Results 41 to 50 of about 8,586 (162)

Functional characterization of Fur from the strict anaerobe Clostridioides difficile provides insight into its redox‐driven regulatory capacity

open access: yesThe FEBS Journal, Volume 291, Issue 16, Page 3604-3627, August 2024.
Clostridioides (formerly Clostridium) difficile is a leading cause of infectious diarrhea. The ability of this pathogen to acquire enough iron in adverse conditions imposed by the host largely determines its pathogenicity. Iron homeostasis in C.
Ángela Fernández‐Otal   +6 more
wiley   +1 more source

The enigmatic enzyme ‘amidoxime reducing component’ of Lotus japonicus. Characterization, expression, activity in plant tissues, and proposed role as a nitric oxide‐forming nitrite reductase

open access: yesPhysiologia Plantarum, Volume 176, Issue 4, July/August 2024.
Abstract Human mitochondria contain a molybdoprotein capable of reducing amidoximes using cytochrome b5/cytochrome b5 reductase (Cb/CbR). This ‘amidoxime reducing component’ (ARC) also reduces nitrite to nitric oxide (NO). In the plant kingdom, distinct functions have been suggested for ARCs.
Samuel Minguillón   +4 more
wiley   +1 more source

Principios de laboratorio y aplicaciones en la práctica clínica de las técnicas moleculares, genómicas y proteómicas

open access: yesRevista Electrónica Dr. Zoilo E. Marinello Vidaurreta, 2014
La heterogénea expresión clínica de las enfermedades, la necesidad de la interpretación de los procesos fisiológicos y fisiopatológicos, así como la búsqueda incesante de nuevas estrategias diagnósticas y terapéuticas, han conducido al desarrollo de las ...
Jenny Hernández Betancourt   +1 more
doaj  

Omics-based biomarkers: current status and potential use in the clinic

open access: yesBoletín Médico del Hospital Infantil de México, 2017
In recent years, the use of high-throughput omics technologies has led to the rapid discovery of many candidate biomarkers. However, few of them have made the transition to the clinic.
Héctor Quezada   +4 more
doaj   +1 more source

Development and Validation of an in-House Library of Colombian Candida auris Strains with MALDI-TOF MS to Improve Yeast Identification

open access: yesJournal of Fungi, 2020
Background: Candida auris is characterized for having a high genetic variability among species. MALDI-TOF MS library contains spectra from only three strains of C.
Andrés Ceballos-Garzon   +5 more
doaj   +1 more source

Estudio preliminar de la expresión proteómica cerebral de la región hipocampal de ratas expuestas a diferentes niveles de estrés inducido por el nado forzado Preliminary study of cerebral proteomics expression of hippocampal region from rats exposed to different stress levels induced by forced swimming

open access: yesSalud UIS, 2012
Introducción: en general, los estímulos estresores pueden inducir respuestas adaptativas o mal adaptativas dependiendo, entre otras cosas, de su intensidad y la duración.
Guerrero Nasser   +2 more
doaj  

Biochemical characterization and gene structure analysis of the 24‐kDa glutathione transferase sigma from Taenia solium

open access: yesFEBS Open Bio, Volume 14, Issue 5, Page 726-739, May 2024.
Glutathione transferases (GST) are involved in detoxification and immunomodulation, allowing the establishment and development of cestodes in the host. Taenia solium has a 24‐kDa GST sigma class inducible gene that encodes a stable enzyme in a wide range of pHs and temperatures. Its enzymatic activity differs from other GSTs in the parasite, suggesting
Ricardo Miranda‐Blancas   +7 more
wiley   +1 more source

Análisis y aplicación del acoplamiento molecular de serotonina para la caracterización de dianas terapéuticas en trastornos depresivos

open access: yesRevista Colombiana de Biotecnología
La serotonina es un neurotransmisor encargado de muchas funciones dentro del cuerpo humano, además tiene gran influencia en el estado de ánimo de la persona.
Willington Londoño   +1 more
doaj   +1 more source

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