Mice lacking protein tyrosine kinase fyn develop a T helper-type 1 response and resistLeishmania major infection [PDF]
Kazuo Yamakami +4 more
openalex +1 more source
This review explores advances in wearable and lab‐on‐chip technologies for breast cancer detection. Covering tactile, thermal, ultrasound, microwave, electrical impedance tomography, electrochemical, microelectromechanical, and optical systems, it highlights innovations in flexible electronics, nanomaterials, and machine learning.
Neshika Wijewardhane +4 more
wiley +1 more source
A Method for Overcoming Plasma Protein Inhibition of Tyrosine Kinase Inhibitors [PDF]
David J. Young +6 more
openalex +1 more source
Smart REASSURED Sensors via Machine‐Augmented Printable On‐Paper Arrays
This perspective highlights the emerging role of pattern‐recognition, printable on‐paper sensor arrays for intelligent PoC diagnostics. It discusses how paper's inherent limitations can be overcome through surface modification and scalable printing, and how machine‐learning analysis of cross‐reactive arrays enables multiplexed, low‐cost, and REASSURED ...
Naimeh Naseri, Saba Ranjbar
wiley +1 more source
Mitotic Activation of Protein-tyrosine Phosphatase α and Regulation of Its Src-mediated Transforming Activity by Its Sites of Protein Kinase C Phosphorylation [PDF]
Xinmin Zheng +2 more
openalex +1 more source
Circular RNA PTPN4 Contributes to Blood‐Brain Barrier Disruption during Early Epileptogenesis
Epileptic condition induces CircPTPN4 upregulation, which promotes ECE‐1 expression through competitive sequestration of miR‐145a‐5p. The elevated ECE‐1 catalyzes the ET‐1 production, leading to p38/MAPK pathway activation and subsequent downregulation of tight junction protein expression. This cascade results in increased BBB permeability and enhanced
Jiurong Yang +16 more
wiley +1 more source
T Cell Development and T Cell Responses in Mice with Mutations Affecting Tyrosines 292 or 315 of the Zap-70 Protein Tyrosine Kinase [PDF]
A. Magnan +11 more
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In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong +11 more
wiley +1 more source
Spatial regulation of signaling by the coordinated action of the protein tyrosine kinases MET and FER. [PDF]
Zhang J +7 more
europepmc +1 more source

