Results 161 to 170 of about 558,985 (342)
FEBS Open Bio, EarlyView.Representation of the suggested mode of action of lactoferrin (Lf) in nonsmall cell lung cancer (NSCLC) A549 cells. Lf induces activation of caspase‐3 by activating p53 and AChE leading to decreased ACh concentrations. In turn, ACh signaling leads to activation of VEGF and AKT and blocking of caspase‐3.
Stuti Goel +9 more
wiley +1 more source
Hepatitis C virus NS3-4A protease regulates the lipid environment for RNA replication by cleaving host enzyme 24-dehydrocholesterol reductase [PDF]
, 2020 Lorillee Tallorin +8 more
openalex +1 more source
Exploration of Compost Soil for the Production of Thermo-Stable Bacillus Protease to Synthesize Bioactive Compounds through Soy Protein Hydrolysis [PDF]
, 2023 Ieshita Pan +7 more
openalex +1 more source
[Proteases and protease antagonists in neoplasms].
Nowotwory, 1991 The maintenance of equilibrium between proteases and their inhibitors has substantial significance for the pathogenesis of the neoplastic disease. It concerns especially the invasiveness of the neoplasms, which increases with rising of the proteases activity or with the decrease of the inhibitory activity of antiproteases.
J, Prokopowicz, M, Dabrowska, H, Kemona
openaire +1 more source
FEBS Open Bio, EarlyView.CDT1 is an essential protein for DNA replication licensing that loads the MCM complex, the eukaryotic replicative DNA helicase, onto replication origins. Overexpression of CDT1 induces cell cycle arrest at the S phase. Here we showed CDT1 inhibits the progression of replication forks by interacting with the MCM complex, leading to the stalling and ...
Takashi Tsuyama +7 more
wiley +1 more source
Impaired fertility in mice deficient for the testicular germ-cell protease PC4
, 1997 Majambu Mbikay +11 more
openalex +2 more sources
HSP70 governs permeability and mechanotransduction in primary human endothelial cells
FEBS Open Bio, EarlyView.HSP70 chemical inhibition reduces endothelial cell proliferation and increases permeability, the latter supported by normal interendothelial junctional protein distribution. HSP70 also plays a role in shear stress response, a hemodynamic force naturally present in blood vessels and correlated with vessel protection.
Andrea Pinto‐Martinez +5 more
wiley +1 more source
Homologous expression and purification of human HAX‐1 for structural studies
FEBS Open Bio, EarlyView.This research protocol provides detailed instructions for cloning, expressing, and purifying large quantities of the intrinsically disordered human HAX‐1 protein, N‐terminally fused to a cleavable superfolder GFP, from mammalian cells. HAX‐1 is predicted to undergo posttranslational modifications and to interact with membranes, various cellular ...
Mariana Grieben
wiley +1 more source
Transmembrane protease serine 5: a novel Schwann cell plasma marker for CMT1A
, 2019 Hongge Wang +18 more
openalex +1 more source