Results 221 to 230 of about 802,667 (378)
This study identifies ARID1B as a chromatin‐bound driver of tumor growth in TNBC. ARID1B impairs ARID1A function and directly activates oncogenic programs through SWI/SNF remodeling. Its nuclear localization, mediated by the KPNA2–KPNB1–RANBP2 import machinery, is essential for its tumor‐promoting activity.
Olena Odnokoz+14 more
wiley +1 more source
Prostatic cancer with parotid metastases. [PDF]
Inrhaoun H+10 more
europepmc +1 more source
In tumor cells, ENH prompts the interaction between YAP and KPNA2. This interaction enables YAP to translocate into the nucleus, where it enhances the transcription of CCL5. Consequently, this up‐regulation of CCL5 drives the infiltration of tumor‐associated macrophages (TAMs) and their polarization toward the M2 phenotype, ultimately facilitating ...
Yueli Shi+14 more
wiley +1 more source
Computed Tomographic Analysis of the Anatomical Characteristics of the Canine Prostatic Artery and Development of a Three-Dimensional Canine Prostate Cancer Model for Simulation of Prostatic Artery Embolization. [PDF]
Han J+9 more
europepmc +1 more source
This study revealed that oncogene Collaborator of ARF (CARF) is closely related to B‐cell lymphoma tumorigenesis, and shares a conserved mechanism regulating protein stability with Arabidopsis Kip‐Related Protein6 (KRP6) through casein kinase 1‐mediated phosphorylation. Reduced phosphorylation led to the enhanced protein stability of CARF, resulting in
Li Qu+7 more
wiley +1 more source