Results 171 to 180 of about 563,257 (338)

NEMF-mediated Listerin-independent mitochondrial translational surveillance by E3 ligase Pirh2 and mitochondrial protease ClpXP [PDF]

Liang Lv, Jinyou Mo, Yumin Qing, Shuchao Wang, Leijie Chen, Anna Mei, Ru Xu, Hualin Huang, Jieqiong Tan, Yifu Li, Jia Liu   +10 more
openalex   +1 more source

Establishment of a coculture system for Porphyromonas gingivalis and head and neck squamous cell carcinoma using spheroid culture and LATS inhibition

FEBS Open Bio, EarlyView.
We established a spheroid coculture system enabling viable Porphyromonas gingivalis–HNSCC interactions under normoxic conditions. Inhibition of LATS1/2 maintains tumor cells in an undifferentiated state, which may promote spheroid growth and create a more permissive environment for bacterial persistence.
Yurika Nakajima, Shogo Okazaki, Muneaki Tamura, Shuichi Sato, Kenichi Imai   +4 more
wiley   +1 more source

SARS-CoV-2 and oncolytic EV-D68-encoded proteases differentially regulate pyroptosis [PDF]

Siyu Shen, Haoran Guo, Yan Li, Lili Zhang, Tang Yu-bin, Huili Li, Xiaohan Li, Pei‐Hui Wang, Xiao‐Fang Yu, Wei Wei   +9 more
openalex   +1 more source

Tối ưu các điều kiện sinh enzyme protease ngoại bào của vi khuẩn Streptomyces DH3.4

, 2021
Phạm Thị Tuyết Ngân, Hùng Hải Vũ, Huỳnh Trường Giang, Vũ Ngọc Út   +3 more
openalex   +2 more sources

The association between trypsin‐like protease activity in the oral cavity and kidney function in Japanese workers [PDF]

, 2023
Masanori Iwasaki, Maki Inoue, Michihiko Usui, Wataru Ariyoshi, Keisuke Nakashima, Yoshie Nagai‐Yoshioka, Tatsuji Nishihara   +6 more
openalex   +1 more source

DDX3X induces mesenchymal transition of endothelial cells by disrupting BMPR2 signaling

FEBS Open Bio, EarlyView.
Elevated DDX3X expression led to downregulation of BMPR2, a key regulator of endothelial homeostasis and function. Our co‐immunoprecipitation assays further demonstrated a molecular interaction between DDX3X and BMPR2. Notably, DDX3X promoted lysosomal degradation of BMPR2, thereby impairing its downstream signaling and facilitating endothelial‐to ...
Yu Zhang, Jing Wang, De‐Hui Qian, Yang‐Fan Lv, Tian‐Le Cheng, Da‐Peng Wang, Jing Zhang, Ye Fan   +7 more
wiley   +1 more source

Changes in γ-secretase activity and specificity caused by the introduction of consensus aspartyl protease active motif in Presenilin 1 [PDF]

, 2008
Donald B. Carter, Edwige Dunn, Adele M. Pauley, Denise D. McKinley, Timothy J. Fleck, Brenda R Ellerbrook, Nancy C. Stratman, Xiangdong Zhou, Carol S. Himes, Jeffrey S. Nye, Alfredo G. Tomasselli, Riqiang Yan   +11 more
openalex   +1 more source

"Maturation of the SARS-CoV-2 virus is regulated by dimerization of its main protease" TPR files

, 2021
Shreyas Kaptan, Mykhailo Girych, Giray Enkavi, Waldemar Kulig, Vivek Sharma, Joni Vuorio, Tomasz Róg, Ilpo Vattulainen   +7 more
openalex   +2 more sources

ATP13A2 is involved in intracellular polyamine transport in lung epithelial cells

FEBS Open Bio, EarlyView.
Spermidine transport in lung epithelial cells involves the polyamine transporter ATP13A2. Cell proliferation is associated with the upregulation of ATP13A2. Polyamines are present in all living cells and are implicated in various crucial cellular processes such as proliferation, apoptosis and autophagy.
Yuta Hatori, Kohei Kawabata, Takanori Kubo, Takeo Kitazawa, Sae Kanai, Madoka Iwashita, Ami Hayashi, Hiroyuki Nishi, Mikihisa Takano   +8 more
wiley   +1 more source

Supplementary Figure S9 from Mitochondrial Matrix Protease ClpP Agonists Inhibit Cancer Stem Cell Function in Breast Cancer Cells by Disrupting Mitochondrial Homeostasis

, 2023
Yoshimi Endo Greer, Lídia Hernandez, Emily M.J. Fennell, Manjari Kundu, Donna Voeller, Raj Chari, Samuel F. Gilbert, Thomas S.K. Gilbert, Shashikala Ratnayake, Binwu Tang, Markus Hafner, Qingrong Chen, Daoud Meerzaman, Edwin J. Iwanowicz, Christina M. Annunziata, Lee M. Graves, Stanley Lipkowitz   +16 more
openalex   +1 more source