Results 11 to 20 of about 8,586 (162)

Characterization of N-Terminal Acetylated α-Hemoglobin Stabilizing Protein (AHSP) by Top-Down High-Resolution Mass Spectrometry From Human Preterm Newborns Oral Fluid. [PDF]

Rapid Commun Mass Spectrom
ABSTRACT Rationale Alpha‐hemoglobin stabilizing protein (AHSP) is an erythroid‐specific protein forming a stable complex with free α‐hemoglobin, but not with β‐hemoglobin or hemoglobin A (α2β2), thus preventing harmful aggregation of α‐hemoglobin during normal erythroid cell development and avoiding its pro‐oxidant activity.
Iavarone F, Tirone C, Fattore S, De Tomaso D, Menzella N, Vento G, Olianas A, Manconi B, Cabras T, Guadalupi G, Contini C, Boroumand M, Desiderio C, Muntiu A, Fiorita A, Fraschini M, Fanos V, Faa G, Messana I, Castagnola M.   +19 more
europepmc   +2 more sources

HLA-B Serine 116 Confers Protection Against Severe COVID-19 in a Cohort From Rio de Janeiro, Brazil. [PDF]

HLA
ABSTRACT COVID‐19 is a respiratory disease caused by SARS‐CoV‐2, in which severe outcomes are primarily driven by an exacerbated immune response. The HLA region has been extensively investigated in COVID‐19 due to its central role in the immune response, although genetic associations vary across populations.
Pereira MADS, Ferreira SN, Gonçalves CCA, Reis MCD, Zampier CDP, Leitão IC, Lopes MSA, Rossi AD, Soares-Lima SC, Galliez RM, Barroso SPC, Junior ODCF, Tanuri A, Castiñeiras TMPP, Rossi ÁD, Cardoso CC.   +15 more
europepmc   +2 more sources

ETV5 regulates proliferation and cell cycle genes in the INS‐1 (832/13) cell line independently of the concentration of secreted insulin

FEBS Open Bio, Volume 13, Issue 12, Page 2263-2272, December 2023., 2023
The transcription factor ETV5 promotes cell proliferation in the INS‐1 (832/13) cell line by regulating gene expression of E2F1, cyclin/CDK inhibitors (p21Cdkn1a, p27Cdkn1b, and p57Cdkn1c), and cell cycle activators (PAK3 and FOS). This effect is independent of the concentration of secreted insulin. The transcription factor E‐twenty‐six variant 5 (ETV5)
Yael E. Díaz‐López, Gloria Erandi Pérez‐Figueroa, Vicenta Cázares‐Domínguez, María E. Frigolet, Ruth Gutiérrez‐Aguilar   +4 more
wiley   +1 more source

Nanohaloarchaea as beneficiaries of xylan degradation by haloarchaea

Microbial Biotechnology, Volume 16, Issue 9, Page 1803-1822, September 2023., 2023
Using samples of natural evaporitic brines and anthropogenic solar salterns, we describe genome‐inferred trophic relations in two extremely halophilic xylan‐degrading three‐member consortia. We succeeded in genome assembly and closure for all members of both xylan‐degrading cultures and elucidated the respective food chains within these consortia.
Violetta La Cono, Enzo Messina, Oleg Reva, Francesco Smedile, Gina La Spada, Francesca Crisafi, Laura Marturano, Noa Miguez, Manuel Ferrer, Elena A. Selivanova, Olga V. Golyshina, Peter N. Golyshin, Manfred Rohde, Mart Krupovic, Alexander Y. Merkel, Dimitry Y. Sorokin, John E. Hallsworth, Michail M. Yakimov   +17 more
wiley   +1 more source

Myosin 1g as a high-risk biomarker in a pediatric patient with lineage switch from acute lymphoblastic leukemia to myeloid phenotype

Boletín Médico del Hospital Infantil de México, 2023
Background: Myosin 1g (Myo1g) has recently been identified as a potential diagnostic biomarker in childhood acute lymphocytic leukemia (ALL). Case report: We describe the case of a 1-year-old Mexican female patient.
Janeth E. Araujo-Cárdenas, Miguel A. Rodríguez-Ruiz, Jaime A. López-Valdez, Rosa I. Rodríguez-Téllez, Yanelly Garfias-Gómez, Israel Parra-Ortega, Genaro Patiño-López   +6 more
doaj   +1 more source

Phasins PhbP2 and PhbP3 Are Involved in the Depolymerization of Polyhydroxybutyrate in Azotobacter vinelandii

Journal of Basic Microbiology, Volume 65, Issue 12, December 2025.
ABSTRACT Polyhydroxybutyrate (PHB) is a natural polyester synthesized and stored intracellularly as cytoplasmic granules, serving as a carbon and energy reserve in certain bacteria. These granules are surrounded by a variety of proteins, including those directly involved in PHB metabolism—both in its synthesis and degradation—as well as a group of non ...
Jessica Ruiz‐Escobedo, Josefina Guzmán, Guadalupe Espín, Thalía Barrientos‐Millán, Andrea Moyao‐Mejía, Carlos Peña, Soledad Moreno, Erika P. Meneses‐Romero, Daniel Segura   +8 more
wiley   +1 more source

La aplicación de las ciencias bioforenses a la investigación del bioterrorismo y biocrimen

Ciencia Policial
En los últimos años las técnicas de biología molecular han experimentado un avance enorme en todos sus campos. Esto hace que las capacidades de análisis cualitativo, cuantitativo y de tiempos de procesamiento hayan mejorado mucho, en especial con la ...
Desiderio José Ordoño Ballesteros
doaj   +1 more source

Proteómica y biología de sistemas para el estudio de la alergia alimentaria

Arbor: Ciencia, Pensamiento y Cultura, 2020
La alergia alimentaria es el cuarto principal proble­ma de salud pública según datos de la Organización Mundial de la Salud (OMS). Afecta a un total de 6-8% de niños y a 2-4% de adultos.
Mónica Carrera
doaj   +1 more source

Proteoma urinario en la enfermedad renal diabética. Estado del arte

Revista Colombiana de Nefrología, 2021
La enfermedad renal diabética (ERD) es la principal complicación microvascular de los pacientes con diabetes mellitus; esta es una entidad que genera un aumento significativo en la mortalidad de origen cardiovascular de este grupo de pacientes, aunque su
Jorge Rico Fontalvo Rico, Rodrigo Daza Anedo, María Raad Sarabia, Nehomar Pájaro Galvis, Ariel Bello Espinosa, Isabella, Christian Pérez Calvo, Alonso Pomares Lara, Zulay Mondol Almeida, Oscar Vergara Serpa, Carlos Berrocal Martinez, Luis Adolfo Collazos Torres, Karen Ruiz Pastrana   +12 more
doaj   +1 more source

Zymoseptoria tritici stealth infection is facilitated by stage‐specific downregulation of a β‐glucanase

New Phytologist, Volume 248, Issue 6, Page 3191-3207, December 2025.
Summary Plant cell walls constitute a major defence barrier against pathogens, although it is unclear how specific cell wall components impact pathogen colonisation. Pathogens secrete cell wall‐degrading enzymes (CWDEs) to facilitate plant colonisation, but damaged or infected cells are often a source of cell wall‐derived oligosaccharides that trigger ...
Diego Rebaque, Cristian Carrasco‐López, Parvathy Krishnan, Gemma López, Sergio López‐Cobos, Felipe de Salas, Lukas Meile, Cécile Lorrain, Asier Largo‐Gosens, Bruce A. McDonald, Francisco Vilaplana, María Jesús Martínez, Hugo Mélida, Antonio Molina, Andrea Sánchez‐Vallet   +14 more
wiley   +1 more source