Protein complex prediction in large protein–protein interaction network
Informatics in Medicine Unlocked, 2022 Due to high computational complexity, the detection of protein complexes in large protein–protein interaction (PPI) networks remains a challenging problem.
Md. Shahidul Islam +2 more
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Construction and analysis of the protein-protein interaction network of visual system in Drosophila [PDF]
Network Biology, 2023 Insects are one of the most widely distributed animals on earth, and their visual systems have strong adaptability, deeply affecting their survival, reproduction, diet, and environmental adaptation.
JiaNing Sun, WenJun Zhang
doaj
MAPPI-DAT : data management and analysis for protein-protein interaction data from the high-throughput MAPPIT cell microarray platform [PDF]
, 2017 Protein-protein interaction (PPI) studies have dramatically expanded our knowledge about cellular behaviour and development in different conditions. A multitude of high-throughput PPI techniques have been developed to achieve proteome-scale coverage for ...
De Puysseleyr, Veronic +8 more
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STRING and STITCH: known and predicted interactions between proteins and chemicals [PDF]
, 2008 Information on protein-protein and protein-chemical interactions is essential for understanding cellular functions. The STRING and STITCH web resources integrate interaction evidence derived from pathways, automatic literature mining, primary ...
Christian von Mering +5 more
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Predicting protein phenotypes based on protein-protein interaction network. [PDF]
PLoS ONE, 2011 BackgroundIdentifying associated phenotypes of proteins is a challenge of the modern genetics since the multifactorial trait often results from contributions of many proteins.
Lele Hu +3 more
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Relation Extraction of Protein Complexes from Dynamic Protein-Protein Interaction Network [PDF]
Journal of Biomedical Physics and Engineering, 2021 Background: Dynamic protein-protein interaction networks (DPPIN) can confirm the conditional and temporal features of proteins and protein complexes. In addition, the relation of protein complexes in dynamic networks can provide useful information in ...
Moslem Mohammadi Jenghara +2 more
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Molecular Systems Biology, 2015 Mitogen‐activated protein kinases (MAPK) are broadly used regulators of cellular signaling. However, how these enzymes can be involved in such a broad spectrum of physiological functions is not understood.
András Zeke +8 more
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ProDGe: investigating protein-protein interactions at the domain level [PDF]
, 2011 An important goal of systems biology is the identification and investigation of known and predicted protein-protein interactions to obtain more information about new cellular pathways and processes.
Adrian Schrö +5 more
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Memory in repetitive protein–protein interaction series
APL Bioengineering, 2023 Interactions between proteins coordinate biological processes in an organism and may impact its responses to changing environments and diseases through feedback systems. Feedback systems function by using changes in the past to influence behaviors in the
Aaron M. Rosado +8 more
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Hierarchical graph learning for protein–protein interaction
Nature Communications, 2023 Despite recent progress, machine learning methods remain inadequate in modeling the natural protein-protein interaction (PPI) hierarchy for PPI prediction.
Ziqi Gao +8 more
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