Results 241 to 250 of about 1,749,266 (388)

Autocatalytic Activity of the Ubiquitin-Specific Protease Domain of Herpes Simplex Virus 1 VP1-2

, 2011
M. Bolstad, Fernando Abaitua, Colin M. Crump, Peter O’Hare   +3 more
openalex   +2 more sources

Recent Progress in the Development of HIV-1 Protease Inhibitors for the Treatment of HIV/AIDS.

Journal of Medicinal Chemistry, 2016
Arun K. Ghosh, Heather L. Osswald, Gary Prato   +2 more
semanticscholar   +1 more source

Differential regulation of ZFAS1 splice variants by endoplasmic reticulum stress in hepatocyte cell lines

FEBS Open Bio, EarlyView.
ZFAS1 is a lncRNA promoting cell proliferation and migration, exhibiting high expression in various cancers. It is conserved, widely expressed, and produces multiple splice variants with unclear roles. We identified several splice variants in hepatocyte models, and found that inhibiting or suppressing regulators of the unfolded protein response (PERK ...
Sébastien Soubeyrand, Paulina Lau, Ruth McPherson   +2 more
wiley   +1 more source

HtrA2/Omi: potential therapeutic targets for neurodegenerative diseases. [PDF]

Front Pharmacol
Xu L, Zeng M.
europepmc   +1 more source

The Human CLN2 Protein/Tripeptidyl-Peptidase I Is a Serine Protease That Autoactivates at Acidic pH [PDF]

, 2001
Li Lin, István Sohár, Henry Lackland, Peter Lobel   +3 more
openalex   +1 more source

HIV‐1 establishes immediate latency in T cells expressing the viral Nef protein

FEBS Open Bio, EarlyView.
Nef is a viral protein often omitted from HIV‐1 reporter viruses. Consequently, its role in viral latency is unclear. We developed three novel dual reporter HIV‐1 derivatives that express Nef and allow for detection of latent and productive infection. Using these reporters, we show that Nef does not affect the establishment of immediate viral latency ...
Cindy Lam, Ivan Sadowski
wiley   +1 more source

Advancements in Functional Dressings and a Case for Cotton Fiber Technology: Protease Modulation, Hydrogen Peroxide Generation, and ESKAPE Pathogen Antibacterial Activity. [PDF]

Int J Mol Sci
Edwards JV, Prevost NT, Hinchliffe DJ, Nam S, Madison CA.   +4 more
europepmc   +1 more source

Activatable prodrug for controlled release of an antimicrobial peptide via the proteases overexpressed in Candida albicans and Porphyromonas gingivalis [PDF]

Lubna Amer, Maurice Retout, Jesse V. Jokerst   +2 more
openalex   +1 more source

Crystal structure of Zika virus NS2B-NS3 protease in complex with a boronate inhibitor

Science, 2016
Jian Lei, G. Hansen, Christoph Nitsche, C. Klein, Linlin Zhang, R. Hilgenfeld   +5 more
semanticscholar   +1 more source

Dapagliflozin prevents methylglyoxal‐induced retinal cell death in ARPE‐19 cells

FEBS Open Bio, EarlyView.
Diabetic macular oedema is a diabetes complication of the eye, which may lead to permanent blindness. ARPE‐19 are human retinal cells used to study retinal diseases and potential therapeutics. Methylglyoxal is a compound increased in uncontrolled diabetes due to elevated blood glucose.
Naina Trivedi, Zainab Quraishi, Shima Khezri Azizi Far, Madaleine Ward, Aidan Conway, Reem Abdulredha, Eman Mshari, Yousif A. Shamsaldeen   +7 more
wiley   +1 more source