Results 241 to 250 of about 580,293 (310)

Progress and Application of Multifunctional Hydrogel in Radioactive Skin Injury

open access: yesAdvanced Materials Interfaces, EarlyView.
This review examines healing challenges in radiation‐wound injuries, where ionizing radiation impairs immune and tissue repair processes. Hydrogels, with their biocompatibility, antimicrobial properties, and drug delivery capabilities, present a transformative solution. It compares hydrogel efficacy in radiation‐induced versus common wounds, highlights
Xinyue Cui   +5 more
wiley   +1 more source

Development of Photo‐Biocatalytic Redox System for Asymmetric Synthesis of Optically Active Amines Using Blue Light and Transaminases. A Case Study Toward Mavacamten

open access: yesAdvanced Synthesis &Catalysis, EarlyView.
Abstract α‐Chiral amines are versatile building blocks for the asymmetric synthesis of optically pure high‐added‐value chemicals, including pharmaceuticals, agrochemicals, and natural products. Herein, we report a one‐pot, two‐step sequential deracemization of racemic sec‐alcohols to optically enriched primary amines throught a photo‐biocatalytic ...
Natalia Antos   +5 more
wiley   +1 more source

Ammonia Dynamics in the Human Body: Insights in Biomedical Sensing Technologies

open access: yesAdvanced Sensor Research, EarlyView.
Ammonia (NH3) is a significant biomarker in diagnostics, affecting the respiratory system, stomach, liver, kidneys, bladder, and gastrointestinal tract. NH3 detection, using sensors, has the potential to improve medical diagnosis. This review examines recent advancements in NH3 sensing technologies and explores future research directions, including ...
Annelot Nijkoops   +8 more
wiley   +1 more source

Organic Transistor‐Based Biosensors for Viral RNA Detection and Variant Monitoring: From SARS‐CoV‐2 to Effective Management of Future Pandemics

open access: yesAdvanced Sensor Research, EarlyView.
A novel approach for direct sensing of viral RNA is proposed, allowing PCR‐free detection of viral RNA from genomic material, and variants screening by discrimination of polymorphic amplicons. The device is a cost‐effective, user‐friendly platform suitable for both mass screening kits and as a laboratory tool for an optimized management of resources ...
Stefano Lai   +4 more
wiley   +1 more source

Insights into the Dynamics and Binding Mechanisms of the Alkhumra Virus NS2B/NS3 Protease: A Molecular Dynamics Study

open access: yesAdvanced Theory and Simulations, EarlyView.
The ΔRMSF$\Delta {\rm RMSF}$ analysis reveals significant flexibility differences between free NS3 and the NS2B/NS3 complex, with notable deviations in specific regions. Key residues driving NS2B binding are identified, and the protonation state of catalytic serine affects oxyanion hole formation.
Jurica Novak   +2 more
wiley   +1 more source

FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron

open access: yesAdvanced Science, EarlyView.
This study aimed to unravel the role of FUS in the loading of functional circRNAs into neuronal sEVs under hypoxic conditions, which involves their aggregations in SGs and specific interaction between the FUS Zf_RanBP domain to regulate circRNA sorting in sEVs.
Jiankun Zang   +14 more
wiley   +1 more source

Purification of Protease from the Fungus Endothia parasitica

open access: bronze, 1968
Kris Hagemeyer   +2 more
openalex   +1 more source

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