Results 281 to 290 of about 3,932,956 (396)

Coupling of an Acyl Migration Prodrug Strategy with Bio-activation To Improve Oral Delivery of the HIV-1 Protease Inhibitor Atazanavir

, 2018
Murugaiah A. M. Subbaiah, Nicholas A. Meanwell, John F. Kadow, Lakshumanan Subramani, Mathiazhagan Annadurai, Thangeswaran Ramar, Salil D. Desai, Sarmistha Halder Sinha, Murali Subramanian, Sandhya Mandlekar, Srikanth Sridhar, Shweta Padmanabhan, Priyadeep Bhutani, Rambabu Arla, Susan M. Jenkins, Mark Krystal, Chunfu Wang, Ramakanth Sarabu   +17 more
openalex   +1 more source

The Involvement of Cysteine Proteases and Protease Inhibitor Genes in the Regulation of Programmed Cell Death in Plants

The Plant Cell, 1999
M. Solomon, B. Belenghi, M. Delledonne, E. Menachem, A. Levine   +4 more
semanticscholar   +1 more source

Synergistic All‐in‐One Electroceutical Platform Utilizing a Plasma–Photodynamic Hybrid Approach for Enhanced Wound Healing

Advanced Functional Materials, EarlyView.
A flexible hybrid patch integrating a robust cold atmospheric plasma (CAP) system with a high‐power, ultrathin bio‐OLED was developed to enable synergistic wound healing. This multimodal therapy, combining plasma and photodynamic treatment, enhanced angiogenesis, cell proliferation, and collagen deposition, demonstrating superior in vivo efficacy and ...
Jun‐Yeop Song, Hyun Cheol Bang, Young Hyun Son, Dae‐In Ha, Eun‐Ju Hong, Sun‐Woo Lee, Jeongsook Kim, Doyeong Kim, Sang‐Min Park, Kyu Pil Lee, Hyo‐Jung Kwon, Jeong Hyun Kwon   +11 more
wiley   +1 more source

A major Toxoplasma serine protease inhibitor protects the parasite against gut-derived serine proteases and NETosis damage. [PDF]

J Biol Chem
Saffarian M, Romano JD, Grigg ME, Coppens I.   +3 more
europepmc   +1 more source

HIV-1 Protease Mutations and Protease Inhibitor Cross-Resistance

Antimicrobial Agents and Chemotherapy, 2010
Soo-Yon Rhee, Jonathan Taylor, W. J. Fessel, D. Kaufman, W. Towner, P. Troia, P. Ruane, J. Hellinger, V. Shirvani, A. Zolopa, R. Shafer   +10 more
semanticscholar   +1 more source

Inhibiting protease-activity in peptidomics: strategies during sampling and receptor studies [PDF]

, 2008
Burvenich, Christian, De Spiegeleer, Bart, Pezeshki, Adel, Van Dorpe, Sylvia, Vergote, Valentijn   +4 more
core  

Membrane Fusion‐Inspired Nanomaterials: Emerging Strategies for Infectious Disease and Cancer Diagnostics

Advanced Healthcare Materials, EarlyView.
Membrane fusion‐inspired nanomaterials offer transformative potential in diagnostics by mimicking natural fusion processes to achieve highly sensitive and specific detection of disease biomarkers. This review highlights recent advancements in nanomaterial functionalization strategies, signal amplification systems, and stimuli‐responsive fusion designs,
Sojeong Lee, Khulan Nyamzaya, Jueun Han, Yejin Song, Jihee Lee, Jung Hyun Jo, Seungmin Bang, Eun‐Kyung Lim, Seungjoo Haam, Eunjung Kim   +9 more
wiley   +1 more source

Discovery of the Clinical Candidate <b>S-892216</b>: A Second-Generation of SARS-CoV-2 3CL Protease Inhibitor for Treating COVID-19. [PDF]

J Med Chem
Unoh Y, Hirai K, Uehara S, Kawashima S, Nobori H, Sato J, Shibayama H, Hori A, Nakahara K, Kurahashi K, Takamatsu M, Yamamoto S, Zhang Q, Tanimura M, Dodo R, Maruyama Y, Sawa H, Watari R, Miyano T, Kato T, Sato T, Tachibana Y.   +21 more
europepmc   +1 more source

Membrane Vesicles from Lacticaseibacillus Casei BL23 Exhibit Antimicrobial Activity Against Escherichia coli and Immunostimulatory Effects on Human Peripheral Blood Mononuclear Cells

Advanced Healthcare Materials, EarlyView.
Membrane vesicles derived from the probiotic Lacticaseibacillus casei BL23 demonstrate antimicrobial properties against Escherichia coli and a potential biological effect in improving the overall survival of C. elegans infected with Pseudomonas aeruginosa. These vesicles stimulated immune responses in primary cells without causing toxicity. Our results
Cecilia L. D'Antoni, Leila Pourtalebi Jahromi, Lorenzo Sana, Ana Paula Domínguez Rubio, Maja Dorfner, Jennifer Munkert, Heike Danzer, Philipp Arnold, Mikhail Lebedev, Esther Zanin, Oscar E. Pérez, Gregor Fuhrmann   +11 more
wiley   +1 more source

Efficacy of a cysteine protease inhibitor compared with enalapril in murine heart failure models. [PDF]

iScience
Aluja D, Delgado-Tomás S, Barrabés JA, Miró-Casas E, Ruiz-Meana M, Rodríguez-Sinovas A, Benito B, Wang J, Song LS, Ferreira-González I, Inserte J.   +10 more
europepmc   +1 more source