Results 161 to 170 of about 469,365 (378)

Synthesis of PEG-PLA Block Copolymer Nanospheres Containing Mixed Recombinant Proteins of Protective Antigen and Lethal Factor of Bacillus anthracis

Majallah-i Dānishgāh-i ’Ulūm-i Pizishkī-i Īlām, 2021
Introduction: Anthrax is a zoonotic disease and vaccine production is one way to protect people against this bacterium. This study investigates the application of copolymer nanocapsule (PEG-PLA) systems with controlled release specificity for a ...
Hossein Honari, Mohammad Ebrahim Minaei, Hassan Mirhaj, Sayyed Masih Etemadaubi   +3 more
doaj  

Process development and preclinical evaluation of a major Plasmodium falciparum blood stage vaccine candidate, Cysteine-Rich Protective Antigen (CyRPA). [PDF]

Front Immunol, 2022
Somanathan A, Mian SY, Chaddha K, Uchoi S, Bharti PK, Tandon R, Gaur D, Chauhan VS.   +7 more
europepmc   +1 more source

Cross-Protective Antigens of Neisseria meningitidis Obtained from Slaterus Group Y [PDF]

, 1972
Harold J. Jennings, A.M. Martin, C. P. Kenny, B. B. Diena   +3 more
openalex   +1 more source

“Therapies Through Gut:” Targeted Drug Delivery for Non‐Gastrointestinal Diseases by Oral Administration

Advanced Healthcare Materials, EarlyView.
Schematic illustration of the mechanism of targeted delivery of nanoparticles including 1) paracellular, 2) endolysosomal escape, 3) receptor mediated endocytosis, and 4) M cell mediated transport for non‐GI diseases by oral administration such as atherosclerosis, cancer, diabetes, and brain diseases. Abstract Oral drug delivery is a promising approach
Subarna Ray, Shehzahdi S. Moonshi, Hang Thu Ta   +2 more
wiley   +1 more source

Solubilization and Characterization of a Protective Antigen of Erysipelothrix rhusiopathiae [PDF]

, 1970
R. R. White, W. F. Verwey
openalex   +1 more source

Novel Less Toxic, Lymphoid Tissue‐Targeted Lipid Nanoparticles Containing a Vitamin B5‐Derived Ionizable Lipid for mRNA Vaccine Delivery

Advanced Healthcare Materials, Volume 14, Issue 7, March 14, 2025.
The top‐performing lipid nanoparticle, incorporating a novel ionizable lipid derived from vitamin B5, demonstrates high mRNA transfection efficiency, low toxicity, favorable stability, targeted delivery to lymphoid tissues, and high immunogenicity, showing promise as a carrier for mRNA vaccines for infectious diseases and cancer.
Soyeon Yoo, Muhammad Faisal, Seo‐Hyeon Bae, Kounghwa Youn, Hyo‐Jung Park, Sung Pil Kwon, Il Kwon Hwang, Jisun Lee, Hyeong Jun Kim, Jae‐Hwan Nam, Gyochang Keum, Eun‐Kyoung Bang   +11 more
wiley   +1 more source

Retraction: A Femtomol Range FRET Biosensor Reports Exceedingly Low Levels of Cell Surface Furin: Implications for the Processing of Anthrax Protective Antigen. [PDF]

PLoS One, 2022
PLOS ONE Editors.
europepmc   +1 more source

Relation-Aware Equivariant Graph Networks for Epitope-Unknown Antibody Design and Specificity Optimization [PDF]

arXiv
Antibodies are Y-shaped proteins that protect the host by binding to specific antigens, and their binding is mainly determined by the Complementary Determining Regions (CDRs) in the antibody. Despite the great progress made in CDR design, existing computational methods still encounter several challenges: 1) poor capability of modeling complex CDRs with
arxiv  

Solubilization of the protective antigens of Bordetella pertussis [PDF]

, 1979
A. Robinson
openalex   +1 more source

TPMS‐Gyroid Scaffold‐Mediated Up‐Regulation of ITGB1 for Enhanced Cell Adhesion and Immune‐Modulatory Osteogenesis

Advanced Healthcare Materials, EarlyView.
A) SLM generates biomimetic bone scaffolds with consistent porosity but varying TPMS‐Gyroid unit cell designs (TG15, TG20, TG25, TG30). B) By enhancing the expression of ITGB1, TPMS‐Gyroid scaffolds can facilitate osteogenic differentiation in BMSCs and promote M2 polarization in macrophages.
Jing Wang, Zenan Huang, Zhenzhong Han, Jing Luan, Zihan Li, Xutong Guo, Dongxu Yang, Yazhou Cui, Jinxiang Han, Duo Xu   +9 more
wiley   +1 more source