Results 11 to 20 of about 130,827 (178)

An information-theoretic argument for the restriction of the current biological alphabets to 4 nucleotides and 20 amino acids [PDF]

Scientific Reports
Life as we know it is based on foldable biopolymers encoded with just 4 nucleotides or 20 amino acids. Evolution of these biopolymers requires effective and fast search of both the conformational space for folding and the sequence space for evolution ...
Ezequiel Alejandro Galpern, Diego Ulises Ferreiro, Ignacio Enrique Sánchez   +2 more
doaj   +2 more sources

Regulación de receptores de neurotransmisores y neuromoduladores por proteínas estructurales [PDF]

, 2003
[cat] Los receptores acoplados a proteína G o de siete dominios transmembrana (GPCRs o 7TMR) constituyen la mayor superfamilia de receptores de membrana involucrados en la transducción de una señal extracelular al interior de la célula.
Burgueño Hurtado, Javier
core   +6 more sources

Panorama of the Intracellular Molecular Concert Orchestrated by Actinoporins, Pore-Forming Toxins from Sea Anemones

Toxins, 2021
Actinoporins (APs) are soluble pore-forming proteins secreted by sea anemones that experience conformational changes originating in pores in the membranes that can lead to cell death. The processes involved in the binding and pore-formation of members of
Carlos Alvarez, Carmen Soto, Sheila Cabezas, Javier Alvarado-Mesén, Rady Laborde, Fabiola Pazos, Uris Ros, Ana María Hernández, María Eliana Lanio   +8 more
doaj   +1 more source

Arginine substitution by alanine at the P1 position increases the selectivity of CmPI-II, a non-classical Kazal inhibitor

Biochemistry and Biophysics Reports, 2021
CmPI-II is a Kazal-type tight-binding inhibitor isolated from the Caribbean snail Cenchritis muricatus. This inhibitor has an unusual specificity in the Kazal family, as it can inhibit subtilisin A (SUBTA), elastases and trypsin. An alanine in CmPI-II P1
Laritza Rojas, Aymara Cabrera-Muñoz, Dayrom Gil Pradas, Jessica B. González, Maday Alonso-del-Rivero, Yamile González-González   +5 more
doaj   +1 more source

Isolation and Characterization of NpCI, a New Metallocarboxypeptidase Inhibitor from the Marine Snail Nerita peloronta with Anti-Plasmodium falciparum Activity

Marine Drugs, 2023
Metallocarboxypeptidases are zinc-dependent peptide-hydrolysing enzymes involved in several important physiological and pathological processes. They have been a target of growing interest in the search for natural or synthetic compound binders with ...
Aymara Cabrera-Muñoz, Yusvel Sierra-Gómez, Giovanni Covaleda-Cortés, Mey L. Reytor, Yamile González-González, José M. Bautista, Francesc Xavier Avilés, Maday Alonso-del-Rivero   +7 more
doaj   +1 more source

17-epi-Melianodiol, a new protolimonoid from Melia azedarach fruits, exhibits larvicidal activity and is associated with oxidative imbalance and midgut epithelial damage in Aedes aegypti larvae. [PDF]

Pest Manag Sci
The bio‐guided phytochemical study resulted in the new compound 17‐epi‐melianodiol. The compound eliminated 100% of Aedes aegypti larvae at 100 ppm, causing pronounced morphological changes, cuticular damage, and extensive vacuolization. Abstract BACKGROUND In Brazil, Aedes aegypti is the primary vector of arboviruses such as dengue, chikungunya ...
Soares KDC, Nogueira TSR, Bertonceli MAA, da Silva Robaina RR, da Rocha LO, Lemos FJA, Fernandes KVS, Braz-Filho R, Curcino Vieira IJ.   +8 more
europepmc   +2 more sources

Introduction to the study of the changes in sunflower seeds during their storage

Grasas y Aceites, 1995
A comparative study has been performed to examine the alterations occurring in sunflower seeds during their storage in an air atmosphere and in a nitrogen current.
I. Otero Mateos, J. L. Casimiro-Soriguer Escofet, F. Romero Guzmán, J. Pereda Marín   +3 more
doaj   +1 more source

IGA MULTIPLE MYELOMA ASSESMENT WITH HEVYLITE ASSAY

Hematology, Transfusion and Cell Therapy, 2023
Introduction: A key element on Multiple Myeloma (MM) evaluation is the quantification of monoclonal proteins. Current techniques include Serum Protein Electrophoresis (SPE), Immunofixation (IFE) and Free Light Chain Assay (FLC, Freelite).
G Virginia, C Silvina, F Delgado, EM Soares   +3 more
doaj   +1 more source

Genome-Wide Analysis of the COBRA-Like Gene Family Supports Gene Expansion through Whole-Genome Duplication in Soybean (Glycine max)

Plants, 2021
The COBRA-like (COBL) gene family has been associated with the regulation of cell wall expansion and cellulose deposition. COBL mutants result in reduced levels and disorganized deposition of cellulose causing defects in the cell wall and inhibiting ...
Sara Sangi, Paula M. Araújo, Fernanda S. Coelho, Rajesh K. Gazara, Fabrício Almeida-Silva, Thiago M. Venancio, Clicia Grativol   +6 more
doaj   +1 more source

Computer-aided design of bromelain and papain covalent immobilization

Revista Colombiana de Biotecnología, 2014
Enzymes as immobilized derivatives have been widely used in Food, Agrochemical, Pharmaceutical and Biotechnological industries. Protein immobilization is probably the most used technology to improve the operational stability of these molecules. Bromelain
Bessy Cutiño-Avila, Dayrom Gil Pradas, Carlos Aragón Abreu, Yuniel Fernández Marrero, Martha Hernández de la Torre, Emir Salas Sarduy, María de los Ángeles Chávez Planes, José Manuel Guisán Seijas, Joaquín Díaz Brito, Alberto del Monte-Martínez   +9 more
doaj   +1 more source