Results 201 to 210 of about 697,104 (329)

Targeting the ARRDC3–DRP1 Axis via hUMSC‐Derived Exosomal CRYAB for Neuroprotection in Cerebral Ischemia/Reperfusion Injury

Advanced Healthcare Materials, EarlyView.
Intranasally administered hUMSC‐derived exosomes modulate the CRYAB–ARRDC3–Drp1 axis, alleviating mitochondrial dysfunction and ferroptosis, enhancing neuronal survival, reducing oxidative stress, and promoting functional recovery in ischemia‐reperfusion injury, offering a promising therapeutic strategy for ischemic stroke.
Rong ji, Zengyu Zhang, Zhuohang Liu, Kaicheng Yang, Xueyu Mao, Min Chu, Yong Wang, Jing Zhao   +7 more
wiley   +1 more source

MetE: a promising protective antigen for tuberculosis vaccine development. [PDF]

Front Immunol
Almujri SS, Stylianou E, Nicastri A, Satti I, Korompis M, Li S, De Voss CJ, Polo Peralta Alvarez M, Tanner R, Bettencourt PJG, Ternette N, McShane H.   +11 more
europepmc   +1 more source

Advances in Bioprinting to Model Immune‐Mediated Skin Diseases

Advanced Healthcare Materials, EarlyView.
This review explores how 3D bioprinting drives innovation in developing in vitro skin models that mimic immune‐mediated diseases. It highlights current technologies, key applications in studying skin pathologies, and emerging challenges. The review points toward future opportunities for improving disease modeling and advancing therapeutic and cosmetic ...
Andrea Ulloa‐Fernández, Marica Markovic, Julia Fernández‐Pérez, Georg Stary, Aleksandr Ovsianikov   +4 more
wiley   +1 more source

Serum IgG antibody response to the protective antigen (PA) of Bacillus anthracis induced by anthrax vaccine adsorbed (AVA) among U.S. military personnel

, 2008
Darrell E. Singer, Rachel Schneerson, Christian T. Bautista, Mark V. Rubertone, John B. Robbins, David N. Taylor   +5 more
openalex   +1 more source

Supplementary Figure Legend from Influenza Virus Infection Elicits Protective Antibodies and T Cells Specific for Host Cell Antigens Also Expressed as Tumor-Associated Antigens: A New View of Cancer Immunosurveillance

, 2023
Uzoma K. Iheagwara, Pamela Beatty, Phu T. Van, Ted M Ross, Jonathan S. Minden, Olivera J. Finn   +5 more
openalex   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

A Self-Assembling Cross-Protective Antigen Against Multiple Gram-Positive Nosocomial Pathogens. [PDF]

ACS Omega
Kramarska E, Romero-Saavedra F, Squeglia F, Manna S, Sadones O, Marasco D, Berisio R, Huebner J.   +7 more
europepmc   +1 more source

Evaluating the Antiviral Efficacy of Encapsulated PKC Inhibitor BIM‐I against influenza A Virus Infection

Advanced Healthcare Materials, EarlyView.
This study explores nanoparticle delivery of the protein kinase C inhibitor bisindolylmaleimide‐I (BIM‐I) to combat influenza A virus infections. Encapsulation in biodegradable PLGA nanoparticles improved safety while maintaining the compound's strong antiviral activity.
Laura Klement, Jana Ismail, Josefine Schroeder, Amod Godbole, Johanna Schreiber, Christine Weber, Zoltan Cseresnyes, Marc T. Figge, Bettina Löffler, Ulrich S. Schubert, Stephanie Schubert, Christina Ehrhardt, Carsten Hoffmann   +12 more
wiley   +1 more source

Screening of 71 P. multocida Proteins for Protective Efficacy in a Fowl Cholera Infection Model and Characterization of the Protective Antigen PlpE

, 2012
Tamás Hatfaludi, Keith Al‐Hasani, Lan Gong, John D. Boyce, Mark Ford, Ian Wilkie, Noelene S. Quinsey, Michelle A. Dunstone, David E. Hoke, Ben Adler   +9 more
openalex   +2 more sources

Identification of a protective antigen reveals the trade-off between iron acquisition and antigen exposure in a global fungal pathogen. [PDF]

Proc Natl Acad Sci U S A
Li Y, Pham T, Hipsher K, Lee CWJ, Jiao J, Penninger JM, Kronstad JW, Fan Y, Zhao Y, Ambati S, Meagher RB, Xie X, Lin X.   +12 more
europepmc   +1 more source