Results 111 to 120 of about 86,700 (353)

Prognosis of patients with prostate cancer and middle range prostate - specific antigen levels of 20 – 100 ng / mL

International Brazilian Journal of Urology
Introduction: Prostate - specific antigen (PSA) is a useful biomarker for detection of prostate cancer (PCa) and for risk classification in addition to TNM classification and Gleason score (GS). We reported the role of PSA in patients with low (< 20 ng /
Hiroaki Iwamoto, Kouji Izumi, Yoshifumi Kadono, Atsushi Mizokami   +3 more
doaj   +1 more source

The effect of cortisone and cortisol on 17-ketosteroid excretion in carcinoma of the prostate and other neoplasms [PDF]

, 1959
Joseph E. Sokal, K. W. Buchwald
openalex   +1 more source

Genetically supported causality between benign prostate hyperplasia and urinary bladder neoplasms: A mendelian randomization study [PDF]

, 2022
Wenzhi Du, Tianyi Wang, Wenxiu Zhang, Yu Xiao, Xinghuan Wang   +4 more
openalex   +1 more source

ATG4B is required for mTORC1‐mediated anabolic activity and is associated with clinical outcomes in non‐small cell lung cancer

FEBS Open Bio, EarlyView.
The relationship between anabolic and catabolic processes governing lung cancer cell growth is nuanced. We show that ATG4B, an autophagy regulator, is elevated in lung cancer and that high ATG4B is associated with worse patient outcomes. Targeting ATG4B in cells reduces growth, protein synthesis, and mTORC1 activity, demonstrating a new relationship ...
Patrick J. Ryan, Bethany C. Guerra, Selina Uranga, Jessica M. Cardin, Steven E. Riechman, Mariana Janini Gomes, James D. Fluckey   +6 more
wiley   +1 more source

Pathogenic Neurofibromatosis type 1 gene variants in tumors of non‐NF1 patients and role of R1276

FEBS Open Bio, EarlyView.
Somatic variants of the neurofibromatosis type 1 (NF1) gene occur across neoplasms without clinical manifestation of the disease NF1. We identified emerging somatic pathogenic NF1 variants and hotspots, for example, at the arginine finger 1276. Those missense variants provide fundamental information about neurofibromin's role in cancer.
Mareike Selig, Swanhild Lohse, Sara Elahi, Nils Hartmann, Stefanie Deckert, Shutian Si, Alexander Desuki, Anja Harder   +7 more
wiley   +1 more source

Prospective evaluation of Chondroitin sulfate, Heparan sulfate and Hyaluronic acid in prostate cancer

International Brazilian Journal of Urology
Purpose: The present study evaluates chondroitin sulfate (CS) and heparan sulfate (HS) in the urine and hyaluronic acid (HA) in the plasma of patients with prostate cancer before and after treatment compared to a control group.
Matheus N. Ribeiro da Silva, Aline Mendes, João R. Maciel Martins, Marcos Tobias-Machado, Maria Aparecida da Silva Pinhal   +4 more
doaj   +1 more source

Engineering tandem VHHs to target different epitopes to enhance antibody‐dependent cell‐mediated cytotoxicity

FEBS Open Bio, EarlyView.
Tandem VHH targeting distinct EGFR epitopes were engineered into a monovalent bispecific antibody (7D12‐EGA1‐Fc) with more potent ADCC without increasing affinity to EGFR. Structural modeling of 7D12‐EGA1‐Fc showed cross‐linking of separate EGFR domains to enhance CD16a engagement on NK cells.
Yuqiang Xu, Hao Jiang, Limin Chen, Fulai Zhou, Ying Jin, Mark L. Chiu   +5 more
wiley   +1 more source

Representation analysis of miRNA from clarified urine and urine microvesicles in prostate malignancies and non-malignant neoplasms [PDF]

, 2018
Ivan A. Zaporozhchenko, Olga E. Bryzgunova, Evgeniy A. Lekchnov, I.D. Osipov, M. M. Zaripov, Yu. B. Yurchenko, S. V. Yarmoschuk, Oxana A. Pashkovskaya, Elena Y. Rykova, А. А. Жеравин, Pavel P. Laktionov   +10 more
openalex   +1 more source

FGFR Like1 drives esophageal cancer progression via EMT, PI3K/Akt, and notch signalling: insights from clinical data and next‐generation sequencing analysis

FEBS Open Bio, EarlyView.
Clinical analysis reveals significant dysregulation of FGFRL1 in esophageal cancer (EC) patients. RNAi‐coupled next‐generation sequencing (NGS) and in vitro study reveal FGFRL1‐mediated EC progression via EMT, PI3K/Akt, and Notch pathways. Functional assays confirm its role in tumor growth, migration, and invasion.
Aprajita Srivastava, Anoop Saraya, Deepak Gunjan, Rinu Sharma   +3 more
wiley   +1 more source

Clinical and pathologic factors predicting reclassification in active surveillance cohorts

International Brazilian Journal of Urology
The incidence of small, lower risk well-differentiated prostate cancer is increasing and almost half of the patients with this diagnosis are candidates for initial conservative management in an attempt to avoid overtreatment and morbidity associated with
Pablo S. Sierra, Shivashankar Damodaran, David Jarrard   +2 more
doaj   +1 more source