Results 1 to 10 of about 17,400 (188)

Rare surfactant‐related variants in familial and sporadic pulmonary fibrosis

open access: yesHuman Mutation, Volume 43, Issue 12, Page 2091-2101, December 2022., 2022
Abstract The role of constitutional genetic defects in idiopathic pulmonary fibrosis (IPF) is increasingly appreciated. Monogenic disorders associated with IPF affect two pathways: telomere maintenance, accounting for approximately 10% of all patients with IPF, and surfactant biology, responsible for 1%–3% of cases and often co‐occurring with lung ...
Rachel M. Sutton   +10 more
wiley   +1 more source

Panorama of the Intracellular Molecular Concert Orchestrated by Actinoporins, Pore-Forming Toxins from Sea Anemones

open access: yesToxins, 2021
Actinoporins (APs) are soluble pore-forming proteins secreted by sea anemones that experience conformational changes originating in pores in the membranes that can lead to cell death. The processes involved in the binding and pore-formation of members of
Carlos Alvarez   +8 more
doaj   +1 more source

Successful cardiopulmonary cerebral resuscitation incorporating defibrillation in a filly with neonatal maladjustment syndrome following a routine anaesthetic procedure

open access: yesEquine Veterinary Education, Volume 35, Issue 2, Page e77-e85, February 2023., 2023
Summary A 10‐h‐old 56‐kg Thoroughbred filly was presented for treatment of partial failure of passive transfer of immunity and presumed neonatal maladjustment syndrome (NMS). The filly was hospitalised, and supportive care initiated. On Day 5 of hospitalisation, seizures were observed and were controlled with IV administration of diazepam.
Sarah A. Wiechert‐Brown   +4 more
wiley   +1 more source

Isolation and Characterization of NpCI, a New Metallocarboxypeptidase Inhibitor from the Marine Snail Nerita peloronta with Anti-Plasmodium falciparum Activity

open access: yesMarine Drugs, 2023
Metallocarboxypeptidases are zinc-dependent peptide-hydrolysing enzymes involved in several important physiological and pathological processes. They have been a target of growing interest in the search for natural or synthetic compound binders with ...
Aymara Cabrera-Muñoz   +7 more
doaj   +1 more source

Detection and Characterization of Paraproteinemia in Canine Chronic B‐cell Lymphocytic Leukemia Using Routine and Free Light Chain Immunofixation

open access: yesVeterinary Clinical Pathology, Volume 51, Issue 4, Page 551-559, December 2022., 2022
Abstract Background Hyperglobulinemia is reported in 26% of canine chronic B‐cell lymphocytic leukemia (B‐CLL) cases. However, few cases have been characterized by protein electrophoresis and immunofixation (IF), and the incidence of a monoclonal protein (M‐protein) is unknown using these techniques.
R. Adam Harris   +4 more
wiley   +1 more source

Genome-Wide Analysis of the COBRA-Like Gene Family Supports Gene Expansion through Whole-Genome Duplication in Soybean (Glycine max)

open access: yesPlants, 2021
The COBRA-like (COBL) gene family has been associated with the regulation of cell wall expansion and cellulose deposition. COBL mutants result in reduced levels and disorganized deposition of cellulose causing defects in the cell wall and inhibiting ...
Sara Sangi   +6 more
doaj   +1 more source

Introduction to the study of the changes in sunflower seeds during their storage

open access: yesGrasas y Aceites, 1995
A comparative study has been performed to examine the alterations occurring in sunflower seeds during their storage in an air atmosphere and in a nitrogen current.
I. Otero Mateos   +3 more
doaj   +1 more source

Computer-aided design of bromelain and papain covalent immobilization

open access: yesRevista Colombiana de Biotecnología, 2014
Enzymes as immobilized derivatives have been widely used in Food, Agrochemical, Pharmaceutical and Biotechnological industries. Protein immobilization is probably the most used technology to improve the operational stability of these molecules. Bromelain
Bessy Cutiño-Avila   +9 more
doaj   +1 more source

Integration of genome-wide association studies and gene coexpression networks unveils promising soybean resistance genes against five common fungal pathogens

open access: yesScientific Reports, 2021
Soybean is one of the most important legume crops worldwide. However, soybean yield is dramatically affected by fungal diseases, leading to economic losses of billions of dollars yearly.
Fabricio Almeida-Silva   +1 more
doaj   +1 more source

Partial purification of peptides present in the Tityus macrochirus (Buthidae) scorpion venom and preliminary assessment of their cytotoxicity

open access: yesBiomédica: revista del Instituto Nacional de Salud, 2017
Introduction: Scorpion venom contains peptides with neurotoxic action primarily active on ion channels in the nervous system of insects and mammals. They are also characterized as cytolytic and anticancer, biological characteristics that have not yet ...
Clara Andrea Rincón-Cortés   +2 more
doaj   +1 more source

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