Comparative proteomic profiling reveals molecular characteristics associated with oogenesis and oocyte maturation during ovarian development of Bactrocera dorsalis (Hendel) [PDF]
, 2017 Time-dependent expression of proteins in ovary is important to understand oogenesis in insects. Here, we profiled the proteomes of developing ovaries from Bactrocera dorsalis (Hendel) to obtain information about ovarian development with particular ...
Wei, Dong +6 more
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Amyloid-Beta Protein Clearance and Degradation (ABCD) Pathways and their Role in Alzheimer’s Disease [PDF]
, 2015 Amyloid-β proteins (Aβ) of 42 (Aβ42) and 40 aa (Aβ40) accumulate as senile plaques (SP) and cerebrovascular amyloid protein deposits that are defining diagnostic features of Alzheimer's disease (AD). A number of rare mutations linked to familial AD (FAD)
Baranello, Robert J. +7 more
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, 2012 Chemical cross-linking in combination with mass spectrometric analysis offers the potential to obtain low-resolution structural information from proteins and protein complexes. Identification of peptides connected by a cross-link provides direct evidence
Aebersold, R. +6 more
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Thimet oligopeptidase (EC 3.4.24.15) key functions suggested by knockout mice phenotype characterization [PDF]
, 2019 Thimet oligopeptidase (THOP1) is thought to be involved in neuropeptide metabolism, antigen presentation, neurodegeneration, and cancer. Herein, the generation of THOP1 C57BL/6 knockout mice (THOP1(-/-)) is described showing that they are viable, have ...
Abilio, V.C. +26 more
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Insights into the regulation of intrinsically disordered proteins in the human proteome by analyzing sequence and gene expression data [PDF]
, 2009 Background: Disordered proteins need to be expressed to carry out specified functions; however, their accumulation in the cell can potentially cause major problems through protein misfolding and aggregation.
Edwards, Y.J.K. +3 more
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Exogenous abscisic acid treatment regulates protein secretion in sorghum cell suspension cultures. [PDF]
, 2023 Drought stress adversely affects plant growth, often leading to total crop failure. Upon sensing soil water deficits, plants switch on biosynthesis of abscisic acid (ABA), a stress hormone for drought adaptation.
Brown, Adrian P +5 more
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Proteasome and immunoproteasome function in cigarette smoke-mediated chronic lung disease [PDF]
, 2016 Chronic obstructive pulmonary disease (COPD) is projected to be the third leading cause of death by 2020 with cigarette smoke exposure being the main risk factor.
Kammerl, Ilona
core
A Supercode for Inflammation [PDF]
, 2004 Siegelman and colleagues demonstrate unexpected synergism of CD44 and VLA-4 during lymphocyte extravasation. This is the first time that molecules mediating rolling and firm adhesion have been shown to associate biochemically leading to direct functional
Dustin, Michael
core +1 more source
Protease gene families in Populus and Arabidopsis [PDF]
, 2006 BACKGROUND: Proteases play key roles in plants, maintaining strict protein quality control and degrading specific sets of proteins in response to diverse environmental and developmental stimuli.
Funk, Christiane +3 more
core +3 more sources
Ricin B chain targeted to the endoplasmic reticulum of tobacco protoplasts is degraded by a CDC48- and vacuole-independent mechanism [PDF]
, 2008 The B chain of ricin was expressed and delivered to the endoplasmic reticulum of tobacco protoplasts where it disappeared with time in a manner consistent with degradation. This turnover did not occur in the vacuoles or upon secretion.
Asher +73 more
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