Results 171 to 180 of about 8,212 (230)

A General Photoredox Platform for the Hydroarylation of Olefins. [PDF]

J Am Chem Soc
Li YL, Wang JZ, MacMillan DWC.
europepmc   +1 more source

Proteolysis‑targeting chimeras in oral squamous cell carcinoma: Current evidence, translational challenges and future directions (Review). [PDF]

Mol Med Rep
Bai Y, Ma D, Yang X, Wang M.
europepmc   +1 more source

Structural diversity and chemical space analysis of a PROTAC database using unsupervised machine learning. [PDF]

Sci Rep
Kharwar A, Marbán-González A, Medina-Franco JL, Velázquez-Martínez CA.   +3 more
europepmc   +1 more source

An antibody-PROTAC conjugate targets BRD4/c-Myc/PD-L1 to enhance immunotherapy efficacy in triple-negative breast cancer. [PDF]

Cell Rep Med
Gu Y, Li C, Zhao Y, Xu T, Zhu Y, Wang D, Wang X, Chen J, Li J, Guan X.   +9 more
europepmc   +1 more source

From prediction to performance: <i>In silico</i>-supported formulation of amorphous solid dispersions for PROTAC NX-2127. [PDF]

Int J Pharm X
Stakemeier A, Mild L, Sievers J, Kalasová J, Steffens KE, Kuentz M, Steinebach C, Wagner KG.   +7 more
europepmc   +1 more source

Dual PROTACs Versus Dual Inhibitors in Oncology: A Medicinal Chemistry and Linker Design Perspective. [PDF]

Pharmaceuticals (Basel)
Bisi N, Hamze A.
europepmc   +1 more source

COMPASS: A Computational Pipeline to Identify Linkers Predicting Ubiquitinable PROTAC-Induced Ternary Complexes. [PDF]

ChemMedChem
Sueron S, Mahdizadeh SJ, Chevet E, Guillory X, Porée FH, Eriksson LA.   +5 more
europepmc   +1 more source

Clinical Breakthrough in Targeted Protein Degradation: Reflections on the Approval of ARV‐471

Cancer Innovation
Yu Rao
doaj   +1 more source

Multicomponent Stapling of Glucagon-Like Peptide-1 Enables Receptor-Guided PROTAC Delivery. [PDF]

Angew Chem Int Ed Engl
Venne JL, Krajcovicova S, Davies G, Bolt H, Revell J, Spring DR.   +5 more
europepmc   +1 more source