Foster care of children and adolescents who have had their rights violated is being discussed both in the scientific literature and in agencies involved in the development of public policies.
Nina Rosa do Amaral Costa +1 more
doaj
Effectiveness of Protective Measures and Rules in Reducing the Incidence of Injuries in Combat Sports: A Scoping Review. [PDF]
Štyriak R +4 more
europepmc +1 more source
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Healthcare Workers in Peril: Preparing to Protect Worker Health and Safety During Pandemic Influenza [PDF]
[Excerpt] An influenza pandemic is projected to have a global impact requiring a sustained, large scale response from the healthcare community to provide care to sick patients. Healthcare workers will be at very high risk of becoming infected when caring
AFL-CIO
core +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
U.S. trade policy towards developing countries [PDF]
The United States has often been criticized for protectionist measures taken against developing country products. Yet, average agricultural protection has reemained practically nil in the U.S. over time, while rising in the European Common Market (E.C.M)
Balassa, Bela
core
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
The impact of protective measures against COVID-19 on the wellbeing of residents in nursing homes and their relatives: a rapid review. [PDF]
Schneider P +4 more
europepmc +1 more source
Does Regulation of Built-In Security Reduce Crime? Evidence From a Natural Experiment [PDF]
As of 1999, all new-built homes in the Netherlands have to have burglary-proof windows and doors. We provide evidence that this large-scale government intervention in the use of self-protective measures lowers crime and improves social welfare.
Ours, J.C. van, Vollaard, B.A.
core +1 more source

