Results 91 to 100 of about 802,667 (378)

Editorial comment on: increased expression of tumor-associated trypsin inhibitor, TATI, in prostate cancer and in androgen-independent 22Rv1 cells [PDF]

, 2007
No abstract ...
Edwards, J., Leung, H.Y.
core   +1 more source

The impact of metformin use on the risk of prostate cancer after prostate biopsy in patients with high grade intraepithelial neoplasia

International Brazilian Journal of Urology
Purpose We report our experience on metformin use in diabetic patients and its impact on prostate cancer (PCa) after a high-grade prostatic intraepithelial neoplasia (HGPIN) diagnosis.
Lucio Dell'Atti, Andrea B. Galosi
doaj   +1 more source

Anterior prostate biopsy at initial and repeat evaluation: is it useful to detect significant prostate cancer?

International Brazilian Journal of Urology, 2015
Purpose: Detection rate for anterior prostate cancer (PCa) in men who underwent initial and repeat biopsy has been prospectively evaluated. Materials and Methods: From January 2013 to March 2014, 400 patients all of Caucasian origin (median age 63.5 ...
Pietro Pepe, Michele Pennisi, Filippo Fraggetta   +2 more
doaj   +1 more source

The subcellular distribution of phosphorylated Y‐box‐binding protein‐1 at S102 in colorectal cancer patients, stratified by KRAS mutational status and clinicopathological features

Molecular Oncology, EarlyView.
This study identifies nuclear YB‐1 S102 phosphorylation as a marker associated with KRAS and FBXW7 mutations in colorectal cancer. Mutated KRAS correlates specifically with nuclear, not cytoplasmic, S102 YB‐1. These findings provide the first ex vivo evidence of this link in CRC and suggest future studies should assess the prognostic and therapeutic ...
Konstanze Lettau, Stephan Forchhammer, Birgit Fehrenbacher, Lejla Mahmutovic, Marcus Scharpf, Gunnar Blumenstock, Martin Schaller, Irina Bonzheim, Shayan Khozooei, Mahmoud Toulany   +9 more
wiley   +1 more source

A33 shows similar sensitivity to but is more specific than CDX2 as an immunomarker of colorectal carcinoma [PDF]

, 2017
Aims: CDX2 is widely used as a sensitive and specific immunomarker for colorectal carcinoma (CRC) but neither this sensitivity nor specificity is absolute. This study is the first known comparison of CDX1 and A33 against CDX2 as immunomarkers for CRC.
Adamczyk, Lukasz A., Cullen, Jayne, Evans, Shanna, Oien, Karin A., Oniscu, Anca, Wong, Newton A.C.S.   +5 more
core   +1 more source

Prostatic involvement in disseminated paracoccidioidomycosis: An unusual presentation mimicking malignant neoplasm

Medical Mycology Case Reports, 2020
Paracoccidioidomycosis is a granulomatous fungal infection, endemic to Latin America, which has great economic impact. Prostatic involvement is rare and can simulate other conditions, which poses a diagnostic challenge for the clinician. This article describes the report of a case of disseminated paracoccidioidomycosis with prostatic involvement ...
Camila Mazeiro Gil, Giovanna Locks Silveira, Luiz Jorge Moreira Neto, Nayara de Paula Passarin, Bruna Laginski Passos, Lenir Nogueira Preciliano Marques, Antonio Augusto Claudio Pereira, Simone Bonafé   +7 more
openaire   +4 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Loss of the tumor suppressor, Tp53, enhances the androgen receptor-mediated oncogenic transformation and tumor development in the mouse prostate. [PDF]

, 2019
Recent genome analysis of human prostate cancers demonstrated that both AR gene amplification and TP53 mutation are among the most frequently observed alterations in advanced prostate cancer. However, the biological role of these dual genetic alterations
Aldahl, Joseph, Cardiff, Robert D, Geradts, Joseph, He, Yongfeng, Hooker, Erika, Johnson, Daniel T, Kim, Won Kyung, Le, Vien, Lee, Dong-Hoon, Sun, Zijie, Wu, Huiqing, Yang, Julie S, Yoon, Junhee, You, Sungyong, Yu, Eun-Jeong   +14 more
core  

Prostate cancer incidentally discovered at the time of radical cystoprostatectomy does not decrease overall survival: Results from a large Chinese medical center

International Brazilian Journal of Urology
Purpose To investigate the incidence and pathologic characteristics of prostate cancer (PCa) incidentally discovered at the time of radical cystectomy and its impact on overall survival.
Shiying Tang, Han Hao, Dong Fang, Wei Zheng, Peng Ge, Xiaohong Su, Qun He, Xinyu Yang, Qi Shen, Xuesong Li, Wei Yu, Jian Lin, Liqun Zhou   +12 more
doaj   +1 more source

Paraffin-section detection of CD10 in 505 nonhematopoietic neoplasms. Frequent expression in renal cell carcinoma and endometrial stromal sarcoma.

American Journal of Clinical Pathology, 2000
We tested 505 cases of nonhematopoietic neoplasms by immunohistochemistry using a newly characterized monoclonal antibody (clone 56C6) against the CD10 antigen.
P. Chu, D. Arber
semanticscholar   +1 more source