Results 221 to 230 of about 393,592 (390)

Protocol for analysis of intracellular conversion of artezomib molecules into new proteasome inhibitors in Plasmodium falciparum parasites

STAR Protocols
Summary: Artezomibs (ATZs), dual-pharmacophore molecules comprising of artemisinin and a parasite proteasome inhibitor, hijack parasite ubiquitin proteasome system to transform into new proteasome inhibitors following the activation of artemisinin by ...
Wenhu Zhan, Yi Jing Liu, Laura A. Kirkman, Gang Lin   +3 more
doaj  

Proteasome caspase-like activity regulates stress granules and proteasome condensates. [PDF]

Front Cell Dev Biol
Steinberger S, Adler J, Myers N, Shaul Y.   +3 more
europepmc   +1 more source

Yeast Cycloheximide-resistantcrlMutants Are Proteasome Mutants Defective in Protein Degradation

, 1997
Uwe-M. Gerlinger, Roland Gückel, Michael Hoffmann, Dieter H. Wolf, Wolfgang Hilt   +4 more
openalex   +2 more sources

‘ER degradation’ of a mutant yeast plasma membrane protein by the ubiquitin‐proteasome pathway [PDF]

, 1998
Jean‐Marc Galan, B. Cantegrit, Catherine Garnier, Olivier Namy, Rosine Haguenauer‐Tsapis   +4 more
openalex   +1 more source

Akkermansia Muciniphila Alleviates Severe Acute Pancreatitis via Amuc1409‐Ube2k‐Foxp3 Axis in Regulatory T Cells

Advanced Science, EarlyView.
Akkermansia depletion correlates with acute pancreatitis (AP) severity. A. muciniphila and its protein Amuc_1409 mitigate pancreatic/systemic inflammation by expanding Tregs and IL‐10. Mechanistically, Amuc_1409 binds Ube2k, inhibiting Foxp3 ubiquitination to stabilize Treg differentiation and IL‐10 production, countering SAP‐induced SIRS/CARS ...
Jinyan Xie, Lijun Du, Yunkun Lu, Xiuliu Guo, Xinyuan Zhou, Yifan Tong, Bo Shen, Xin Yu, Feng Guo, Hong Yu   +9 more
wiley   +1 more source

Not Just PA28γ: What We Know About the Role of PA28αβ in Carcinogenesis. [PDF]

Biomolecules
Cascio P.
europepmc   +1 more source

Mammalian Sug1 and c-Fos in the nuclear 26S proteasome.

, 1996
Weidong Wang, Pierre M. Chevray, Daniel Nathans   +2 more
openalex   +1 more source

The Expression of the Protochordate Homologue of the Proteasome Regulatory Subunit Rpn12 is Transcriptionally and Post-translationally Regulated during Cleavage Stage [PDF]

, 1999
Michiko Wada, Akikazu R. Murakami, Hiroshi Kawamura, R. Nakamori, Kimio Tanaka, Hiroki Nakayama, Takahito Nishikata   +6 more
openalex   +1 more source

A large fraction of HLA class I ligands are proteasome-generated spliced peptides

Science, 2016
Juliane Liepe, F. Marino, J. Sidney, Anita Jekő, Daniel E. Bunting, A. Sette, P. Kloetzel, M. Stumpf, A. Heck, M. Mishto   +9 more
semanticscholar   +1 more source

PIP5K1A Suppresses Ferroptosis and Induces Sorafenib Resistance by Stabilizing NRF2 in Hepatocellular Carcinoma

Advanced Science, EarlyView.
Inducing ferroptosis is a promising strategy for combating tumor resistance. Upregulated PIP5K1A competes with NRF2 for KEAP1 binding, which decreases the ubiquitination degradation of NRF2 and promotes its nuclear translocation, thereby suppressing ferroptosis, and ultimately driving hepatocellular carcinoma (HCC) tumorigeneses and sorafenib ...
Mengzhou Guo, Sinuo Chen, Jialei Sun, Ruchen Xu, Zhuoran Qi, Jie Li, Lianer Zhou, Yuan Fang, Tianshu Liu, Jinglin Xia   +9 more
wiley   +1 more source