Results 31 to 40 of about 361 (67)
Boletín Médico del Hospital Infantil de México, 2017 Introduction: Relapse occurs in approximately 20% of Mexican patients with childhood acute lymphoblastic leukemia (ALL). In this group, chemoresistance may be one of the biggest challenges.
Ana Laura Guzmán-Ortiz +5 more
doaj +1 more source
HLA‐B Serine 116 Confers Protection Against Severe COVID‐19 in a Cohort From Rio de Janeiro, Brazil
HLA, Volume 106, Issue 6, December 2025.ABSTRACT COVID‐19 is a respiratory disease caused by SARS‐CoV‐2, in which severe outcomes are primarily driven by an exacerbated immune response. The HLA region has been extensively investigated in COVID‐19 due to its central role in the immune response, although genetic associations vary across populations.
Maria Aparecida da Silva Pereira +15 more
wiley +1 more source
Rapid Communications in Mass Spectrometry, Volume 39, Issue 21, 15 November 2025.ABSTRACT Rationale Alpha‐hemoglobin stabilizing protein (AHSP) is an erythroid‐specific protein forming a stable complex with free α‐hemoglobin, but not with β‐hemoglobin or hemoglobin A (α2β2), thus preventing harmful aggregation of α‐hemoglobin during normal erythroid cell development and avoiding its pro‐oxidant activity.
Federica Iavarone +19 more
wiley +1 more source
Las "Ómicas" como herramienta en el estudio de la Salud Ambiental
Revista de Salud Ambiental, 2018 Las muertes provocadas por la contaminación ambiental son un problema de salud pública en incremento. La mayoría de las muertes prematuras provocadas por la contaminación son enfermedades no transmisibles, como enfermedad pulmonar obstructiva crónica ...
Claudia Muñoz Yañez +4 more
doaj +2 more sources
Omics-based biomarkers: current status and potential use in the clinic
Boletín Médico del Hospital Infantil de México, 2017 In recent years, the use of high-throughput omics technologies has led to the rapid discovery of many candidate biomarkers. However, few of them have made the transition to the clinic.
Héctor Quezada +4 more
doaj +1 more source
Chemical Biology &Drug Design, Volume 106, Issue 3, September 2025.An oxidated form of cacalol, the methylenecyclohexadienone MTC (2), is generated under highly oxidant conditions, thus emulating the environment present in cancer cells. This species (2) is responsible for the inhibition of tubulin polymerization by promoting an irreversible binding interaction with Cys347 in α‐tubulin.
Edgar López‐López +6 more
wiley +1 more source
Salud Pública de México, 2009 La resistencia bacteriana es un problema de salud pública causante de índices elevados de morbi-mortalidad hospitalaria. En la medida en que se usan los diferentes antibióticos se seleccionan bacterias resistentes a múltiples fármacos.
Ulises Garza-Ramos +2 more
doaj
Journal of Fungi, 2020 Background: Candida auris is characterized for having a high genetic variability among species. MALDI-TOF MS library contains spectra from only three strains of C.
Andrés Ceballos-Garzon +5 more
doaj +1 more source
Plant, Cell &Environment, Volume 48, Issue 9, Page 6874-6896, September 2025.ABSTRACT Plants have a wide range of adaptive and protective mechanisms to cope with dehydration. Central in these processes are the Late Embryogenesis Abundant (LEA) proteins, whose levels notably increase in response to dehydration during seed development and vegetative tissues.
Inti A. Arroyo‐Mosso +8 more
wiley +1 more source
The Journal of Pathology, Volume 265, Issue 4, Page 502-517, April 2025.Abstract Primary liver cancer usually occurs in the context of chronic liver disease (CLD), in association with fibrosis. Platelets have emerged as important regulators of CLD and liver cancer, although their precise function and mechanism of action need to be clarified. C3G (RapGEF1) regulates platelet activation, adhesion, and secretion.
Cristina Baquero +16 more
wiley +1 more source