Results 161 to 170 of about 11,335 (243)

Control of airway basal stem cell-mediated lung repair by TGF-β signaling. [PDF]

Sci Adv
Zou T, Zhang S, Liu M, Chen Q, Wang S, Niu L, Chen YG, Zhang T, Zuo W.   +8 more
europepmc   +1 more source

Therapeutic horizons in the development of PROTAC-based EZH2 inhibitors: recent achievements, comparative analysis, and future perspectives. [PDF]

RSC Adv
S Abulkhair H.
europepmc   +1 more source

Therapeutic advances in acute myeloid leukemia: from LSD1 blockade to PROTAC-based strategies. [PDF]

Ann Med Surg (Lond)
Khan SA, Qamar MA, Feroze MT.
europepmc   +1 more source

Unhooking the Hook: Optimization of the Aurora A Targeting PROTAC <b>JB170</b> to <b>CCT400028</b>, an <i>In Vitro</i> Degrader Chemical Probe. [PDF]

J Med Chem
O'Hanlon JA, Gutsche K, Müller JE, Ranjan Prusty N, Mirza A, Roumeliotis TI, Yang H, Stubbs M, Hallett ST, Eing L, McAndrew PC, Choudhary JS, Le Bihan YV, Caldwell J, van Montfort RLM, Workman P, Wolf E, Newton GK, Evans LE.   +18 more
europepmc   +1 more source

Allosteric PROTACs: Expanding the Horizon of Targeted Protein Degradation. [PDF]

J Am Chem Soc
Frost A, O'Connor S, Ciulli A.
europepmc   +1 more source

Targeting the ubiquitin-proteasome system and drug therapy in colorectal cancer. [PDF]

J Mol Cell Biol
Su R, Shao Y, Wang Q, Liu D, Wang Y, Kong D, Qiu Y.   +6 more
europepmc   +1 more source

Rubimaillin ameliorates liver fibrosis by triggering the ferroptosis of activated hepatic stellate cells through targeting CPT1A. [PDF]

Int J Biol Sci
Zhang D, Tang Q, He X, Wen C, Zhou F, Wei X, Wang Z, Wang J, Liu W, Xu Y, Jiang Y, Yin H.   +11 more
europepmc   +1 more source

Evolution of proteolysis-targeting chimeras (PROTAC) technology to overcome challenges of antimicrobial resistance. [PDF]

NPJ Antimicrob Resist
Sarwan DN, Khedekar PB, Bhole RP, Chikhale RV.   +3 more
europepmc   +1 more source

A Gold-PROTAC Degrades the Oncogenic Tyrosine Kinase MERTK: Insights into the Degradome from a Steady-State System. [PDF]

ACS Chem Biol
Thomas SR, Iellici T, Park M, Klaus E, Bileck A, Gerner C, Meier-Menches SM, Casini A.   +7 more
europepmc   +1 more source