Results 251 to 260 of about 1,962,138 (310)

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Comparative analysis of the extent of protein-protein interactions in icosahedral viral capsids. [PDF]

Protein Sci
Zimmerman NJ, Labra OR, Reddy VS.
europepmc   +1 more source

SARS-CoV-2 nonstructural protein 3 remodels the phosphorylation of target proteins via protein-protein interactions. [PDF]

Microbiol Spectr
Yang H, Peng D, Martinez-Sobrido L, Ye C.   +3 more
europepmc   +1 more source

MutPPI+: a multimodal framework for predicting mutation effects on protein-protein interactions via mutation-path-based data augmentation. [PDF]

Brief Bioinform
Deng J, Gu M, Zhang P, Liu T, Hu G, Dong M, Zhang Y, Song Y, Zhang Y, Liu M, Tian J, Cheng W.   +11 more
europepmc   +1 more source

EXPRESSION OF CONCERN: DIMP53‐1: A Novel Small‐Molecule Dual Inhibitor of p53–MDM2/X Interactions with Multifunctional p53‐Dependent Anticancer Properties

Molecular Oncology, EarlyView.
wiley   +1 more source

Enhancement of Protein-Protein Interactions by Destabilizing Mutations Revealed by HDX-MS. [PDF]

Biomolecules
Hamuro Y, Armstrong A, Branson J, Wu SJ, Huang RY, Jacobs S.   +5 more
europepmc   +1 more source

Enhancing mutation impact prediction in protein-protein interactions through interpretable graph-based multi-level feature interactions. [PDF]

Bioinformatics
Wu S, Xu N, Xin X, Zhang M, Liu H, Zhu H, Wei Z, Zhao C, Yu L, Feng W.   +9 more
europepmc   +1 more source

Challenges in predicting protein-protein interactions of understudied viruses: Arenavirus-human interactions. [PDF]

Comput Struct Biotechnol J
Sahni H, Crotzer SM, Moore J, Branda SS, Estrada T, Gnanakaran S.   +5 more
europepmc   +1 more source

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Protein–protein interactions

Biochemical Society Transactions, 2010
In the present article, we describe the two standard high-throughput methods for identification of protein complexes: two-hybrid screens and TAP (tandem affinity purification) tagging. These methods have been used to characterize the interactome of Saccharomyces cerevisiae, showing that the majority of proteins are part of complexes, and that complexes
Williamson, Mike P., Sutcliffe, Michael J.   +1 more
openaire   +3 more sources

DISCOVERING PROTEIN–PROTEIN INTERACTIONS

Journal of Bioinformatics and Computational Biology, 2004
The ongoing genomics and proteomics efforts have helped identify many new genes and proteins in living organisms. However, simply knowing the existence of genes and proteins does not tell us much about the biological processes in which they participate. Many major biological processes are controlled by protein interaction networks.
See-Kiong Ng, Soon-Heng Tan
openaire   +2 more sources