Results 41 to 50 of about 8,544,817 (263)

A script to highlight hydrophobicity and charge on protein surfaces [PDF]

, 2015
The composition of protein surfaces determines both affinity and specificity of protein-protein interactions. Matching of hydrophobic contacts and charged groups on both sites of the interface are crucial to ensure specificity.
Tania eMorán Luengo, Stefan G. D. Rüdiger, Dominique Hagemans, Cellular Protein Chemistry, Ianthe A. E. M. van Belzen, Ianthe A.E.M. van Belzen, van Belzen, Ianthe A E M, Sub Cellular Protein Chemistry, Morán Luengo, Tania, Rüdiger, Stefan G D, Tania Morán Luengo, Dominique eHagemans, Hagemans, Dominique   +12 more
core   +2 more sources

Hierarchical graph learning for protein–protein interaction

Nature Communications, 2023
Despite recent progress, machine learning methods remain inadequate in modeling the natural protein-protein interaction (PPI) hierarchy for PPI prediction.
Ziqi Gao, Chenran Jiang, Jiawen Zhang, Xiaosen Jiang, Lanqing Li, Peilin Zhao, Huanming Yang, Yong Huang, Jia Li   +8 more
doaj   +1 more source

Protein-protein interaction.

, 2022
STRING software depicts the protein-protein interaction network of XRCC2, XRCC3 and RAD51. The first ten proteins that primarily interacts with XRCC2, XRCC3 and RAD51 is highlighted.
Nageswara Rao Dunna (11985969), Taruna Rajagopal (11985957), Srikanth Talluri (442338), Krishna Kumar Rathnam (11985963), Sivaramakrishnan Venkatabalasubramanian (11985966), Arun Seshachalam (11985960)   +5 more
core   +1 more source

Allo-network drugs: Extension of the allosteric drug concept to protein-protein interaction and signaling networks [PDF]

, 2013
Allosteric drugs are usually more specific and have fewer side effects than orthosteric drugs targeting the same protein. Here, we overview the current knowledge on allosteric signal transmission from the network point of view, and show that most ...
Csermely, Péter, Nussinov, Ruth, Szilágyi, András, Nussinov R   +3 more
core   +2 more sources

Additional file 14: Table S1. of A yeast two-hybrid system for the screening and characterization of small-molecule inhibitors of proteinâ protein interactions identifies a novel putative Mdm2-binding site in p53

, 2017
List of plasmids used in the study. (PDF 66 kb)
Wong, Jin, Alfatah, Mohammad, Sin, Mei, Sim, Hong, Verma, Chandra, Lane, David, Arumugam, Prakash   +6 more
openaire   +1 more source

Analysis of leukocyte membrane protein interactions using protein microarrays [PDF]

, 2005
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work
Foster-Cuevas, M, Letarte, Michelle, Deborah Hatherley, Foster-Cuevas, Mildred, Hatherley, D, Barclay, AN, Michelle Letarte, Saunders, Nigel, A Neil Barclay, Saunders, NJ, Hatherley, Deborah, Letarte, M, Barclay, Neil, Mildred Foster-Cuevas, Nigel J Saunders, Saunders, Nigel J, Voulgaraki, D, Despina Voulgaraki, Voulgaraki, Despina   +18 more
core   +1 more source

A web-based protein interaction network visualizer [PDF]

, 2014
Background Interaction between proteins is one of the most important mechanisms in the execution of cellular functions. The study of these interactions has provided insight into the functioning of an organism’s processes.
Holifidy A Rapanoël, Mazandu, Gaston K, Ayton Meintjes, Gustavo A Salazar, Salazar, Gustavo A, Gaston K Mazandu, Rapanoël, Holifidy A, Akinola, Richard O, Meintjes, Ayton, Richard O Akinola, Mulder, Nicola J, Nicola J Mulder   +11 more
core   +1 more source

Discovering functional interaction patterns in protein-protein interaction networks

BMC Bioinformatics, 2008
Background In recent years, a considerable amount of research effort has been directed to the analysis of biological networks with the availability of genome-scale networks of genes and/or proteins of an increasing number of organisms.
Can Tolga, Turanalp Mehmet E
doaj   +1 more source

Protein-protein interaction hotspots carved into sequences. [PDF]

PLoS Computational Biology, 2007
Protein-protein interactions, a key to almost any biological process, are mediated by molecular mechanisms that are not entirely clear. The study of these mechanisms often focuses on all residues at protein-protein interfaces.
Yanay Ofran, Burkhard Rost
doaj   +1 more source

ProDGe: investigating protein-protein interactions at the domain level [PDF]

, 2011
An important goal of systems biology is the identification and investigation of known and predicted protein-protein interactions to obtain more information about new cellular pathways and processes.
Andreas Dräger, Clemens Wrzodek, Adrian Schröder, Adrian Schröder, Florian Mittag, Andreas Zell, Finja Büchel, Andreas Dräger, Finja Büchel   +8 more
core   +1 more source