Results 211 to 220 of about 86,700 (353)

Nuclear Factor I‐B Delays Liver Fibrosis by Inhibiting Chemokine Ligand 5 Transcription

Advanced Science, EarlyView.
This study identifies the transcription factor Nuclear Factor I‐B (NFIB) as a key suppressor of liver fibrosis. NFIB expression declines during hepatic stellate cell activation, and its overexpression reduces fibrosis in mice models. The mechanism involves NFIB directly repressing chemokine C─C motif ligand 5 (CCL5), thereby alleviating oxidative ...
Qianqian Chen, Fajuan Rui, Zhiwen Fan, Hongju Yang, Nan Geng, Chenqi Lu, Wenjing Ni, Yue Huan, Junping Shi, Chao Wu, Shengxia Yin, Wei An, Xia Lu, Qianwen Zhao, Jie Li   +14 more
wiley   +1 more source

Evaluating the relationship between educational attainment, obesity-related indicators, and prostate diseases: A univariable and multivariable Mendelian randomization study. [PDF]

Medicine (Baltimore)
Ji WT, Wang YK, Jin XF, Wang SQ, Wang Y.
europepmc   +1 more source

rWTC‐MBTA Vaccine, Alone and Enhanced with Anti‐PD1, Elicits Immune Responses against CNS and Peripheral B‐Cell Lymphoma

Advanced Science, EarlyView.
An autologous whole‐tumor‐cell vaccine (rWTC‐MBTA) is evaluated in murine CNS lymphoma. Subcutaneous vaccination activates dendritic cells, broadens T‐cell priming, and drives lymphocyte trafficking to brain tumors, producing durable tumor control. Longitudinal bioluminescence and adoptive‐transfer assays verify CNS engagement. Combination with anti‐PD‐
Yaping Zhang, Juan Ye, Mitchell Sun, Samik Chakraborty, Alex Valenzuela, Shuran Chen, Qingfeng Xue, Wenyu Shi, Karel Pacak, Herui Wang, Zhengping Zhuang   +10 more
wiley   +1 more source

Robot-assisted laparoscopic prostate-sparing resection of an extremely rare periprostatic solitary fibrous tumor: a case report and literature review. [PDF]

World J Surg Oncol
Xie H, Liang Y, Zhao X, Liu H, Xu Y, Zhang H.   +5 more
europepmc   +1 more source

Expression of ghrelin and biological activity of specific receptors for ghrelin and des-acyl ghrelin in human prostate neoplasms and related cell lines [PDF]

, 2004
Paola Cassoni, Corrado Ghé, Tiziana Marrocco, Elena Tarabra, Elena Allìa, Francesco Catapano, Romano Deghenghi, Ezio Ghigo, Mauro Papotti, Giampiero Muccioli   +9 more
openalex   +1 more source

Parabiosis, Assembloids, Organoids (PAO)

Advanced Science, EarlyView.
This review evaluates parabiosis, organoids, and assembloids as complementary disease models spanning systemic, organ, and multi‐organ levels. It highlights their construction strategies, applications, and current limitations, while emphasizing their integration with frontier technologies such as artificial intelligence, organ‐on‐a‐chip, CRISPR, and ...
Yang Hong, Lavonda Li, Lijie Yan, Long Bai, Jiacan Su, Xingcai Zhang   +5 more
wiley   +1 more source

Diagnostic Algorithm for Secondary Extramammary Paget Disease from Institutional Cases and Literature Review. [PDF]

Cancers (Basel)
Kiratikanon S, Fukui A, Hirata M, Moran JMT, Fujimoto M, Hoang MP.   +5 more
europepmc   +1 more source

ASSESSMENT OF RADIATION REACTIONS IN PATIENTS WITH MALIGNANT NEOPLASM OF THE PROSTATE GLAND ON THE BACKGROUND OF THERMORADITHERAPY

С. А. Фурсов, А. Л. Чернышова, O.A. Tkachuk, Ekaterina Efanova, Olga Anatolyevna Tkachuk, ГБОУ ВО «Новосибирский государственный медицинский университет», Ekaterina Vladimirovna Efanova, ГБОУ ВО «Новосибирский государственный медицинский университет»   +7 more
openalex   +1 more source

Lipid‐Driven OLR1/FOXM1/FGF19 Axis Orchestrates Crosstalk in an Epithelial‐Fibroblast Positive Feedback Promoting Progesterone Resistance in Endometrial Cancer

Advanced Science, EarlyView.
It is revealed that a metabolic–stromal loop driven by oxLDL–OLR1–FOXM1–FGF19 signaling promotes progesterone resistance in endometrial cancer. OxLDL activates epithelial–fibroblast crosstalk, enhancing proliferation and hormonal insensitivity. Disruption of this circuit, especially with resveratrol, restores MPA sensitivity, highlighting a potential ...
Xingchen Li, Yue Qi, Yuman Wu, Xinyi Bi, Yiqin Wang, Jiaqi Wang, Jingyuan Wang, Lingpu Zhang, Haihua Xiao, Jianliu Wang   +9 more
wiley   +1 more source

The utility of radiopharmaceutical uptake in the bladder neck and prostate on preoperative FDG PET/CT in determining urethral surgical margin positivity in patients undergoing radical cystoprostatectomy for bladder cancer. [PDF]

BMC Urol
Aydın R, Ergül RB, Tantekin A, Sanlı Y, Erdem S, Sanlı MO, Ozcan F.   +6 more
europepmc   +1 more source