Results 51 to 60 of about 8,592 (243)

Relació estructura-funció de les proteïnes implicades en la leucoencefalopatia megalencefàlica amb quists subcorticals [PDF]

open access: yes, 2021
Programa de Doctorat en BiomedicinaLa Leucoencefalopatia Megalencefàlica amb Quists subcorticals (de l’anglès Megalencephalic Leukoencephalopathy with subcortical Cysts, MLC) és un tipus rar de leucodistròfia caracteritzada per la presència de vacuoles ...
Xicoy Espaulella, Efren
core  

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

open access: yesFEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho   +3 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

open access: yesFEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes   +3 more
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

open access: yesFEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe   +3 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Apports et utilisation de la prospective « Protéines »

open access: yesOléagineux, Corps gras, Lipides, 2002
Les multiples facettes du « système protéines » et la nécessité de les considérer simultanément pour réfléchir à l’avenir : Quel doit être l’objet d’une prospective sur les protéines à l’Inra ? Quel est le système étudié ? Cette question est fondamentale
Sebillotte Michel
doaj   +1 more source

Influence d’une supplémentation de la ration en lipides sur la qualité du lait chez la vache

open access: yesINRAE Productions Animales, 1992
L’enrichissement en matières grasses des rations est couramment pratiqué pour les vaches laitières fortes productrices. L’une des conséquences les plus fréquentes est la diminution de la teneur en protéines, et plus particulièrement en caséines du lait ...
M. DOREAU, Y. CHILLIARD
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Microalgae as a potential source of single-cell proteins. A review

open access: yesBiotechnologie, Agronomie, Société et Environnement, 2016
Introduction. Les microalgues peuvent être considérées comme une des sources fiables de nutriments et d'autres substances de valeur pouvant satisfaire le besoin croissant en aliment et en énergie.
Barka, A., Blecker, C.
doaj  

Les matières premières agricoles pour l’alimentation humaine et animale : le monde

open access: yesINRAE Productions Animales, 2019
Les produits agricoles cultivés et utilisés dans le monde servent traditionnellement à nourrir les Hommes et les animaux et aussi à certains usages non-alimentaires.
Yves DRONNE
doaj   +1 more source

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