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Protease Inhibitors in the Clinic
Medicinal Chemistry, 2005This review describes the clinical status (based on available information) of experimental drugs that inhibit enzymes called proteases, or more precisely a sub-class of proteases called peptidases that catalyse the hydrolysis of polypeptide main chain amide bonds.
Abbenante, Giovanni, Fairlie , David P.
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Proteases and protease inhibitors in cancer
Acta Histochemica, 1998The second conference on 'Proteases and protease inhibitors in cancer' was organized by the American Association for Cancer Research (AACR) and Acta Pathologica Microbiologica et Immunologica Scandinavica (APMIS). To understand the role of proteinases and to develop relevant synthetic inhibitors to stop or slow the progression of cancer, an integrated ...
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Protease inhibitor monotherapy
Current Opinion in Infectious Diseases, 2011The present review focuses on recent data about boosted protease inhibitor monotherapy for maintenance of HIV virological suppression.Until recently most of the trials of boosted protease inhibitor monotherapy have studied lopinavir/ritonavir monotherapy.
Ignacio, Pérez-Valero, Jose R, Arribas
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A study of proteases and protease-inhibitor complexes in biological fluids
Journal of Experimental Medicine, 1978E Reich
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Proteases and protease inhibitors in infectious diseases
Medicinal Research Reviews, 2018Allan Bernard Gamble +2 more
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