Results 11 to 20 of about 361 (67)

Myosin 1g as a high-risk biomarker in a pediatric patient with lineage switch from acute lymphoblastic leukemia to myeloid phenotype

Boletín Médico del Hospital Infantil de México, 2023
Background: Myosin 1g (Myo1g) has recently been identified as a potential diagnostic biomarker in childhood acute lymphocytic leukemia (ALL). Case report: We describe the case of a 1-year-old Mexican female patient.
Janeth E. Araujo-Cárdenas, Miguel A. Rodríguez-Ruiz, Jaime A. López-Valdez, Rosa I. Rodríguez-Téllez, Yanelly Garfias-Gómez, Israel Parra-Ortega, Genaro Patiño-López   +6 more
doaj   +1 more source

Volatile Organic Compounds Emitted by Fungi Have Substantial Effects on Growth and Disease Resistance in Arabidopsis thaliana

Plant, Cell &Environment, EarlyView.
ABSTRACT Volatile organic compounds (VOCs) emitted by certain fungi have previously been suggested to modulate plant development and their response to stresses. While some fungal species, such as Trichoderma harzianum, are known to produce VOCs, the production of VOCs in other phylogenetically divergent species, such as Mucor mucedo, was previously ...
Sara Yugueros, Asier Largo‐Gosens, Cristina Úbeda, Cristina Hernández‐Fernández, Alba Manga‐Robles, Diego Rebaque, Antonio Encina, Hugo Mélida   +7 more
wiley   +1 more source

La aplicación de las ciencias bioforenses a la investigación del bioterrorismo y biocrimen

Ciencia Policial
En los últimos años las técnicas de biología molecular han experimentado un avance enorme en todos sus campos. Esto hace que las capacidades de análisis cualitativo, cuantitativo y de tiempos de procesamiento hayan mejorado mucho, en especial con la ...
Desiderio José Ordoño Ballesteros
doaj   +1 more source

Proteómica y biología de sistemas para el estudio de la alergia alimentaria

Arbor: Ciencia, Pensamiento y Cultura, 2020
La alergia alimentaria es el cuarto principal proble­ma de salud pública según datos de la Organización Mundial de la Salud (OMS). Afecta a un total de 6-8% de niños y a 2-4% de adultos.
Mónica Carrera
doaj   +1 more source

Proteoma urinario en la enfermedad renal diabética. Estado del arte

Revista Colombiana de Nefrología, 2021
La enfermedad renal diabética (ERD) es la principal complicación microvascular de los pacientes con diabetes mellitus; esta es una entidad que genera un aumento significativo en la mortalidad de origen cardiovascular de este grupo de pacientes, aunque su
Jorge Rico Fontalvo Rico, Rodrigo Daza Anedo, María Raad Sarabia, Nehomar Pájaro Galvis, Ariel Bello Espinosa, Isabella, Christian Pérez Calvo, Alonso Pomares Lara, Zulay Mondol Almeida, Oscar Vergara Serpa, Carlos Berrocal Martinez, Luis Adolfo Collazos Torres, Karen Ruiz Pastrana   +12 more
doaj   +1 more source

Extracellular Vesicles of Giardia duodenalis: Unravelling Their Virulence Factors and Potential to Induce Protection Against Experimental Giardiasis

Journal of Extracellular Biology, Volume 5, Issue 6, June 2026.
ABSTRACT Extracellular vesicles (EVs) are key mediators of intercellular communication, enabling trans‐kingdom exchange of proteins, nucleic acids, lipids, and metabolites. In Giardia duodenalis, EVs contribute to parasite survival, host–pathogen interactions, and immune modulation.
Corral‐Ruiz Gerardo, Argüello‐García Raúl, Ortiz‐Lozano Dalia, Salazar‐Villatoro Lizbeth, Pech‐Santiago Edar Onam, Espinosa‐Cantellano Martha, Hernández‐Cueto Daniel, Silva‐Olivares D. Angélica, Betanzos Abigail, Ortega‐Pierres M. Guadalupe   +9 more
wiley   +1 more source

Host–Pathogen Dual Targeting With Repurposed Drugs Identifies a Synergistic Therapy for Intracellular Staphylococcus aureus

MicrobiologyOpen, Volume 15, Issue 3, June 2026.
A large intracellular drug‐repurposing screen identifies a potent synergy between 5‐fluoro‐2′‐deoxycytidine and rifapentine, acting through dual host–pathogen targeting to reduce Staphylococcus aureus burdens across strains, cell types, and infection models (created with BioRender).
Blanca Lorente‐Torres, Helena Á. Ferrero, Pablo Castañera, Jesús Llano‐Verdeja, Sergio Fernández‐Martínez, Amanda Herrero‐González, Farzaneh Javadimarand, Roberto López, Jesús F. Aparicio, Andrew M. Edwards, Volker Behrends, Luis M. Mateos, Álvaro Mourenza, Michal Letek   +13 more
wiley   +1 more source

Biochemical Characterization of a Kunitz‐Type Protease Inhibitor From Mimosa regnellii and Its Effects on Melanoma Cell Viability and Angiogenesis

Chemistry &Biodiversity, Volume 23, Issue 4, April 2026.
A Kunitz‐type serine protease inhibitor (JTI) purified from Mimosa regnellii seeds selectively targets melanoma cells. JTI triggers mitochondrial apoptosis, increases ROS and Ca2+ levels, arrests the cell cycle, and suppresses migration and angiogenesis without affecting healthy cells.
Luciana Maria Araújo Rabêlo, Pedro Henrique de Oliveira Cardoso, Leonardo Thiago Duarte Barreto Nobre, Paula Ivani Medeiros dos Santos, Sheyla Varela Lucena, Raphael Paschoal Serquiz, Marcelo Porto Bemquerer, Hugo Alexandre de Oliveira Rocha, Helena Bonciani Nader, Elizeu Antunes dos Santos, Adeliana Silva de Oliveira, Breno Emanuel Farias Frihling, Ludovico Migliolo   +12 more
wiley   +1 more source

Amblyomma cajennense Sensu Stricto (Fabricius, 1787) and Amblyomma sculptum (Berlese, 1888) Tick Saliva Elicit Immune‐Modulatory Activity in Isolated Murine Macrophages With an Insight Into Proteomic Analysis

Parasite Immunology, Volume 48, Issue 3, March 2026.
ABSTRACT Tick saliva is known to cause immunosuppression and help pathogen transmission. Amblyomma sculptum is a public health concern as a vector of Rickettsia rickettsii. Another close‐related species is Amblyomma cajennense sensu stricto (s.s.). The impact of saliva from these species on murine macrophages remains unclear.
André de Abreu Rangel Aguirre, Valdison Pereira dos Reis, Sulamita da Silva Setúbal, Angélica Lorena Pereira Mendes Carioca, Ketlei Monteiro Tavares, Geisa Paulino Caprini Evaristo, Joseph Albert Medeiros Evaristo, Fábio César Sousa Nogueira, Jansen Fernandes Medeiros, Juliana Pavan Zuliani   +9 more
wiley   +1 more source

Molecular and Structural Characterization of Foam Proteins from Mahanarva spectabilis (Distant, 1909) (Hemiptera: Cercopidae) Nymphs Reveals Adaptive Features and Potential Targets for Pest Control

Archives of Insect Biochemistry and Physiology, Volume 121, Issue 2, February 2026.
Nymphs of Mahanarva spectabilis produce a protective foam that supports survival, reduces plant damage, and contributes to adult population establishment. Proteomic profiling combined with protein sequencing and structural modeling revealed foam proteins enriched in functional domains associated with environmental resilience.
Angelo José Rinaldi, Monique da Silva Bonjour, Ian de Paula Alves Pinto, Gabriely Teixeira Bhering Faria, Lucas Leal Lima, Marcela Chellini Pereira, Alexander Machado Auad, Jorge Fernando Pereira, Maria Goreti Almeida Oliveira, Humberto Josué de Oliveira Ramos   +9 more
wiley   +1 more source