Results 191 to 200 of about 14,786 (290)

Degradación proteica inducida: Un paradigma emergente de descubrimiento de fármacos [PDF]

, 2017
Michalska Dziama, Patrycja
core   +1 more source

A machine learning-based pharmacokinetics predictor (EGFR-PROPK) for EGFR-targeting PROTACs. [PDF]

Commun Chem
Zhang R, Li F, Liu Y, Geng Y, Zhou Y, Zeng L, Bai F.   +6 more
europepmc   +1 more source

Peptide-Based PROTACs: Transitioning from Static Paradigm to a Dynamic Landscape within Targeted Protein Degradation. [PDF]

Bioconjug Chem
Lu X, Hu Q.
europepmc   +1 more source

PROTAC-Mediated Targeted Degradation of MDM2 Induces Tumor-Suppressive Signaling in Osteosarcoma Cells. [PDF]

Cells
Kim Y, Kim JW, Choi J, Kim J, Park S, Choi W, An H, Kim J, Kim M, Choi S, Lim J, Lee HI, Lee S.   +12 more
europepmc   +1 more source

PROTAC-mediated multi-target protein degradation in Alzheimer's disease: mechanistic insights, therapeutic applications, and translational challenges. [PDF]

RSC Med Chem
Wang B, Li Y, Yao T, Shen X, Li H, Jiang W, Li X, Zhu Z.   +7 more
europepmc   +1 more source

Editorial: Next-generation PROTACs in oncology and beyond: exploring therapeutic targets and their degraders. [PDF]

Front Pharmacol
Liao D, Bandyopadhyay D.
europepmc   +1 more source

Integrated computational screen and validation of thalidomide-based PROTACs targeting SARS-CoV-2 main protease. [PDF]

RSC Med Chem
Guo LN, Li YH, Zhu RY, Su N, Shao ZY, Diao H.   +5 more
europepmc   +1 more source

The Multifaceted Legacy of Thalidomide: Chemistry and Biology Driving Modern Drug Design. [PDF]

ChemMedChem
Nikovia K, Kapsalis M, Georgoulakis M, Panousis A, Neochoritis CG.   +4 more
europepmc   +1 more source

ICBS & ECBS Chemical Biology Meeting 2015 - Let them come to Berlin! [PDF]

, 2016
Komatsu, Toru, Virdee, Satpal
core   +2 more sources

Allosteric PROTACs: Expanding the Horizon of Targeted Protein Degradation. [PDF]

J Am Chem Soc
Frost A, O'Connor S, Ciulli A.
europepmc   +1 more source