Results 21 to 30 of about 8,544,817 (263)

Protein complex prediction in large protein–protein interaction network

open access: yesInformatics in Medicine Unlocked, 2022
Due to high computational complexity, the detection of protein complexes in large protein–protein interaction (PPI) networks remains a challenging problem.
Md. Shahidul Islam   +2 more
doaj   +1 more source

Prediction of protein-protein interaction types using association rule based classification [PDF]

open access: yes, 2009
This article has been made available through the Brunel Open Access Publishing Fund - Copyright @ 2009 Park et alBackground: Protein-protein interactions (PPI) can be classified according to their characteristics into, for example obligate or transient ...
José A Reyes   +14 more
core   +1 more source

Fitting a geometric graph to a protein-protein interaction network [PDF]

open access: yes, 2008
Finding a good network null model for protein-protein interaction (PPI) networks is a fundamental issue. Such a model would provide insights into the interplay between network structure and biological function as well as into evolution.
Higham, Desmond J.   +2 more
core   +4 more sources

CHAPTER 1.1. Disulfide Bonds in Protein Folding and Stability [PDF]

open access: yes, 2018
Disulfide bonds are unique among post-translational modifications, as they add covalent crosslinks to the polypeptide chain. Accordingly, they can exert pronounced effects on protein folding and stability. This is of particular importance for secreted or
Sub Cellular Protein Chemistry   +7 more
core   +1 more source

Hsp90 Breaks the Deadlock of the Hsp70 Chaperone System [PDF]

open access: yes, 2018
Protein folding in the cell requires ATP-driven chaperone machines such as the conserved Hsp70 and Hsp90. It is enigmatic how these machines fold proteins.
Mayer, Matthias   +5 more
core   +2 more sources

Construction and analysis of the protein-protein interaction network of visual system in Drosophila [PDF]

open access: yesNetwork Biology, 2023
Insects are one of the most widely distributed animals on earth, and their visual systems have strong adaptability, deeply affecting their survival, reproduction, diet, and environmental adaptation.
JiaNing Sun, WenJun Zhang
doaj  

Sequence Motifs in MADS Transcription Factors Responsible for Specificity and Diversification of Protein-Protein Interaction [PDF]

open access: yes, 2010
Protein sequences encompass tertiary structures and contain information about specific molecular interactions, which in turn determine biological functions of proteins.
Angenent, G.C.   +23 more
core   +2 more sources

Expressed protein ligation for a large dimeric protein [PDF]

open access: yes, 2011
Expressed protein ligation (EPL) is a protein engineering tool for post-translational ligation of protein or peptide fragments. This technique allows modification of specific parts of proteins, opening possibilities for incorporating probes for ...
NMR Spectroscopy   +11 more
core   +1 more source

Pyramidalization of the Glycosidic Nitrogen Provides the Way for Efficient Cleavage of the N‑Glycosidic Bond of 8‑OxoG with the hOGG1 DNA Repair Protein [PDF]

open access: yes, 2012
A mechanistic pathway for cleavage of the N-glycosidic bond of 8-oxo-2′-deoxyguanosine (oxoG) catalyzed with the human 8-oxoguanine glycosylase 1 DNA repair protein (hOGG1) is proposed in this theoretical study. The reaction scheme suggests direct proton
Sychrovský, V.   +5 more
core   +1 more source

Predicting protein phenotypes based on protein-protein interaction network. [PDF]

open access: yesPLoS ONE, 2011
BackgroundIdentifying associated phenotypes of proteins is a challenge of the modern genetics since the multifactorial trait often results from contributions of many proteins.
Lele Hu   +3 more
doaj   +1 more source

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