Results 161 to 170 of about 211,038 (237)

Structural basis of tethered agonism and G protein coupling of protease-activated receptors. [PDF]

Cell Res
Guo J, Zhou YL, Yang Y, Guo S, You E, Xie X, Jiang Y, Mao C, Xu HE, Zhang Y.   +9 more
europepmc   +1 more source

Possible Involvement of Thrombin/Protease-Activated Receptor 1 System in the Pathogenesis of Endometriosis [PDF]

, 2005
Yasushi Hirota, Yutaka Osuga, Tetsuya Hirata, Osamu Yoshino, Kaori Koga, Miyuki Harada, Chieko Morimoto, Emi Nose, Tetsu Yano, Osamu Tsutsumi, Yuji Taketani   +10 more
openalex   +1 more source

SiO2‐CaOCME/Poly(Tetrahydrofuran)/Poly(Caprolactone) 3D‐Printed Scaffolds Drive Human‐Bone Marrow Stromal Cell Osteogenic Differentiation

Advanced Healthcare Materials, EarlyView.
3D printed hybrid scaffolds combining bioactive silica–calcium chemistry with elastic polymers guide human bone stem cells to form bone. The scaffolds support cell survival, organization, and invasion while releasing osteogenic ions. Together, architecture and composition drive bone‐specific gene expression, extracellular matrix organization, and ...
David R. Sory, Agathe C.M. Heyraud, Julian R. Jones, Sara M. Rankin   +3 more
wiley   +1 more source

New insight into the agonism of protease-activated receptors as an immunotherapeutic strategy. [PDF]

J Biol Chem
Jiang Y, Lu L.
europepmc   +1 more source

Desensitisation of protease‐activated receptor‐1 (PAR‐1) in rat astrocytes: evidence for a novel mechanism for terminating Ca²⁺ signalling evoked by the tethered ligand

, 2000
Joachim J. Ubl, Marina G. Sergeeva, Georg Reiser   +2 more
openalex   +1 more source

Matrix metalloproteinases target protease-activated receptors on the tumor cell surface [PDF]

, 2005
Duanqing Pei
openalex   +1 more source

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

Characterizing Modulators of Protease-activated Receptors with a Calcium Mobilization Assay Using a Plate Reader. [PDF]

J Vis Exp
DeRousse JT, Dockendorff C.
europepmc   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

PH-binding motifs as a platform for drug design: Lessons from protease-activated receptors; PARs. [PDF]

Oncoscience
Nag JK, Hoffman A, Gilon C, Uziely B, Bar-Shavit R.   +4 more
europepmc   +1 more source