Results 31 to 40 of about 40,951 (233)

Cholesterol‐Mediated Metabolic‐mechanotransductive Crosstalk Orchestrates Castration Resistance in Prostate Cancer

open access: yesAdvanced Science, EarlyView.
Full androgen deprivation (FAD) induces paracrine cholesterol in prostate cancer that drives the polarization of cancer‐associated fibroblasts (CAFs) and subsequent elevated matrix stiffness. Matrix stiffness in turn potentiates tumor cell survival under FAD pressure via dual mechanotransductive activation of the IRE1α‐XBP1s stress‐response axis ...
Shaojie Liu   +20 more
wiley   +1 more source

The Contribution of Prostatic Acid Phosphatase and Prostatic Specific Antigen in the Diagnosis of Prostatic Cancer

open access: yesThe International Journal of Biological Markers, 1988
Prostatic acid phosphatase (PAP) and prostatic specific antigen (PSA) were measured by immunochemical methods using test preparations from two different companies.
A. van Dalen   +2 more
doaj   +1 more source

Humanized immune system animal models and their recent applications

open access: yesAnimal Models and Experimental Medicine, EarlyView.
In this review, we provide an updated and comprehensive overview of the current state of humanized immune system animal model research. We discuss the variety of techniques used to produce humanized mice with their respective strengths and weaknesses, and evaluate the advantages and limitations of these models, including issues with incomplete immune ...
Nicolas Skuli   +6 more
wiley   +1 more source

Histopathological study of Prostatic Lesions in a Tertiary Care Hospital, Lahore [PDF]

open access: yesJournal of Sharif Medical & Dental College, 2021
Objective: To determine the spectrum of pathological lesions seen in prostatic biopsies & to grade prostatic cancers according to the modified Gleason score & grade.
Madiha Arshad   +2 more
doaj  

Modern competency‐based teaching of human sexual development

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Embryology is an integral part of anatomy and a key subject in basic medical education. The development of the sexual tract, which is closely associated with the formation of the urinary tract and the organs of continence, is particularly complex and relevant for many medical disciplines.
Elisabeth Eppler   +2 more
wiley   +1 more source

THE EFFECT OF FINASTERIDE ON BLEEDING DURING TRANSURETHRAL RESECTION OF THE PROSTATE

open access: yesThe Iraqi Journal of Medical Sciences, 2016
Background: Finasteride is a selective 5-? reductase enzyme inhibitor that blocks the conversion of testosterone to dihydrotestosterone, down regulates prostatic angiogenesis and blood flow and promotes apoptosis of prostatic cells.
Firas S. Al-Qurayshe   +2 more
doaj   +4 more sources

Periodontal disease and risk of benign prostate hyperplasia: a cross-sectional study

open access: yesMilitary Medical Research, 2019
Background Both periodontal disease and benign prostatic hyperplasia are age-related diseases that affect millions of people worldwide. Hence, this study aimed to investigate the association between periodontal disease and the risk of benign prostatic ...
Lan Wu   +8 more
doaj   +1 more source

Benign Prostatic Hyperplasia and Prostate Cancer [PDF]

open access: yesEpidemiologic Reviews, 2001
This paper reviews the epidemiologic studies of benign prostatic hyperplasia in relation to prostate cancer. Such relation was investigated in epidemiologic studies but none have provided clear evidence suggesting an etiologic role for benign prostatic hyperplasia in the development of prostatic cancer.
openaire   +2 more sources

Essential embryology for the Canadian pathologists’ assistant

open access: yesAnatomical Sciences Education, EarlyView.
Abstract Pathologists' assistants (PAs) are pivotal in healthcare, conducting autopsies and examining tissues under a pathologist's guidance. Embryology knowledge is crucial for PAs to accurately assess anomalies and identify pathologies. Yet, it is often overlooked in academic PA training programs.
Samantha H. Nacci   +4 more
wiley   +1 more source

Ocrelizumab‐induced colitis: VigiBase disproportionality analysis, case reports and literature review

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims Ocrelizumab is a humanized anti‐CD20 monoclonal antibody used in multiple sclerosis. Since its commercialization, several cases of ocrelizumab‐induced colitis have been reported in the scientific literature. Methods To explore the potential association of ocrelizumab with colitis as an adverse drug reaction (ADR), we conducted a descriptive and ...
Audrey Fresse   +3 more
wiley   +1 more source

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