Results 221 to 230 of about 837,658 (340)

Mechanical Stimuli‐Induced Manipulation of Malignant Behavior in Bioprinted Cancer Microtissues via PI3K/NF‐κB Activation

open access: yesAdvanced Science, EarlyView.
A mechanically tunable ECM platform is created by integrating dECM–alginate matrices with in‐bath tumor printing. The mechanically tunable ECM environment drives tumors to acquire hypoxia, mechanotransduction signaling, metastatic traits, and drug‐resistant phenotypes that collectively promote malignant transformation.
Seok‐Hyeon Lee   +8 more
wiley   +1 more source

EPIDEMIOLOGY OF MALIGNANT PROSTATE NEOPLASMS IN THE SUMY REGION

open access: diamond
Marharita Yasnikova   +3 more
openalex   +2 more sources

Synthesis of Bispecific Conjugates by ADP‐Ribosyl Cyclases

open access: yesAdvanced Science, EarlyView.
Genetic fusion of a CD38 enzymatic domain to antibody scaffolds allows site‐specific conjugation of small‐molecule ligands. Using this approach, a PSMA ligand DUPA is conjugated with an anti‐human CD3 Fab antibody. The resulting bispecific anti‐CD3‐DUPA conjugate facilitates recruitment and activation of cytotoxic T cells against PSMA‐expressing ...
Sunny H. Kim   +8 more
wiley   +1 more source

Polystyrene Microplastics Exposure Aggravates Clear Cell Renal Cell Carcinoma Progression via the NF‐κB and TGF‐β Signaling Pathways

open access: yesAdvanced Science, EarlyView.
This research provides the first comprehensive evidence that PS‐MPs exacerbate ccRCC progression by activating the NF‐κB and TGF‐β pathways. These findings establish PS‐MPs as an environmental risk factor for ccRCC progression and identify the NF‐κB and TGF‐β signaling as potential therapeutic targets to mitigate the adverse effects of ‐PS‐MPs exposure.
Shiqi Ye   +18 more
wiley   +1 more source

Radical prostatectomy for high-risk prostate cancer | Opinion: YES

open access: yesInternational Brazilian Journal of Urology
Leonardo O. Reis   +2 more
doaj   +1 more source

HISTOCHEMICAL STUDIES OF THE DEHYDROGENASE ACTIVITY IN PROSTATIC NEOPLASMS

open access: bronze, 1964
Minoru Kanazawa   +3 more
openalex   +2 more sources

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