Results 71 to 80 of about 527,152 (301)
Anthrax Lethal Toxin and the Induction of CD4 T Cell Immunity
Toxins, 2012 Bacillus anthracis secretes exotoxins which act through several mechanisms including those that can subvert adaptive immunity with respect both to antigen presenting cell and T cell function.
Daniel M. Altmann +2 more
doaj +1 more source
A STUDY ON THE PROTECTIVE ANTIGEN OF PSEUDOMONAS AERUGINOSA
Nippon Jibiinkoka Gakkai Kaiho, 1966 It has been generally accepted that Pseudo- monas aeruginosa is one of the organisms most resistant to antibiotics. In the present study, Pseudomonas aeruginosa strain A3 was pursued in mice revealing its protective antigen localed in its cell wall. Preparation of cell walls during the present experiments was performed with mechanical des- truction and
openaire +3 more sources
Molecular Oncology, EarlyView.Single‐cell DNA methylation (scDNAme) profiling maps epimutational clonal evolution, revealing mechanisms of malignancy and therapeutic resistance across diverse cancer types. By providing a high‐resolution landscape of intratumoral heterogeneity, these technologies empower precise patient stratification, guide the development of enhanced ...
Ik Soo Kim
wiley +1 more source
, 2012 Advancements toward an improved vaccine against Bacillus anthracis, the causative agent of anthrax, have focused on formulations composed of the protective antigen (PA) adsorbed to aluminum hydroxide.
Y. Phanse +9 more
core +2 more sources
Antibodies against Anthrax: Mechanisms of Action and Clinical Applications
Toxins, 2011 B. anthracis is a bioweapon of primary importance and its pathogenicity depends on its lethal and edema toxins, which belong to the A-B model of bacterial toxins, and on its capsule.
Thibaut Pelat +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Interferon type 1 (IFN‐1) production and signaling is associated with the acquisition of therapy resistance, following chronic DNA damage, via Interferon‐related DNA damage resistance signature (IRDS) gene expression. An alternative, DNA damage‐independent role of sustained IFN‐1 mediated resistance was identified and characterized by the emergence of ...
Ashlyn Conant +11 more
wiley +1 more source
, 2023 IntroductionBacillus anthracis is the causative agent for the lethal disease anthrax, primarily affecting animals and humans in close contact with an infected host. The pathogenicity of B. anthracis is attributed to the secreted exotoxins and their outer
Shikhar Sharma (230953) +5 more
core +1 more source
Nano Aptasensor for Protective Antigen Toxin of Anthrax [PDF]
Analytical Chemistry, 2010 We demonstrate a highly sensitive nano aptasensor for anthrax toxin through the detection of its polypeptide entity, protective antigen (PA toxin) using a PA toxin ssDNA aptamer functionalized single-walled carbon nanotubes (SWNTs) device. The aptamer was developed in-house by capillary electrophoresis systematic evolution of ligands by exponential ...
Lakshmi N, Cella +5 more
openaire +2 more sources
FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
浙江大学学报. 农业与生命科学版, 2010 Adhesin is an important pathogenic factor of Aeromonas hydrophila which can cause disease in most fish in the area of Jiangsu and Zhejiang. The strains of TPS-30 and BSK-10 were assigned to serogroup O:9 and O:97 respectively, and the genes of the major ...
PAN Xiao-yi +4 more
doaj +1 more source