Results 181 to 190 of about 11,341 (256)

PROTAC-Mediated Ternary Complex Stability with Ricin Toxin A: A Computational Perspective. [PDF]

ACS Omega
Botelho FD, Islam ST, LaPlante SR, Franca TCC.   +3 more
europepmc   +1 more source

Protacs in oral cancer: degrading oncogenic drivers for next-generation therapy. [PDF]

Front Oral Health
Prasad P, Al Maslamani MJ, Dinislam K, Tasqeruddin S, Shamsi A.   +4 more
europepmc   +1 more source

Targeted Degradation of Histone Deacetylase 8 Using Proteolysis Targeting Chimeras Technology: A Promising Approach for Glioblastoma Treatment. [PDF]

Drug Des Devel Ther
Chotitumnavee J, Seemaung P, Settacomkul R, Sukprasert R, Itoh Y, Suzuki T, Srihirun S, Power C, Vivithanaporn P.   +8 more
europepmc   +1 more source

Investigations into linker effects of DNA-VHL ligand conjugates by multiplexed affinity measurements using focal molography. [PDF]

RSC Chem Biol
Raschke P, Notova S, Gatterdam V, Frutiger A, Brunschweiger A.   +4 more
europepmc   +1 more source

Peptide-Based PROTACs: Transitioning from Static Paradigm to a Dynamic Landscape within Targeted Protein Degradation. [PDF]

Bioconjug Chem
Lu X, Hu Q.
europepmc   +1 more source

PROTAC approaches against drug-resistant EGFR^{C797S/L858R/T790M} mutants: biological evaluation and SAR studies (2020-2025). [PDF]

RSC Med Chem
Kumar A, Sharma V, Kumari P, Kaur R, Bhatia R.   +4 more
europepmc   +1 more source

Editorial: Next-generation PROTACs in oncology and beyond: exploring therapeutic targets and their degraders. [PDF]

Front Pharmacol
Liao D, Bandyopadhyay D.
europepmc   +1 more source

EZH2 PROTACs outperform catalytic inhibitors in prostate cancer by targeting a methylation-independent function of PRC2. [PDF]

Oncogene
Xie W, Chu Q, Brea L, Zeng G, Wang Y, Lu X, Zheng M, Ley CR, Lei Z, Shi H, Zhu JL, Gong L, Martin MC, Shi X, Gritsina G, Grigorescu AA, Chandonnet H, Liu X, Zhao JC, Schiltz GE, Yu J.   +20 more
europepmc   +1 more source

Unlocking the therapeutic potential of HDAC8-degrading PROTACs: progress, challenges, and future directions. [PDF]

RSC Med Chem
Banerjee S, Adhikari N, Ghosh B.
europepmc   +1 more source

Nano-PROTACs for precision medicine: engineering strategies for enhanced targeting and potency. [PDF]

J Nanobiotechnology
Yang X, Wang D, Li C, Zhang Y, Yang J, Liu M, Xing D, Jiang W, Xu S, Wang C.   +9 more
europepmc   +1 more source