Results 71 to 80 of about 56,978 (262)

Frequency and Trends of Prostatic Diseases in a Subset of Karachi Population: A Retrospective Study

Pakistan Journal of Medicine and Dentistry
Background: Prostatic diseases are a leading cause of frequent urinary complaints in elderly males. The most common diseases include prostatitis, benign prostatic hyperplasia, and prostate cancer.
Asma Shabbir, Umaima Tariq Khan, Diya Nasir, Parvesh Kumar Rath, Cheena Kumari, Talat Zehra, Syed Mehmood Hasan   +6 more
doaj   +1 more source

Association of Glucagon‐Like Peptide‐1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes

Obesity, EarlyView.
ABSTRACT Objective The real‐world evidence on the association between glucagon‐like peptide‐1 receptor agonists (GLP‐1RAs) and cancer risk remains limited and mixed. Methods In 2013–2020 national Medicare claims data, we included cancer‐naïve patients with type 2 diabetes (T2D). We identified those who initiated GLP‐1 RA, sodium‐glucose cotransporter 2
Ying Lu, Hao Dai, Huilin Tang, William T. Donahoo, Thomas J. George, Ramon C. Sun, Sizun Jiang, Aik Choon Tan, Yi Guo, Jonathan D. Licht, John M. Allen, Kelvin P. Lee, Jingchuan Guo, Jiang Bian   +13 more
wiley   +1 more source

TRANSCRIPTION FACTOR BRN-3α AND PROSTATE CANCER, RELATION WITH HORMONE RECEPTORS AND AKT/M-TOR SIGNALING PATHWAY ACTIVATION

Сибирский онкологический журнал, 2018
Introduction. The transcription factor Brn-3α (product of the POU4F1) plays a significant role in carcinogenesis. The purpose of the study was to investigate Brn-3α, AR, ERα expressions in tissues of benign prostatic hyperplasia and prostate cancer as ...
L. V. Spirina, A. K. Gorbunov, I. V. Kondakova, E. M. Slonimskaya, E. A. Usynin   +4 more
doaj   +1 more source

PROSTest, a Multigene Liquid Biopsy Signature, Effectively Stratifies Patients With High PSA for Prostate Biopsy

The Prostate, EarlyView.
ABSTRACT Background Prostate‐specific antigen (PSA) remains the standard biomarker for prostate cancer (PCa) detection, but its limited specificity—particularly in the 3–10 ng/mL range—leads to overdiagnosis and unnecessary biopsies. Including multiparameteric MRI (mpMRI) helps to reduce the number of PSA‐false‐positive biopsies, but there is still a ...
Kambiz Rahbar, R. David Rosin, Mark Kidd, Abdel B. Halim, Oliver Sartor   +4 more
wiley   +1 more source

The impact of open benign prostatic hyperplasia surgery on erectile function in patients with benign prostatic hyperplasia, Northeast Ethiopia, 2023.

Medicine Science
Background: It was believed that surgical treatments for benign prostatic hyperplasia could improve erectile function due to the relief of symptoms they were also reported to harm erectile function as heating or injury effect.
Leul Mekonnen Zeru, Mekuriaw Wuhib Shumye, Mitaw Girma Kembaw, Zemen Mengesha Yalew, Getachew Wuhib, Melatwork Assefa, Hailemaryam Shiferaw, Belachew Tegegne Shiferaw   +7 more
doaj   +1 more source

Pathology of a Canine Model of Localized Prostate Carcinoma

The Prostate, EarlyView.
ABSTRACT Background Dogs spontaneously develop prostate carcinoma (PC) and share prostate gland anatomy, physiology, and size to men. Over the last 15 years, we have developed and refined a canine model of focal PC to evaluate therapeutic‐diagnostic (theranostic) interventions.
Nathan K. Hoggard, Felipe M. Berg, Marlon R. Szczepaniak, Xinning Wang, Noriko Kantake, Gopalakrishnan Ramamurthy, Li Gong, Eric T. Hostnik, Krishan Kumar, Arijit Ghosh, Dong Luo, Michael V. Knopp, Jill M. Keller, Evan T. Keller, Agata A. Exner, James P. Basilion, Michael F. Tweedle, Thomas J. Rosol   +17 more
wiley   +1 more source

Unraveling the Metabolic Influence of Olfactory Receptors in Cancer Cells

Sensory Neuroscience, EarlyView.
ORs are aberrantly expressed in various tumor types and regulate cancer cell metabolism through nonclassical signaling pathways, including PI3K/Akt, MAPK, and ERK. These receptors influence tumor proliferation, invasion, and immune evasion. Specific OR–ligand interactions offer promising opportunities for targeted cancer therapy and early diagnosis ...
Chengzhilin Li, Xiaochen Gao, Ziheng Liu, Nianlei Zhang, Xue Cao, Wenwen Qi, Chengcheng Liu   +6 more
wiley   +1 more source

Untargeted metabolomics revealed urinary metabolic pattern for discriminating prostate cancer from benign prostatic hyperplasia in Chinese participants

Frontiers in Oncology
IntroductionPrecise screening and discriminating of prostatic hyperplasia (PH) could avoid unnecessary biopsy and overdiagnosis. However, the metabolic pattern of patients with prostatic hyperplasia in Chinese population is rarely reported.MethodsUrine ...
Chenye Tang, Xiao Guo, Qian Zou, Xinghao Wang, Jian Sheng, Dan Shen, Chun Sun, Shuo Li, Ruilin Shen   +8 more
doaj   +1 more source

Evaluation of the efficacy of post prostatic massage urine cytology in diagnosis of various prostatic lesions with cytohistological and clinical correlation

Journal of Cytology, 2017
Background: Elderly men are at high risk of various prostatic diseases carrying high morbidity and mortality rates. For screening large populations, there is a need for a simple, reliable, and noninvasive test with high sensitivity and specificity ...
Monisha Choudhury, Savita Agarwal
doaj   +1 more source

Diabetes mellitus and prostatic hyperplasia. [PDF]

, 1968
J B Bourke, J. P. Griffin
openalex   +1 more source