Results 181 to 190 of about 527,152 (301)

Evaluating the Immunogenicity of a Recombinant Bacillus subtilis Expressing LTB-Fused Protective Antigen of Transmissible Gastroenteritis Virus in a Murine Model. [PDF]

Biology (Basel)
Fan R, Bi Y, Yang S, Yao S, An W, Wang Z, Ma Z, Rui P, Song T, Wang L, Li F.   +10 more
europepmc   +1 more source

Anthrax toxin component, Protective Antigen, protects insects from bacterial infections. [PDF]

PLoS Pathog, 2020
Alameh S, Bartolo G, O'Brien S, Henderson EA, Gonzalez LO, Hartmann S, Klimko CP, Shoe JL, Cote CK, Grill LK, Levitin A, Martchenko Shilman M.   +11 more
europepmc   +1 more source

A Keratinocyte‐Mast Cell NF‐κB2/CXCL2/IL‐6 Amplification Loop Enhances Cutaneous Antifungal Defense Against C. albicans

Advanced Science, EarlyView.
ABSTRACT Mast cells (MCs), key innate immune sentinels at the host–environment interface, serve as primary responders to invading pathogens. However, their specific contribution to host defense against cutaneous Candida albicans (C. albicans) infection and their synergy with other immune and non‐immune cells remain poorly understood. Here, we show that
Yan Yuan, Manyun Mao, Jiaan Zhang, Zhimin Duan, JiaNing Wang, Yujie Chen, Sihan Chen, Chuting Liang, Xvyue Zhou, Songmei Geng, Min Li, Xu Chen, Ni Lian   +12 more
wiley   +1 more source

Protective antigen having fluorinated histidine residues

, 2009
WSU inventors: James G. Bann, Dept. of Chemistry, Fairmount College of Liberal Arts and SciencesApplication No: 11/939,249 filed November 13, 2007. Patent No: US 20090123458 A1 granted May 14, 2009.The unnatural amino acid analogue 2-fluorohistidine (2 ...
Bann, James G.
core  

A Lyophilizable Nanoparticle Anthrax Vaccine Targeting the Loop-Neutralizing Determinant in Protective Antigen from <i>Bacillus anthracis</i>. [PDF]

Microorganisms
Oscherwitz J, Cease K, Milich D, Merkel T, Braun T, Yu F, Whitacre DC.   +6 more
europepmc   +1 more source

m6A‐Mediated Glycolysis by IL‐37 Drives T Cell Metabolic Reprogramming to Regulate Colitis

Advanced Science, EarlyView.
This study identifies an IL‐37/SIGIRR‐METTL14 regulatory axis that suppresses global m6A modification in CD4+ T cells. IL‐37 signaling, mediated through SIGIRR, inhibits IRAK4 and JNK phosphorylation, leading to downregulation of the methyltransferase METTL14.
Xiaoyan Wang, Jiadong Yu, Guolin Li, Ya Li, Fanlian Zeng, Jing Hu, Yifan Zhou, Chengcheng Yue, Qixiang Zhao, Chen Zhang, Hong Zhou, Fulei Zhao, Yawen Hu, Pei Zhou, Linna Gu, Yuting Feng, Mingxiang He, Shishi Huang, Xiaochi Sun, Xinmeng Wang, Jie Tang, Xinyu Zeng, Wenling Wu, Nongyu Huang, Xinai Cui, Kaijun Cui, Jiong Li   +26 more
wiley   +1 more source

Protective antigen having fluorinated histidine residues

, 2007
WSU inventor: James G. Bann, Dept. of Chemistry, College of Liberal Arts and SciencesAppl. no.: 11/939,249 filed Nov. 13, 2007. U.S. Patent 7,731,979 granted Jun 8, 2010.The unnatural amino acid analogue 2-fluorohistidine (2-FHis) was incorporated into ...
Bann, James G.
core  

A Self-Assembling Cross-Protective Antigen Against Multiple Gram-Positive Nosocomial Pathogens. [PDF]

ACS Omega
Kramarska E, Romero-Saavedra F, Squeglia F, Manna S, Sadones O, Marasco D, Berisio R, Huebner J.   +7 more
europepmc   +1 more source

Disruption of Treg Homeostasis in Rheumatoid Arthritis via Ferroptosis‐Mediated ETC Collapse and TXK‐STAT3/PLCγ1 Activation

Advanced Science, EarlyView.
In rheumatoid arthritis, synovial Tregs accumulate but are functionally impaired due to iron overload‐induced ferroptosis. This triggers mitochondrial dysfunction and TXK tyrosine kinase‐mediated signaling, leading to Treg destabilization and inflammation.
Jingrong Chen, Xiao Guan, Kexu Xiong, Xiaoyi Shi, Luyao Wu, Chuanxin Su, Jun Zhao, Rongzhen Liang, Huimin Wang, Junlong Dang, Ye Chen, Yiding Xiong, Chi Zhou, Futao Zhao, Zhenhang Zhu, Xiaoli Fan, Li Zhou, Nancy Olsen, Yutong Jiang, Song Guo Zheng   +19 more
wiley   +1 more source

Identification of a protective antigen reveals the trade-off between iron acquisition and antigen exposure in a global fungal pathogen. [PDF]

Proc Natl Acad Sci U S A
Li Y, Pham T, Hipsher K, Lee CWJ, Jiao J, Penninger JM, Kronstad JW, Fan Y, Zhao Y, Ambati S, Meagher RB, Xie X, Lin X.   +12 more
europepmc   +1 more source