more
wiley   +1 more source

Effect of Educational Guidelines Application on Quality of life among Geriatric Patients having Benign Prostatic Hyperplasia [PDF]

open access: yesEgyptian Journal of Health Care
Background: Benign prostatic hyperplasia is one of the most prevalent disorders in elderly men and non-malignant condition of the prostate, increases morbidity, often resulting in lower urinary tract symptoms, which can have an undesirable influence on a
Laila Awadin Ali Hassan   +5 more
doaj   +1 more source

Comparative application of testosterone undecanoate and/or testosterone propionate in induction of benign prostatic hyperplasia in Wistar rats.

open access: yesPLoS ONE, 2022
Testosterone undecanoate is a hormone agent with long-acting potential and is used for testosterone replacement therapy for hypogonadism. This study was designed to investigate application of testosterone undecanoate in maintaining high androgen levels ...
Jinho An, Hyunseok Kong
doaj   +1 more source

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Prostate Cancer Patient‐Derived Organoids (PDOs) as Functional Avatars for Antisense Oligonucleotide (ASO)‐Based Personalized Therapy

open access: yesAdvanced Healthcare Materials, EarlyView.
Prostate patient‐derived organoids (PDOs) were established from TURP and biopsy specimens with >90% success and retain key features of their tissues of origin, making them functional avatars for antisense oligonucleotide (ASO) therapy . Transfecting single cells outside the Matrigel matrix and then reconstituting organoids overcomes the 3D delivery ...
Thi Thom Tran   +15 more
wiley   +1 more source

Expert consensus on Rezūm™: Indications, surgical technique and postoperative care

open access: yesBJUI Compass
Background Lower urinary tract symptoms associated to benign prostatic hyperplasia (LUTS/BPH) is a growing condition in males associated to a high clinical, economic and humanistic burden.
Emilio López Alcina   +4 more
doaj   +1 more source

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