Results 241 to 249 of about 331,217 (249)

Using High‐Throughput Screening to Identify Crosslinking Peptides That Control Cell‐Mediated Matrix Degradation

Advanced Healthcare Materials, EarlyView.
Protease‐degradable hydrogels mimic dynamic cell‐matrix interactions, but controlling hydrogel degradation is a challenge. We screen libraries of peptides to identify sequences that are primarily degraded by membrane‐localized proteases. Crosslinking hydrogels with these peptides enables cell to spread and migrate while reducing matrix degradation ...
Yingjie Wu, Samuel J. Rozans, Abolfazl Salehi Moghaddam, E. Thomas Pashuck   +3 more
wiley   +1 more source

Macrocyclic Phage Display for Identification of Selective Protease Substrates. [PDF]

J Am Chem Soc
Faucher FF, Blažková K, Lovell S, Bertolini M, Herrero-Bourdieu J, Cosco ED, Bogyo M, Barniol-Xicota M.   +7 more
europepmc   +1 more source

Inhalability and Bioactivity of Spray‐Dried versus Pressurized Gas eXpanded Liquid Technology‐Processed Yeast Beta‐Glucan Microparticles for Anti‐Fibrotic Therapies

Advanced Healthcare Materials, EarlyView.
PGXTEC) liquid technology is utilized to develop highly respirable yeast beta‐glucan (YBG) microparticles for the treatment of pulmonary fibrosis. Compared to conventionally processed spray‐dried YBG, PGXTEC‐YBG exhibits greatly improved aerodynamic properties, enhanced pro‐fibrotic macrophage uptake, and effective downregulation of pro‐fibrotic ...
Nate Dowdall, Safaa Naiel, Quan Zhou, Pareesa Ali, Tamana Rubina Yousof, Emily Wong, Ricardo Couto, Byron Yépez, Bernhard Seifried, Paul Moquin, Rod Rhem, Myrna Dolovich, Martin Rainer Kolb, Kjetil Ask, Todd Hoare   +14 more
wiley   +1 more source

Evolution of the SARS-CoV-2 spike protein in utilizing host transmembrane serine proteases. [PDF]

iScience
Milewska A, Cofas-Vargas LF, Poma AB, Pyrć K.   +3 more
europepmc   +1 more source

A Simple, Quick, and Scalable Route to Fluorogenic Ubiquitin and Ubiquitin-Like Protein Substrates for Assessing Activities of Deubiquitinases and Ubiquitin-Like Protein-Specific Proteases. [PDF]

ACS Chem Biol
Chanda S, Pham A, Shi Y, Atla S, Liu WR.
europepmc   +1 more source

Neutrophil dysfunction in bronchiectasis: Pathophysiological insights and emerging targeted therapies. [PDF]

Multidiscip Respir Med
Taha A.
europepmc   +1 more source

Optimization of protease production by newly isolated Bacillus sp. from the Red Sea using defatted soybean cake. [PDF]

Sci Rep
Amin OE, Aboul-Enein AM, Abd-Elsalam IS, Wahba MI, Helmy YS.   +4 more
europepmc   +1 more source

Substrate Specificity and Peptide Motif Preferences of β-Lytic and L5 Proteases from <i>Lysobacter</i> spp. Revealed by LC-MS/MS Analysis. [PDF]

Int J Mol Sci
Konstantinov M, Kaluzhskiy L, Yablokov E, Zhdanov D, Ivanov A, Toropygin I.   +5 more
europepmc   +1 more source