DCSE:Double-Channel-Siamese-Ensemble model for protein protein interaction prediction
BMC Genomics, 2022 Background Protein-protein interaction (PPI) is very important for many biochemical processes. Therefore, accurate prediction of PPI can help us better understand the role of proteins in biochemical processes.
Wenqi Chen +5 more
doaj +1 more source
Controllability of protein-protein interaction phosphorylation-based networks: Participation of the hub 14-3-3 protein family [PDF]
, 2016 Posttranslational regulation of protein function is an ubiquitous mechanism in eukaryotic cells. Here, we analyzed biological properties of nodes and edges of a human protein-protein interaction phosphorylation-based network, especially of those nodes ...
Bustos, Diego Martin +2 more
core +1 more source
SLIDER: Mining correlated motifs in protein-protein interaction networks [PDF]
, 2009 —Correlated motif mining (CMM) is the problem to find overrepresented pairs of patterns, called motif pairs, in interacting protein sequences. Algorithmic solutions for CMM thereby provide a computational method for predicting binding sites for protein ...
Boyen, P. +3 more
core +2 more sources
Global protein function prediction in protein-protein interaction networks
, 2003 The determination of protein functions is one of the most challenging problems of the post-genomic era. The sequencing of entire genomes and the possibility to access gene's co-expression patterns has moved the attention from the study of single proteins
Flammini, A. +3 more
core +2 more sources
Small-molecule CaVα1⋅CaVβ antagonist suppresses neuronal voltage-gated calcium-channel trafficking [PDF]
, 2018 Extracellular calcium flow through neuronal voltage-gated CaV2.2 calcium channels converts action potential-encoded information to the release of pronociceptive neurotransmitters in the dorsal horn of the spinal cord, culminating in excitation of the ...
Chen, Xingjuan +10 more
core +1 more source
The Relationship between the UniProt Knowledgebase (UniProtKB) and the IntAct Molecular Interaction Databases [PDF]
, 2009 IntAct provides a freely available, open source database system and analysis tools for protein interaction data. All interactions are derived from literature curation or direct user submission and all experimental information relating to binary protein ...
Yasmin Alam-Faruque
core +3 more sources
Sensitivity dependent model of protein-protein interaction networks
, 2008 The scale free structure p(k)~k^{-gamma} of protein-protein interaction networks can be reproduced by a static physical model in simulation. We inspect the model theoretically, and find the key reason for the model to generate apparent scale free degree ...
Estojak J +3 more
core +1 more source
Heterologous prion-forming proteins interact to cross-seed aggregation in Saccharomyces cerevisiae [PDF]
, 2017 The early stages of protein misfolding remain incompletely understood, as most mammalian proteinopathies are only detected after irreversible protein aggregates have formed.
Keefer, Kathryn M +2 more
core +2 more sources
, 2017 List of yeast strains used in the study. (PDF 111 kb)
Wong, Jin +6 more
openaire +1 more source
Clustering Coefficients of Protein-Protein Interaction Networks
, 2007 The properties of certain networks are determined by hidden variables that are not explicitly measured. The conditional probability (propagator) that a vertex with a given value of the hidden variable is connected to k of other vertices determines all ...
B. Alberts +4 more
core +1 more source