Results 31 to 40 of about 86,843 (248)
Nickel and GTP Modulate Helicobacter pylori UreG Structural Flexibility
Biomolecules, 2020 UreG is a P-loop GTP hydrolase involved in the maturation of nickel-containing urease, an essential enzyme found in plants, fungi, bacteria, and archaea.
Annalisa Pierro +7 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Arteriovenous malformations (AVMs) are rare, high‐flow, vascular anomalies that can occur either sporadically or as part of a genetic syndrome. AVMs can progress with serious morbidity and even mortality if left unchecked. Sirolimus is an mTOR inhibitor that is effective in low‐flow vascular malformations; however, its role in AVMs is unclear.
Will Swansson +3 more
wiley +1 more source
Intravitreal GD2‐Specific Chimeric Antigen Receptor T‐Cell Therapy for Refractory Retinoblastoma
Pediatric Blood &Cancer, EarlyView.ABSTRACT Effective treatments for advanced, treatment‐resistant retinoblastoma (RB) remain limited. GD2‐specific chimeric antigen receptor (CAR) T cells show potent antitumor activity with minimal toxicity but have not previously been evaluated in RB.
Subongkoch Subhadhirasakul +13 more
wiley +1 more source
Fabrication et caractérisation physico-chimique d'un fromage "blanc" fabriqué à partir de lait de chamelle - Une comparaison avec le lait de vache [PDF]
, 2014 Habituellement, le lait de chamelle est consommé cru ou pasteurisé. Une autre possible valorisation du lait de chamelle est de le transformer en fromage.
Beaucher, Eric +5 more
core
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Kaposiform lymphangiomatosis (KLA) is an aggressive complex lymphatic anomaly. Patients exhibit malformed lymphatic vessels and often develop hemorrhagic effusions and elevated angiopoietin‐2 (Ang‐2) levels. A somatic NRAS p.Q61R (NRASQ61R) mutation has been associated with KLA.
C. Griffin McDaniel +3 more
wiley +1 more source
La nutrition azotée influence l’ingestion chez la vache laitière
INRAE Productions Animales, 2003 L’augmentation des teneurs en protéines des régimes est souvent associée à une augmentation de l’ingestion chez les vaches laitières, mais l’amplitude de ces réponses et les mécanismes sont encore mal connus.
P. FAVERDIN +3 more
doaj +1 more source
Germline TP53 Mutations Causing Diamond–Blackfan Anemia: A French Report
Pediatric Blood &Cancer, EarlyView.ABSTRACT Diamond–Blackfan anemia is a rare congenital erythroblastopenia typically caused by mutations in ribosomal protein genes. Recently, gain‐of‐function mutations in TP53 have been identified as a novel cause of Diamond–Blackfan anemia. We report two French patients who both harbored a heterozygous TP53 deletion (NM_000546.5: c.1077delA; p ...
Rafael Moisan +6 more
wiley +1 more source
INRAE Productions Animales, 2000 La digestion intestinale des protéines alimentaires fait intervenir des protéases d’origine pancréatique et des peptidases intestinales. Les produits de la digestion sont constitués d’acides aminés libres et de peptides relativement abondants.
N. LE FLOC’H, B. SEVE
doaj +1 more source
Protein context shapes the specificity of SH3 domain-mediated interactions in vivo
Nature Communications, 2021 The SRC Homology 3 (SH3) domains mediate protein–protein interactions (PPIs). Here, the authors assess the SH3-mediated PPIs in yeast, and show that the identity of the protein itself and the position of the SH3 both affect the interaction specificity ...
Ugo Dionne +14 more
doaj +1 more source
Development of ex vivo organ culture models to mimic human corneal scarring [PDF]
, 2012 PURPOSE: To develop ex vivo organ culture models of human corneal scarring suitable for pharmacological testing and the study of the molecular mechanisms leading to corneal haze after laser surgery or wounding.
Damour, O +6 more
core +1 more source