Results 11 to 20 of about 3,573,509 (380)

Protease Inhibitors from Marine Venomous Animals and Their Counterparts in Terrestrial Venomous Animals [PDF]

Marine Drugs, 2013
The Kunitz-type protease inhibitors are the best-characterized family of serine protease inhibitors, probably due to their abundance in several organisms.
Caroline B. F. Mourão, Elisabeth F. Schwartz   +1 more
doaj   +6 more sources

Susceptibility of HPV-18 Cancer Cells to HIV Protease Inhibitors [PDF]

Viruses
Cervical cancer cases continue to rise despite all the advanced screening and preventative measures put in place, which include human papillomavirus (HPV) vaccination.
Lilian Makgoo, Salerwe Mosebi, Zukile Mbita   +2 more
doaj   +2 more sources

Role of Protease-Inhibitors in Ocular Diseases

Molecules, 2014
It has been demonstrated that the balance between proteases and protease-inhibitors system plays a key role in maintaining cellular and tissue homeostasis. Indeed, its alteration has been involved in many ocular and systemic diseases.
Nicola Pescosolido, Andrea Barbato, Antonia Pascarella, Rossella Giannotti, Martina Genzano, Marcella Nebbioso   +5 more
doaj   +2 more sources

Protease Inhibitors in Tick Saliva: The Role of Serpins and Cystatins in Tick-host-Pathogen Interaction

Frontiers in Cellular and Infection Microbiology, 2017
The publication of the first tick sialome (salivary gland transcriptome) heralded a new era of research of tick protease inhibitors, which represent important constituents of the proteins secreted via tick saliva into the host.
Jindřich Chmelař, Jan Kotál, Jan Kotál, Helena Langhansová, Helena Langhansová, Michail Kotsyfakis   +5 more
doaj   +2 more sources

Protease inhibitors. 2. Bacterial proteases and their inhibitors [PDF]

Biochemical Journal, 1949
E. S. Duthie, L. Lorenz
openalex   +4 more sources

Restriction of Viral Glycoprotein Maturation by Cellular Protease Inhibitors [PDF]

Viruses
The human genome is estimated to encode more than 500 proteases performing a wide range of important physiological functions. They digest proteins in our food, determine the activity of hormones, induce cell death and regulate blood clotting, for example.
Rishikesh Lotke, Moritz Petersen, Daniel Sauter   +2 more
doaj   +2 more sources

HIV protease inhibitors: a review of molecular selectivity and toxicity

HIV/AIDS: Research and Palliative Care, 2015
Zhengtong Lv,* Yuan Chu,* Yong Wang Department of Immunology, School of Basic Medical Science, Xiangya School of Medicine, Central South University, Changsha, Hunan, People's Republic of China *Both authors contributed equally to this work ...
Lv Z, Chu Y, Wang Y
doaj   +2 more sources

Gastric Proteases and Protease Inhibitors

Gastroenterology, 1967
Michael D. Turner, Leon L. Miller, Harry L. Segal   +2 more
openalex   +3 more sources

Developing HIV-1 Protease Inhibitors through Stereospecific Reactions in Protein Crystals [PDF]

Molecules, 2016
Protease inhibitors are key components in the chemotherapy of HIV infection. However, the appearance of viral mutants routinely compromises their clinical efficacy, creating a constant need for new and more potent inhibitors.
Folasade M. Olajuyigbe, Nicola Demitri, Rita De Zorzi, Silvano Geremia   +3 more
doaj   +3 more sources

Development of small molecule non-covalent coronavirus 3CL protease inhibitors from DNA-encoded chemical library screening [PDF]

Nature Communications
Variants of SARS-CoV-2 have continued to emerge across the world and cause hundreds of deaths each week. Due to the limited efficacy of vaccines against SARS-CoV-2 and resistance to current therapies, additional anti-viral therapeutics with pan ...
Hengrui Liu, Arie Zask, Farhad Forouhar, Sho Iketani, Alana Williams, Daniel R. Vaz, Dahlya Habashi, Karenna Choi, Samuel J. Resnick, Seo Jung Hong, David H. Lovett, Tian Bai, Alejandro Chavez, David D. Ho, Brent R. Stockwell   +14 more
doaj   +2 more sources